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Mentorship in patient-oriented research on behavioral and social determinants of cardiometabolic health

指导以患者为中心的心脏代谢健康行为和社会决定因素的研究

基本信息

批准号：
10589326
负责人：
Anne N Thorndike
金额：
$ 12.65万
依托单位：
MASSACHUSETTS GENERAL HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-02-01 至 2028-01-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10589326
关键词：
Address Adherence Adult Appointment Architecture Award Behavior Behavior Therapy Behavioral Beverages Blood Pressure Body mass index Cardiometabolic Disease Chronic Chronic Disease Collaborations Communities Community Developments Community Health Aides Consumption Data Dedications Development Diet Diet Modification Dietary Intervention Dietary intake Disease Education Effectiveness Effectiveness of Interventions Faculty Food Food Labeling Frontline worker Funding Future General Hospitals General Practices Goals Health Health Food Health behavior Healthcare High Prevalence Home Hypertension Individual Infrastructure Internist Intervention Interview Knowledge Label Life Style Light Longitudinal cohort Low Income Population Low income Massachusetts Medical Medicine Mental Depression Mentored Patient-Oriented Research Career Development Award Mentors Mentorship Methods Mid-Career Clinical Scientist Award (K24)Monitor Neighborhood Health Center Nutritional Outcome Paper Participant Patients Personal Satisfaction Pharmaceutical Preparations Pilot Projects Policies Populations at Risk Postdoctoral Fellow Prevention Primary Care Process Public Health Publications Randomized Research Research Personnel Research Support Resources Security Sleep Socioeconomic Factors Students Supermarket Surveys Testing Time Training Unhealthy Diet United States National Institutes of Health Visit Workplace Writing acceptability and feasibility adverse outcome blood pressure control cardiometabolic risk cardiometabolism cardiovascular health cardiovascular risk factor career career development cohort community setting design dietary disease disparity dissemination research experience food insecurity food resource food security health care availability health care service utilization high risk hypertension control implementation intervention implementation research improved improved outcome interest marginalized population medical schools medication compliance mid-career faculty novel novel strategies nutrition nutrition education participant enrollment patient engagement patient oriented patient oriented research pilot test prevent primary care patient primary outcome programs psychologic secondary outcome social social determinants social factors social health determinants socioeconomic disparity socioeconomics

项目摘要

Anne Thorndike, MD, MPH is a practicing general internist at Massachusetts General Hospital (MGH) and an Associate Professor of Medicine at Harvard Medical School. The purpose of this K24 mid-career investigator award is to support Dr. Thorndike’s mentorship and patient-oriented research focused on health behaviors and social determinants of health in the prevention and treatment of cardiometabolic disease. Over the past 10 years, her research in workplace and community settings has tested novel behavioral strategies to promote healthy dietary intake and other healthy behaviors to prevent chronic disease, particularly in low-income populations with high prevalence of food insecurity and other unmet health-related social needs. Many of these strategies, such as traffic-light food labeling and choice architecture (product placement), have been broadly disseminated through academic, governmental, and lay publications. Dr. Thorndike is a dedicated mentor, and she has supported over 25 junior faculty, medical residents, postdoctoral fellows, and students. Her mentees have written 19 first author papers (5 in process) and have received 5 NIH K23 awards (1 in review). In this K24 application, Dr. Thorndike proposes a mentoring, career development, and research plan with inter-related goals that will help advance the research of Dr. Thorndike and her mentees to address some of the most intractable behavioral and social factors that contribute to cardiometabolic disease disparities. The overall objectives of the K24 award are: 1) To enable Dr. Thorndike to dedicate 25% protected time for mentoring early-career investigators conducting patient-oriented research focused on health behaviors and social determinants of cardiometabolic health, 2) To have a platform for mid-career professional development and training, in collaboration with expert collaborators and co-mentors, and 3) To integrate her existing NIH-funded research with new research supported by this award that will support a future R01 submission. The proposed research uses mixed methods to develop a community health worker (CHW) nutrition intervention for community health center patients experiencing uncontrolled hypertension and food insecurity. Research Aim 1 will leverage the existing longitudinal “LiveWell” cohort of over 1,000 community health center patients (R01 DK124145, Thorndike) to conduct formative research that will inform the development of the CHW nutrition intervention. Using the infrastructure of an existing MGH CHW hypertension program, Research Aim 2 will be a randomized 6-month pilot study to determine feasibility and acceptability of delivering a nutrition intervention with CHWs and to determine preliminary effectiveness of the intervention on patients’ dietary intake, blood pressure, body mass index, and depression. Dr. Thorndike’s ongoing NIH-funded research and proposed new research provide opportunities for mentorship in patient-oriented research focused on the development and implementation of interventions that will improve outcomes and reduce socioeconomic disparities in cardiometabolic health.

Anne Thorndike，医学博士，公共卫生硕士，是马萨诸塞州总医院（MGH）的执业全科内科医生，哈佛医学院医学副教授。这位K24职业生涯中期调查员的目的该奖项是为了支持桑代克博士的指导和以病人为导向的研究，重点是健康行为，健康的社会决定因素在预防和治疗心脏代谢疾病中的作用。过去10 多年来，她在工作场所和社区环境的研究已经测试了新的行为策略，以促进健康的饮食摄入和其他健康的行为，以预防慢性病，特别是在低收入粮食不安全和其他与健康有关的社会需求得不到满足的人口比例很高。许多这些战略，如交通灯食品标签和选择架构（产品植入），已被广泛通过学术、政府和非专业出版物传播。桑代克博士是一位敬业的导师，她支持了超过25名初级教师，住院医师，博士后研究员和学生。她的学员撰写了19篇第一作者论文（5篇正在撰写中），并获得了5项NIH K23奖（1项正在评审中）。在这 K24应用程序，桑代克博士提出了一个指导，职业发展和研究计划与相互关联目标，这将有助于推进桑代克博士和她的学员的研究，以解决一些最顽固的行为和社会因素导致心脏代谢疾病的差异。整体 K24奖的目标是：1）使桑代克博士能够将25%的受保护时间用于指导早期职业调查人员进行以病人为导向的研究，重点是健康行为和社会心脏代谢健康的决定因素，2）为职业生涯中期的专业发展提供平台，培训，与专家合作者和共同导师合作，3）整合她现有的NIH资助的该奖项支持的新研究将支持未来的R 01提交。拟议研究使用混合方法开发社区卫生工作者（CHW）营养干预，社区卫生中心的患者患有不受控制的高血压和食物不安全。研究目标1 将利用现有的1,000多名社区卫生中心患者的纵向“LiveWell”队列（R 01 DK 124145，Thorndike）进行形成性研究，为CHW营养的开发提供信息干预使用现有的MGH CHW高血压项目的基础设施，研究目标2将是一个一项为期6个月的随机试点研究，以确定提供营养干预的可行性和可接受性并确定干预对患者的饮食摄入量，血液压力、体重指数和抑郁症。桑代克博士正在进行的NIH资助的研究，并提出了新的研究提供机会，指导以病人为导向的研究，重点是发展和实施干预措施，改善成果，减少社会经济差距，心脏代谢健康