Timing Of Exercise In Concussed Rat Athletes
Timing Of Exercise In Concussed Rat Athletes
批准号:
10576291
负责人:
Mayumi Lynn Prins
金额:
$48.32万
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
未结题
起止时间:
2019-03-01 至 2025-02-28
关键词:
AddressAdolescentAdolescent and Young AdultAdultAffectAgeAnimalsAnxietyBehavioralBiogenesisBiological MarkersBrainBrain ConcussionBrain InjuriesBrain-Derived Neurotrophic FactorCerebrumClassificationDevelopmentEquilibriumExerciseExperimental ModelsExposure toFemaleFunctional disorderGlucoseGlutamatesGoalsGrantGuidelinesHomeImpaired cognitionInjuryMale AdolescentsMental DepressionMetabolicMitochondriaModelingMonitorN-acetylaspartatePhysical activityPhysiologyPlayPopulationProtocols documentationPsyche structureRattusRecoveryReportingResearchRestRiskRodentRoleRunningSeveritiesSex DifferencesSocial InteractionSocializationSportsStandardizationStudy modelsSymptomsSynaptophysinTimeTrainingTraumatic Brain InjuryWorkadolescent healthallodyniabrain healthclinical translationclinically relevantcognitive testingexperimental studyglucose metabolismimproved outcomeinsightmalemetabolic depressionmetabolic ratemild traumatic brain injuryneurochemistrypain sensitivitypreventreduce symptomsresponseresponse to brain injurysedentarysex
中文摘要
项目总结/摘要
反复脑震荡是青少年和年轻成年运动员日益关注的问题。实验
其中一个问题是,没有人以“运动员”模式来解决这个问题。越来越多的证据
研究表明,那些经常锻炼的人(运动员)的大脑与那些经常锻炼的人(运动员)的大脑非常不同。
久坐的。这些差异将影响“运动员大脑”对脑震荡损伤的反应。在这
应用我们已经开发了一个rathlete模型来研究脑震荡损伤和恢复的影响
运动员大脑和非运动员大脑之间的差异。这项工作不仅将
提供有关脑损伤研究的重要信息,但强调运动在
青少年健康
英文摘要
Project Summary/Abstract
Repeat concussions are a growing concern for adolescents and young adult athletes. Experimentally
one of the problems is that no one has been addressing this in an “athlete” model. Growing evidence
shows that the brains of those that exercise regularly (athletes) are very different than those that are
sedentary. These differences will affect how the “athlete brain” responds to concussive injuries. In this
application we have developed a rathlete model to study the effects of concussive injuries and recovery
between the athlete brain and non-athlete brain in both male and female rats. This work will not only
provide important information regarding brain injury research, but emphasize the role of exercise in
adolescent health.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Cerebral Substrate Support After Traumatic Brain Injury
-
批准号:10447053
-
项目类别:
-
资助金额:$34.13万
-
财政年份:2018
-
负责人:Mayumi Lynn Prins
-
依托单位:
Cerebral Substrate Support After Traumatic Brain Injury
-
批准号:10199063
-
项目类别:
-
资助金额:$34.13万
-
财政年份:2018
-
负责人:Mayumi Lynn Prins
-
依托单位:
Cerebral Substrate Support After Traumatic Brain Injury
-
批准号:9788536
-
项目类别:
-
资助金额:$34.13万
-
财政年份:2018
-
负责人:Mayumi Lynn Prins
-
依托单位:
Age-Dependent Ketone Metabolism After Brain Injury
-
批准号:7076205
-
项目类别:
-
资助金额:$24.42万
-
财政年份:2005
-
负责人:Mayumi Lynn Prins
-
依托单位:
Age-Dependent Ketone Metabolism After Brain Injury
-
批准号:7254100
-
项目类别:
-
资助金额:$23.71万
-
财政年份:2005
-
负责人:Mayumi Lynn Prins
-
依托单位:
Age-Dependent Ketone Metabolism After Brain Injury
-
批准号:6958787
-
项目类别:
-
资助金额:$25.01万
-
财政年份:2005
-
负责人:Mayumi Lynn Prins
-
依托单位:
Age-dependent use of alternative cerebral substrates during metabolic depression
-
批准号:8460076
-
项目类别:
-
资助金额:$19.52万
-
财政年份:--
-
负责人:Mayumi Lynn Prins
-
依托单位:
Age-dependent use of alternative cerebral substrates during metabolic depression
-
批准号:8043503
-
项目类别:
-
资助金额:$20.39万
-
财政年份:--
-
负责人:Mayumi Lynn Prins
-
依托单位:
Age-dependent use of alternative cerebral substrates during metabolic depression
-
批准号:7663688
-
项目类别:
-
资助金额:$20.6万
-
财政年份:--
-
负责人:Mayumi Lynn Prins
-
依托单位:
Age-dependent use of alternative cerebral substrates during metabolic depression
-
批准号:8376070
-
项目类别:
-
资助金额:$20.39万
-
财政年份:--
-
负责人:Mayumi Lynn Prins
-
依托单位:
Age-dependent use of alternative cerebral substrates during metabolic depression
-
批准号:8246429
-
项目类别:
-
资助金额:$21.38万
-
财政年份:--
-
负责人:Mayumi Lynn Prins
-
依托单位:
海外基金