Skeletal Muscle: Development, Regeneration and Disease
Skeletal Muscle: Development, Regeneration and Disease
批准号:
10237575
负责人:
Elizabeth H Chen
金额:
$2.0万
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-05-06 至 2022-04-30
关键词:
AddressAffectApplications GrantsAreaAttentionBasic ScienceBiologyBiomedical EngineeringCell TherapyCellsClinicalCollaborationsCommunitiesCountryDevelopmentDiseaseDisease modelDuchenne muscular dystrophyEmerging TechnologiesEnsureEpigenetic ProcessExtracellular MatrixFacioscapulohumeralFacultyFertilizationFosteringGenerationsGeneticGenetic TranscriptionGeographyGoalsGrowthHumanInternationalItalyLeadMalignant NeoplasmsMentorsMinorityModelingMolecular and Cellular BiologyMuscleMuscle DevelopmentMuscle satellite cellMuscular DystrophiesMyoblastsMyopathyNatural regenerationPoliciesPostdoctoral FellowRegulationResearchResearch PersonnelRhabdomyosarcomaScienceScientistSeriesSkeletal MuscleSlideSocietiesStudentsTherapeuticTissue ModelTissuesTranslatingTranslational ResearchWomanWorkcareer developmentcareer networkingdiversity and inclusiondoctoral studentepigenetic regulationexperiencefrontiergene therapygraduate studenthuman diseaseinduced pluripotent stem cellmalignant muscle neoplasmmeetingsmetabolic abnormality assessmentmolecular dynamicsmuscle metabolismmuscle regenerationmyogenesisnovelnovel strategiesnovel therapeuticspostersprofessorprogramsrepairedsymposiumtherapy developmenttissue repairunpublished works
中文摘要
总结
“骨骼肌:发展,再生和疾病”会议的目标是汇集
骨骼肌研究的国际领导者,为尖端的遗传,细胞和
肌肉发育、再生和疾病的分子生物学基础。肌生成前沿
由肌肉生物学学会组织的系列活动在过去的二十年里每三年举行一次,
已经成功地定义了该领域的最新技术。2021年的会议不仅将讨论最近的发现,
在骨骼肌发育和修复方面,也将包括我们对人类发育和修复的理解的进展。
疾病,包括肌肉萎缩症和癌症。我们的主讲人将是埃里克·奥尔森博士,
在肌肉发育方面进行了出色的工作,并制定了治疗杜氏症的治疗策略
肌肉萎缩症计划举行11次全体会议,讨论以下主题:细胞和分子
骨骼肌发育的动力学,成肌细胞融合和肌肉生长,肌肉干细胞调节,
骨骼肌的表观遗传调控,iPS细胞,生物工程和新兴技术的研究和修复
骨骼肌,肌肉代谢和癌症,肌肉组织和疾病模型,
骨骼肌修复和疾病,肌肉疾病机制,并将骨骼肌科学转化为
新疗法特邀演讲者(36名)因其在科学方面的卓越表现而被选中,
适当的代表性(42%的女性/少数民族)和地理多样性(39%来自非美国
国家)。此外,将从提交的摘要中选出19个简短的演讲,
博士后和学生展示他们的工作。演讲者被明确要求谈论未发表的作品,
确保科学讨论集中在该领域的最前沿。此外,我们还将举办三场海报会议,
每一个都伴随着一个“海报闪电战”,海报主持人将给一个1分钟的演讲,突出/宣传
他们的工作。为了进一步促进互动,我们将组织午餐会,以便发言者均匀分布
与会者可以注册加入他们的餐桌。最后,我们还包括两个专业发展会议
讨论拨款申请,以及科学的多样性和包容性。本次会议将提供一个论坛,
讨论骨骼肌研究的最新发现,并促进研究人员之间的交流
从不同的领域和背景,以进一步推进我们对肌肉生物学的理解,并促进
开发肌肉疾病潜在疗法的转化努力。
英文摘要
SUMMARY
The goal of the “Skeletal muscle: development, regeneration and disease” conference is to bring together
international leaders in skeletal muscle research to provide a forum for cutting edge genetic, cellular and
molecular biology underlying muscle development, regeneration and disease. This Frontiers in Myogenesis
series organized by the Society for Muscle Biology has been held every three years for the last twenty years and
has successfully defined the state of the art in the field. The 2021 meeting will not only discuss recent discoveries
in skeletal muscle development and repair, but will also encompass advances in our understanding of human
diseases, including muscular dystrophies and cancer. Our keynote speaker will be Dr. Eric Olson, who has
performed exceptional work in muscle development and developed therapeutic strategies for treating Duchenne
muscular dystrophy. Eleven plenary sessions are planned to address the following topics: cellular and molecular
dynamics of skeletal muscle development, myoblast fusion and muscle growth, muscle stem cell regulation,
epigenetic regulation of skeletal muscle, iPS cells, bioengineering and emerging technologies to study and repair
skeletal muscle, muscle metabolism and cancer, muscle tissue and disease models, microenvironment in
skeletal muscle repair and disease, muscle disease mechanisms, and translating skeletal muscle science into
new therapies. Invited speakers (36) have been selected for their scientific excellence, with particular attention
to appropriate representation (42% women/minorities) and geographical diversity (39% are from non-US
countries). In addition, 19 short talks will be selected from submitted abstracts to provide opportunities for
postdocs and students to present their work. Speakers are explicitly required to talk about unpublished work, to
ensure scientific discussions focused at the forefront of the field. In addition, we will have three poster sessions
each accompanied by a “posters blitz” where poster presenters will give a 1-minute talk to highlight/advertise
their work. To further foster interaction, we will organize lunch sessions so that speakers are evenly distributed
and attendees can sign up to join their table. Finally, we have included two professional development sessions
to discuss grant application, as well as diversity and inclusion in science. This Conference will provide a forum
for discussing recent discoveries in skeletal muscle research, and foster cross-fertilization among investigators
from diverse areas and backgrounds, to further advance our understanding of muscle biology and facilitate the
development of translational efforts for potential therapies for muscle diseases.
期刊论文(0)
专著(0)
科研奖励(0)
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资助金额:$20.0万
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财政年份:2020
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依托单位:
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批准号:10628046
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资助金额:$36.08万
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批准号:10799036
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资助金额:$7.07万
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批准号:10595802
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资助金额:$2.14万
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批准号:10604372
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资助金额:$41.0万
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财政年份:2020
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批准号:10398965
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资助金额:$41.0万
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Molecular Mechanisms of Myoblast Fusion
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批准号:9450282
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资助金额:$7.98万
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财政年份:2017
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负责人:Elizabeth H Chen
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依托单位:
Dissecting the Mechanisms of Cell-Cell Fusion Using a Cell Culture System
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批准号:9894439
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资助金额:$13.75万
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负责人:Elizabeth H Chen
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依托单位:
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Dissecting the Mechanisms of Cell-Cell Fusion Using A Cell Culture System
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批准号:8441518
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资助金额:$35.22万
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财政年份:2012
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负责人:Elizabeth H Chen
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依托单位:
Dissecting the Mechanisms of Cell-Cell Fusion Using A Cell Culture System
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批准号:8636485
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资助金额:$32.69万
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财政年份:2012
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批准号:8294190
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资助金额:$30.78万
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依托单位:
Dissecting the Mechanisms of Cell-Cell Fusion Using A Cell Culture System
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批准号:8529899
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资助金额:$3.81万
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财政年份:2012
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负责人:Elizabeth H Chen
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批准号:7429799
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批准号:8452598
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财政年份:2006
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资助金额:$30.9万
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海外基金