Novel Endocrine Approaches to Diagnosis & Treatment of Men with Prostate Cancer

新的内分泌诊断方法

• 批准号: nhmrc : 1102752
• 负责人: Prof Gail Risbridger
• 金额: $ 63.74万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-endocrine-approaches-prostate-cancer/662631
• 关键词: Novel; Endocrine; Approaches; Diagnosis; Treatment

Most men are diagnosed with localised prostate cancer, others have advanced disease. Vision: Identify how tumours are insignificant vs aggressive (Aim 1.1 & 1.2). Predict which tumours will progress to incurable disease (Aim 1.3) and how to target them (Aim 1.4). Discover how each patient tumour is different (Aim 2.1) and pre-clinically test new therapies (Aim 2.2). Outcomes: practice changing discoveries that identify novel therapeutic targets & biomarkers improving diagnosis and treatment.

大多数男性被诊断患有局限性前列腺癌，其他人则患有晚期疾病。愿景：确定肿瘤的重要性与侵袭性（目标 1.1 和 1.2）。预测哪些肿瘤将发展为不治之症（目标 1.3）以及如何针对它们（目标 1.4）。了解每位患者肿瘤的不同之处（目标 2.1）并临床前测试新疗法（目标 2.2）。结果：实践改变的发现，确定新的治疗靶点和生物标志物，改善诊断和治疗。