Administrative Core

行政核心

• 批准号: 10264430
• 负责人: ANDREW J SAYKIN
• 金额: $ 54.56万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10264430
• 关键词: Address; Administrator; Alzheimer' s Disease; Alzheimer' s disease model; Alzheimer' s disease related dementia; Collaborations; Dementia; Development; Diagnosis; Disease; Early Diagnosis; Ensure; Etiology; Evaluation; Faculty; Fostering; Funding; Goals; Growth; Indiana; International; Leadership; Mission; Operations Research; Outcome; Participant; Pathogenesis; Prevention; Process; Publications; Research; Research Infrastructure; Research Training; Resources; Role; Strategic Planning; Therapeutic; base; cohesion; cohort; design; innovation; prevent; programs; success; training opportunity

Project Summary – Administrative Core (AC) The role of the Administrative Core (AC) of the Indiana Alzheimer Disease Research Center (IADRC) is to provide strategic planning, management, resources, and oversight for the Center in support of its continued mission. The significance of this role is based on the U.S. National Plan for AD (NAPA), to prevent and effectively treat AD by 2025 through innovative research on etiology, early detection, and therapeutics. To help accomplish these goals the IADRC has proposed four Overall center aims for the IADRC renewal application: (1) Support, enhance, and expand innovative research on AD and related dementias targeting pathogenesis, diagnosis, treatment, and prevention; (2) Provide critical research resources and infrastructure to support existing studies and enable new innovative research, including a well-characterized longitudinally followed cohort of research participants; (3) Strongly support local, regional, and national/international dementia research collaborations to further the goals of the NIA, national ADRC Network, NAPA and related federal priorities; and, (4) Provide educational and training opportunities related to ADRD for learners of all levels, including those with diverse backgrounds and needs. The AC is responsible for overall management and strategic direction of the IADRC. Leadership within the Center and AC has been stable, with Dr. Andrew Saykin serving as the Center Director since 2013. Brad Glazier has long served as IADRC Administrator and Sarah Van Heiden is the new Research Operations Manager. The AC has six specific aims: (1) Overall direction and strategic planning for research on AD and related disorders. The AC will help to leverage existing strengths of programs and faculty and develop new opportunities for scientific growth and impact. It will also foster integration among the cores for thematic cohesion. The AC will coordinate the Executive Committee, including key leaders to advise and help implement the Center goals. (2) Provide administrative support, resource management and oversight functions. (3) Ensure ongoing evaluation and oversight of scientific progress, research and training. (4) Advance the IADRC goals of fostering and expanding innovative research, training and collaborative academic activities related to AD/ADRD. (5) Develop and manage the IADRC Developmental Projects Program, including solicitation of proposals, a robust and impartial review process, and tracking outcome metrics based on external funding and publication; and (6) Serving as an effective interface to important external organizations and promoting collaboration with other regional, national and international AD research initiatives. This includes interaction with the NIA as well as the NACC, NCRAD, ADNI, DIAN, LEADS, ACTC, ADGC/ADSP, AMP-AD, ADMC/ADMP, MODEL-AD, TREAT-AD and other consortia. The IADRC is committed to accomplishing these aims to support and accelerate progress in addressing the challenges of AD and related disorders.

项目摘要 – 行政核心 (AC) 印第安纳阿尔茨海默病研究中心 (IADRC) 行政核心 (AC) 的作用是 为中心提供战略规划、管理、资源和监督，以支持其持续发展 使命。这一作用的重要性基于美国国家 AD 计划 (NAPA)，旨在预防和 通过病因学、早期检测和治疗的创新研究，到 2025 年有效治疗 AD。帮助 为了实现这些目标，IADRC 为 IADRC 续展申请提出了四个总体中心目标： (1) 支持、加强和扩大针对 AD 和相关痴呆症发病机制的创新研究， 诊断、治疗和预防； (2) 提供关键的研究资源和基础设施来支持 现有研究并启用新的创新研究，包括特征明确的纵向跟踪 研究参与者队列； (3) 大力支持地方、区域和国家/国际痴呆症 研究合作，以推进 NIA、国家 ADRC 网络、NAPA 和相关联邦的目标 优先事项； (4) 为各级学习者提供与 ADRD 相关的教育和培训机会， 包括具有不同背景和需求的人。审计委员会负责全面管理和 IADRC 的战略方向。中心和 AC 的领导一直很稳定，安德鲁博士 Saykin 自 2013 年起担任中心主任。Brad Glazier 长期担任 IADRC 管理员和 Sarah Van Heiden 是新任研究运营经理。审计委员会有六个具体目标： (1) 总体目标 AD 及相关疾病的研究方向和战略规划。审计委员会将帮助利用现有的 项目和教师的优势，并为科学发展和影响力创造新的机会。它还将 促进核心之间的整合，以实现主题的凝聚力。审计委员会将协调执行委员会， 包括为中心目标提供建议和帮助实现的主要领导人。 (2) 提供行政支持， 资源管理和监督职能。 (3) 确保对科学的持续评估和监督 进展、研究和培训。 (4) 推进 IADRC 促进和扩大创新研究的目标， 与 AD/ADRD 相关的培训和协作学术活动。 (5) 发展和管理IADRC 发展项目计划，包括征求建议书、健全和公正的审查流程、 并根据外部资金和出版物跟踪结果指标； (6) 发挥有效作用 与重要的外部组织建立联系，促进与其他区域、国家和地区的合作 国际 AD 研究计划。这包括与 NIA 以及 NACC、NCRAD、 ADNI、DIAN、LEADS、ACTC、ADGC/ADSP、AMP-AD、ADMC/ADMP、MODEL-AD、TREAT-AD 等 财团。 IADRC 致力于实现这些目标，以支持和加速在 应对 AD 和相关疾病的挑战。