PCplanner: operationalizing needs-focused palliative care for older adults in intensive

PCplanner：为重症监护室的老年人实施以需求为中心的姑息治疗

• 批准号: 10593156
• 负责人: Christopher Ethan Cox
• 金额: $ 52.07万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-15 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10593156
• 关键词: Academy; Address; Admission activity; Aging; Area; Caregivers; Caring; Cessation of life; Characteristics; Clinical; Clinical Trials; Collaborations; Communication; Communities; Computerized Medical Record; Data; Decision Making; Dementia; Dissemination and Implementation; Elderly; Electronic Health Record; Enrollment; Environment; Family; Family Caregiver; Feedback; Frequencies; Future; Goals; Health; Health Status; Health system; Healthcare; Hospitals; Infrastructure; Institution; Intensive Care Units; Intervention; Interview; Learning; Length of Stay; Life; Measurement; Medical; Medical center; Medicine; Methods; Modeling; Nurses; Outcome; Palliative Care; Participant; Patient Self-Report; Patient-Focused Outcomes; Patients; Physicians; Process; Public Health Informatics; Quality Indicator; Quality of Care; Randomized; Reporting; Research; Research Personnel; Research Priority; Service delivery model; Site; Specialist; Structure; Surgical Intensive Care; Symptoms; System; Technology; Testing; Time; Treatment Efficacy; United States; United States National Institutes of Health; Work; care coordination; care delivery; care providers; clinical care; collaborative care; community setting; digital; efficacy evaluation; efficacy testing; electronic health data; electronic health record system; experience; follow-up; future implementation; health care service; high risk; hospice environment; implementation barriers; implementation context; improved; improved outcome; innovation; insight; interoperability; mobile application; multidisciplinary; older patient; patient oriented; professional atmosphere; prototype; psychological distress; randomized, clinical trials; secondary outcome; shift work; treatment as usual; usability

The quality of intensive care unit (ICU)-based palliative care is highly variable, particularly for the 2 million older adults admitted annually to ICUs. However, improving care quality on a broad scale with the efficient delivery of patient-centered, need-targeted palliative care is challenging because of logistical and technological barriers. To address these care delivery barriers among older ICU patients, we developed a mobile app platform called PCplanner (Palliative Care planner). PCplanner automates the identification of high-risk patients (e.g., dementia, declining health status, poor functioning) by directly capturing data from electronic health record (EHR) systems, cultivates family engagement with supportive information and a digital system for self-report of actual needs, and facilitates the delivery of care to those with a high burden of need by coordinating collaboration between ICU teams and palliative care specialists. In pilot comparison to a standard palliative care control, the intervention reduced unmet needs, psychological distress, and length of stay and increased goal concordant care, communication, and hospice utilization. While these data are compelling, an efficacy evaluation of PCplanner is needed. Therefore, we propose to enroll 250 patients, 270 family caregivers, and 215 physicians and nurses from academic and community settings in a 5-year project with 3 aims: (1) Optimize the fully realized PCplanner platform’s usability for older adults, (2) Test the efficacy of PCplanner-augmented collaborative palliative care vs usual care in a randomized clinical trial (RCT) with 3-month follow up, and (3) Explore family caregiver and clinician experiences using mixed methods to understand intervention mechanisms as well as implementation barriers within diverse case contexts. We hypothesize that compared to usual care, PCplanner will reduce family caregivers’ unmet needs and psychological distress, increase the frequency of goal concordant treatment among older adult patients, and reduce hospital length of stay. PCplanner represents a potentially transformative, paradigm-changing approach to delivering scalable personalized ICU-based palliative care for older adults: it acts as infrastructure for a replicable collaborative care model, provides a state of the art technological build that enables real-time direct data capture from any hospital’s EHR (i.e., interoperability), and automates the measurement of patient- / family-centered outcomes and quality indicators—all areas that are lacking in current practice. This theoretically grounded project’s numerous technological and conceptual innovations address research priorities detailed by the NIH (Palliative Care Priorities Workgroup), the Office of the National Coordinator (Connecting Health and Care for the Nation Roadmap), and the National Academy of Medicine (Vital Directions for Health Care Services initiative). We can perform this research successfully because of our multidisciplinary team’s expertise and the enthusiastic support of our institution and its clinicians.

重症监护室（ICU）为基础的姑息治疗的质量是高度可变的，特别是对于200万 每年入住ICU的老年人。然而，在广泛的范围内提高护理质量， 有效地提供以患者为中心，以需求为目标的姑息治疗是具有挑战性的，因为后勤和 技术壁垒。为了解决老年ICU患者的这些护理障碍，我们开发了 一个名为PCplanner（姑息治疗计划者）的移动的应用平台。PCplanner自动识别 高风险患者（例如，痴呆、健康状况下降、功能不良）， 从电子健康记录（EHR）系统，培养家庭参与与支持信息 以及一个自我报告实际需求的数字系统，并促进向高血压患者提供护理。 通过协调ICU团队和姑息治疗专家之间的合作，减轻需求负担。在试点 与标准姑息治疗对照组相比，干预减少了未满足的需求，心理 痛苦，住院时间和增加的目标一致的护理，沟通和临终关怀的利用。 虽然这些数据令人信服，但需要对PCplanner进行疗效评估。所以我们 计划招募250名患者，270名家庭护理人员和215名医生和护士， 社区设置在一个5年的项目，有3个目标：（1）优化完全实现的PCplanner平台的 老年人的可用性，（2）测试PCplanner增强的协作姑息治疗与 随机临床试验（RCT）中的常规护理，随访3个月;（3）探索家庭护理者 临床医生使用混合方法了解干预机制的经验， 不同案件背景下的执行障碍。我们假设与常规护理相比， PCplanner将减少家庭照顾者未满足的需求和心理困扰，增加频率 老年患者的目标一致性治疗，并减少住院时间。 PCplanner代表了一种潜在的变革性的、改变范式的方法， 老年人基于ICU的个性化姑息治疗：它作为可复制的基础设施 协作护理模式，提供了一个最先进的技术建设，使实时直接数据 从任何医院的EHR捕获（即，互操作性），并自动测量患者- / 以家庭为中心的成果和质量指标-所有这些领域都是目前实践中缺乏的。这 理论上有基础的项目的许多技术和概念创新解决研究 由NIH（姑息治疗优先事项工作组），国家协调员办公室详细说明的优先事项 （连接健康和护理的国家路线图），和国家医学科学院（重要 卫生保健服务倡议方向）。我们能够成功地进行这项研究是因为我们的 这一切都得益于多学科团队的专业知识以及我们机构及其临床医生的热情支持。

项目成果

Operationalizing needs-focused palliative care for older adults in intensive care units: Design of and rationale for the PCplanner randomized clinical trial.

• DOI: 10.1016/j.cct.2020.106163
• 发表时间: 2020-11
• 期刊: Contemporary clinical trials
• 影响因子: 2.2
• 作者: Cox CE;Olsen MK;Casarett D;Haines K;Al-Hegelan M;Bartz RR;Katz JN;Naglee C;Ashana D;Gilstrap D;Gu J;Parish A;Frear A;Krishnamaneni D;Corcoran A;Docherty SL
• 通讯作者: Docherty SL