Amazonian Center of Excellence in Malaria Research

摘要 亚马逊 ICEMR 的行政核心将为监督所有职能提供基础设施 中心活动。核心 A 的重点是确保项目之间的无缝通信 以及生物统计/数据管理核心 B，与其他 ICEMR 以及 NIAID 项目工作人员。 行政核心将协调三个科学项目与数据管理和 生物统计核心（核心 B），提供一个有凝聚力和协同作用的结构，以确保亚马逊流域 ICEMR 活动最大限度地提高了 ICEMR 计划的科学影响。核心 A 董事将提供 科学和行政领导力，以实现和最大限度地促进跨项目组织 所有研究项目和核心 B 之间的学科互动。因此，核心 A 将提供 科学监督与高效、透明、合规的行政治理（人性化）相结合 主题、动物主题、生物危害、资源共享）关于财政和资源管理 NIH 提供资金。该核心将设在加州大学圣地亚哥分校的 ICEMR 办公室 项目总监约瑟夫·维内茨博士。加州大学圣地亚哥分校将自行管理拨款并与所有机构进行分包 参与机构根据NIH和加州大学的审核标准。加州大学圣地亚哥分校将 负责购买主要设备并运送到共享实验室资源核心 Universidad Peruana Cayetano Heredia，并将代表项目和核心进行其他购买，如果 定价有优势。 这些目标将通过以下具体目标来实现： 1) 促进合作和 通过优化沟通协调 ICEMR 关键人员； 2）组织沟通 与其他网络 ICEMR 和 NIAID 项目工作人员合作，以优化 活动和项目，包括定期会议和电话会议； 3）协调财政管理， 项目及数据管理和生物统计用品的分包、订购和运输 核心B； 4）协调科学顾问组的后勤工作，包括住宿、交通和场地； 5) 在 与 NIH 项目工作人员协调，组织年度网络会议并协调旅行物流 亚马逊 ICEMR 参与者； 6) 协调特别项目的所有行政方面；至 协调、监督和维护所有人类受试者保护协议和批准、生物危害 认证、脊椎动物保护、协议和批准； 8) 协调所有报告 项目和核心领导者负责年度、非竞争性更新以及中期和报告的准备/报告 年度科学顾问小组会议； 9) 支持亚马逊流域的研究能力建设 ICEMR 将为推进中心的整合做出贡献。

Abstract The Administrative Core for the Amazonia ICEMR will provide infrastructure for overseeing all functions of the Center activities. A key emphasis of Core A is to ensure seamless communications among the Projects and the Biostatistics/Data Management Core B, with other ICEMRs, and with NIAID Program Staff. The Administrative Core will coordinate the three Scientific Projects with the Data Management and Biostatistics Core (Core B), providing a cohesive and synergizing structure to ensure that the Amazonia ICEMR activities maximize the scientific impact of the ICEMR program. The Core A Director will provide scientific and administrative leadership to enable and maximize program organization that promotes cross- discipline interactions among all of the Research Projects and the Core B. Core A will therefore provide scientific oversight combined with efficient, transparent and compliant administrative governance (human subjects, animal subjects, biohazards, resource sharing) with regard to fiscal and resource management of NIH-provided funds. This core will be based at the University of California, San Diego in the offices of ICEMR Program Director, Dr. Joseph Vinetz. UCSD will administer the grant itself and carry out subcontracting with all participating institutions according to NIH and University of California auditing standards. UCSD will be responsible for purchase of major equipment and shipment to Shared Laboratory Resource Core at Universidad Peruana Cayetano Heredia, and will make other purchases on behalf of the Projects and Cores if pricing is advantageous. These goals will be accomplished through the following Specific Aims: 1) To promote collaboration and coordination among ICEMR key personnel through optimized communications; 2)To organize communications with other network ICEMRs and with NIAID program staff to optimize collaboration and coordination of activities and projects including periodic meetings and conference calls; 3) To coordinate fiscal management, subcontracting, ordering and shipping of supplies for projects and the Data Management and Biostatistics Core B; 4) To coordinate logistics of the Scientific Advisory Group, including lodging, travel and venue; 5) In coordination with NIH program staff, to organize an annual network meeting and coordinate travel logistics for Amazonia ICEMR participants; 6) To coordinate all administrative aspects of the Special Projects; To coordinate, supervise and maintain all Human Subjects Protections protocols and approvals, biohazards certifications, and vertebrate animal protections, protocols and approvals; 8) To coordinate reports of all Project and Core Leaders for annual, non-competing renewals and preparation/reporting of interim and annual Scientific Advisory Group meetings; and 9) To support research capacity building in the Amazonia ICEMR to contribute to advance the Center’s integration.