Novel inhalation formulation of bacteriophages against ‘superbugs’ causing respiratory infections

针对引起呼吸道感染的“超级细菌”的新型噬菌体吸入制剂

• 批准号: nhmrc : 1140617
• 负责人: Dr Kaye Morgan
• 金额: $ 38.11万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-inhalation-formulation-respiratory-infections/1319272
• 关键词: Novel; inhalation; formulation; bacteriophages; against

Emergence of superbugs has led to life-threatening respiratory infections that are resistant to most antibiotics. There is an urgent need for alternative treatments not relying on antibiotics. Bacteriophages (or ‘bacteria eaters’) are natural predators of bacteria and are unaffected by antibiotic resistance. This multi-disciplinary project will develop novel therapeutics using inhaled bacteriophages against bacterial infections in the lungs.

超级细菌的出现导致了危及生命的呼吸道感染，这些感染对大多数抗生素都有抗药性。迫切需要不依赖抗生素的替代疗法。噬菌体（或“噬菌体”）是细菌的天敌，不受抗生素耐药性的影响。这个多学科的项目将开发新的治疗方法，使用吸入噬菌体对抗肺部细菌感染。