CARDIOVASCULAR OUTCOMES RESEARCH TRAINING PROGRAM

心血管结果研究培训计划

• 批准号: 10606471
• 负责人: JOHN A SPERTUS
• 金额: $ 41.18万
• 依托单位: UNIVERSITY OF MISSOURI KANSAS CITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10606471
• 关键词: Cardiovascular system; Outcomes Research; Training Programs

Project Summary/Abstract As the leading cause of death and disability in the United States, cardiovascular disease has benefitted from immense research investments to improve the care of afflicted patients. However, the application of this knowledge in routine clinical practice has been variable and the evaluation of more patient-centered outcomes, including patients’ symptoms, function and quality of life, are desperately needed. Not only do these knowledge gaps limit the potential for US healthcare to improve, but evolving changes in reimbursement from a volume- to value-based payment models have created an unparalleled demand for cardiovascular outcomes researchers. This renewal application seeks to continue a highly successful program for training post-doctoral scholars to independently perform clinically-oriented outcomes research. It extends and improves the University of Missouri- Kansas City (UMKC)’s outcomes research training program, which is unique in the Midwest and serves as a central unifying research program for our region. The 2-year training program has 3 synergistic components: 1) a basic foundation of in clinical research (including a Masters degree in bioinformatics with a clinical research emphasis), 2) specialized skills for outcomes research coupled with academic ‘survival skills’ (our outcomes- based core curriculum), and 3) hands-on research. Hallmarks of the research experiences include multi- disciplinary group mentorship, individualized mentorship to meet each trainee’s needs; access to numerous existing data, as well as clinical populations for primary data collection and implementation; training in entrepreneurship; and highly experienced statistical support. Enhancements planned for the existing program include 1) a more robust collaboration with the University of Missouri system, which is investing in the NextGen Precision Medicine institute and for which our program serves as the central pillar for precision healthcare delivery; 2) increased engagement in clinical trial design and execution; and 3) access to a new community collaboration of 19 regional hospitals innovating healthcare delivery to improve its value (www.kcqvic.org) for deeper exposure to implementation research. Administering the program will be an experienced program director, supported by well-qualified associate and assistant directors and mentors with expertise in economics and decision analysis; large database analysis; bioinformatics; qualitative and implementation research; study design, methodology and statistics; patient and clinician behavior change; community-based participatory research; entrepreneurship; shared medical decision-making and patient-centered research; multi-disciplinary cardiovascular research; disparities research; and risk models and creation of clinical tools, as well as an advisory committee of national leaders. Collectively, our committed team will provide a formal training, mentorship and evaluation program to continue and enhance our prior success in supporting the ability of trainees to make significant contributions to the scientific literature and to embark on successful academic research careers.

项目总结/文摘

项目成果

Global patterns of comprehensive cardiovascular risk factor control in patients with type 2 diabetes mellitus: Insights from the DISCOVER study.

• DOI: 10.1111/dom.14180
• 发表时间: 2021-01
• 期刊: Diabetes, obesity & metabolism
• 作者: Patel KK;Gomes MB;Charbonnel B;Chen H;Cid-Ruzafa J;Fenici P;Hammar N;Ji L;Kennedy KF;Khunti K;Kosiborod M;Pocock S;Shestakova MV;Shimomura I;Surmont F;Watada H;Arnold SV
• 通讯作者: Arnold SV

Outcomes of pediatric patients with COVID-19 and in-hospital cardiopulmonary resuscitation.

• DOI: 10.1016/j.resuscitation.2022.02.018
• 发表时间: 2022-04
• 期刊: Resuscitation
• 影响因子: 6.5
• 作者: El-Zein RS;Chan ML;Su L;Chan PS;American Heart Association's Get With the Guidelines®-Resuscitation Investigators
• 通讯作者: American Heart Association's Get With the Guidelines®-Resuscitation Investigators

Association Between Delays in Time to Bystander CPR and Survival for Witnessed Cardiac Arrest in the United States.

在美国，旁观者进行心肺复苏的时间延迟与目击心脏骤停的生存率之间的关系。

• DOI: 10.1161/circoutcomes.123.010116
• 发表时间: 2024
• 期刊: Circulation. Cardiovascular quality and outcomes
• 作者: Nguyen,DanD;Spertus,JohnA;Kennedy,KevinF;Gupta,Kashvi;Uzendu,AneziI;McNally,BryanF;Chan,PaulS
• 通讯作者: Chan,PaulS

The Impact of De-escalation of Antianginal Medications on Health Status After Percutaneous Coronary Intervention.

经皮冠状动脉介入治疗后抗心绞痛药物降级对健康状况的影响。

• DOI: 10.1161/jaha.117.006405
• 发表时间: 2017
• 期刊: Journal of the American Heart Association
• 影响因子: 5.4
• 作者: Qintar,Mohammed;Towheed,Arooge;Tang,Fengming;Salisbury,AdamC;Ho,PMichael;Grantham,JAaron;Spertus,JohnA;Arnold,SuzanneV
• 通讯作者: Arnold,SuzanneV

Adjusting for Risk Associated With Pediatric and Congenital Cardiac Catheterization: A Report From the NCDR IMPACT Registry.

• DOI: 10.1161/circulationaha.114.014694
• 发表时间: 2015-11-17
• 期刊: Circulation
• 影响因子: 37.8
• 作者: Jayaram N;Beekman RH 3rd;Benson L;Holzer R;Jenkins K;Kennedy KF;Martin GR;Moore JW;Ringel R;Rome J;Spertus JA;Vincent R;Bergersen L
• 通讯作者: Bergersen L