Flexible representation of speech in human auditory cortex
人类听觉皮层中语音的灵活表示
基本信息
- 批准号:10605606
- 负责人:
- 金额:$ 3.35万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-12-01 至 2023-04-30
- 项目状态:已结题
- 来源:
- 关键词:AccentAcousticsAddressAreaAuditoryAuditory areaBehavior ControlBehavioralBehavioral ResearchBrainCategoriesClinicalCodeCognitiveCommunication impairmentComplementCuesDataDimensionsDoctor of PhilosophyEffectivenessElectrocorticogramElectroencephalographyElectrophysiology (science)EngineeringEnvironmentFrequenciesGeneral PopulationGoalsHearingHumanInterventionLaboratoriesLanguageLinguisticsLinkMapsMeasurableMeasuresModelingNeurobiologyNeurologicNeurosciencesNoisePearPopulationPsychophysicsResearchResearch TrainingScalp structureSchizophreniaSensorySignal TransductionSourceSpeechSpeech AcousticsSpeech PerceptionStimulusStructure of superior temporal sulcusSuperior temporal gyrusSurfaceSystemTemporal LobeTestingTheoretical modelTimeTrainingTraining SupportTranslatingUrsidae FamilyVariantWeightWorkautism spectrum disordercareerclear speechclinical applicationcognitive neurosciencecohortcontextual factorsflexibilitygray matterhearing impairmentimprovedinnovationinsightnervous system disorderneural information processingneuromechanismnovelrehabilitation strategyrelating to nervous systemresponsespeech in noisespeech processingspeech recognitiontranslational health science
项目摘要
PROJECT SUMMARY/ABSTRACT
The mapping from acoustics to linguistically relevant speech categories is not fixed; rather, speech recognition
adapts to listening context. For example, the utterances bear and pear differ by as many as 16 spectrotemporal
acoustic dimensions. The relative importance (i.e., the perceptual weight) of each of these acoustic dimensions
in signaling bear vs. pear changes with contextual factors like whether the listening environment is quiet or
noisy and whether the talker speaks in a native or unfamiliar accent. This flexibility or adaptive plasticity is an
important component of how the brain maintains robust speech perception despite considerable variation in
speech acoustics. Indeed, inflexible sensory processing is implicated as a source of perceptual deficits in both
hearing impairment and neurological disorders. Yet, the neural mechanisms underlying adaptive plasticity in
speech perception are poorly understood. To address this gap, the proposed research will leverage access
deep within human auditory cortex obtained through intracerebral stereotactic electroencephalography (sEEG),
by employing sEEG simultaneously with scalp electroencephalography (EEG) and well-established behavioral
tasks for measuring adaptive plasticity. Aim 1 will invoke adaptive plasticity in speech perception with acoustic
noise or a change in short-term input distributions mimicking an ‘accent’ and will relate behavioral changes in
the perceptual weights of acoustic dimensions relative to baseline (i.e., clear speech) to changes in the neural
response profile across the auditory cortical hierarchy. Aim 2 will quantify the relationships between sEEG and
EEG to establish the extent to which intracerebral signatures of adaptive plasticity relate to scalp EEG
signatures measurable in the general population; this will also facilitate region-specific interpretation of EEG.
The work will provide novel insight into the cortical mechanisms of adaptive plasticity in speech perception,
with implications for neurobiological models and clinical applications. Our innovative combination of
simultaneous scalp EEG with spatially specific, high signal-to-noise ratio sEEG will create a highly informative
link across noninvasive and intracranial electrophysiology. Project completion also will provide the applicant
with training in cognitive neuroscience of speech perception, intracerebral electrophysiology, and approaches
to effectively integrate intracerebral and scalp EEG. This training will complement her strong
engineering/quantitative background and Ph.D. training in auditory temporal coding, scene analysis, and EEG.
This will advance her goal of undertaking a successful independent academic research career in the
neuroscience of human audition and speech perception.
项目总结/文摘
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Vibha Viswanathan其他文献
Vibha Viswanathan的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Vibha Viswanathan', 18)}}的其他基金
Neurophysiological Mechanisms of Speech Intelligibility in Noise - A Quantitative Framework
噪声中言语清晰度的神经生理学机制 - 定量框架
- 批准号:
9788035 - 财政年份:2018
- 资助金额:
$ 3.35万 - 项目类别:
相似海外基金
Nonlinear Acoustics for the conditioning monitoring of Aerospace structures (NACMAS)
用于航空航天结构调节监测的非线性声学 (NACMAS)
- 批准号:
10078324 - 财政年份:2023
- 资助金额:
$ 3.35万 - 项目类别:
BEIS-Funded Programmes
ORCC: Marine predator and prey response to climate change: Synthesis of Acoustics, Physiology, Prey, and Habitat In a Rapidly changing Environment (SAPPHIRE)
ORCC:海洋捕食者和猎物对气候变化的反应:快速变化环境中声学、生理学、猎物和栖息地的综合(蓝宝石)
- 批准号:
2308300 - 财政年份:2023
- 资助金额:
$ 3.35万 - 项目类别:
Continuing Grant
University of Salford (The) and KP Acoustics Group Limited KTP 22_23 R1
索尔福德大学 (The) 和 KP Acoustics Group Limited KTP 22_23 R1
- 批准号:
10033989 - 财政年份:2023
- 资助金额:
$ 3.35万 - 项目类别:
Knowledge Transfer Partnership
User-controllable and Physics-informed Neural Acoustics Fields for Multichannel Audio Rendering and Analysis in Mixed Reality Application
用于混合现实应用中多通道音频渲染和分析的用户可控且基于物理的神经声学场
- 批准号:
23K16913 - 财政年份:2023
- 资助金额:
$ 3.35万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Combined radiation acoustics and ultrasound imaging for real-time guidance in radiotherapy
结合辐射声学和超声成像,用于放射治疗的实时指导
- 批准号:
10582051 - 财政年份:2023
- 资助金额:
$ 3.35万 - 项目类别:
Comprehensive assessment of speech physiology and acoustics in Parkinson's disease progression
帕金森病进展中言语生理学和声学的综合评估
- 批准号:
10602958 - 财政年份:2023
- 资助金额:
$ 3.35万 - 项目类别:
The acoustics of climate change - long-term observations in the arctic oceans
气候变化的声学——北冰洋的长期观测
- 批准号:
2889921 - 财政年份:2023
- 资助金额:
$ 3.35万 - 项目类别:
Studentship
Collaborative Research: Estimating Articulatory Constriction Place and Timing from Speech Acoustics
合作研究:从语音声学估计发音收缩位置和时间
- 批准号:
2343847 - 财政年份:2023
- 资助金额:
$ 3.35万 - 项目类别:
Standard Grant
Flow Physics and Vortex-Induced Acoustics in Bio-Inspired Collective Locomotion
仿生集体运动中的流动物理学和涡激声学
- 批准号:
DGECR-2022-00019 - 财政年份:2022
- 资助金额:
$ 3.35万 - 项目类别:
Discovery Launch Supplement
Collaborative Research: Estimating Articulatory Constriction Place and Timing from Speech Acoustics
合作研究:从语音声学估计发音收缩位置和时间
- 批准号:
2141275 - 财政年份:2022
- 资助金额:
$ 3.35万 - 项目类别:
Standard Grant














{{item.name}}会员




