COVID-19 Animal Testing Capacity

COVID-19 动物测试能力

• 批准号: 10609727
• 负责人: Eman Anis
• 金额: $ 1.93万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10609727
• 关键词: COVID; 19; Animal; Testing; Capacity

PROJECT SUMMARY /ABSTRACT COVID-19 animal testing capacity Severeacute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of Coronavirusdisease 19 (COVID-19), which is an ongoing global health concern. The widespreadnature of this zoonotic disease and the susceptibilityof some animal species includingcompanion animals (cats and dogs), zoo animals, farmed mink, and wildlifeto infection emphasizes the need of expanding SARS-CoV-2 testing in animals. Understanding the extent of SARS-CoV-2 infections of domestic and wild animals would provide the necessary evidence to better assess the implications of widespread human SARS-CoV-2 infections for animal health and welfare. Our lab already has an established protocol for testing animal samples for SARS-CoV-2 using a real-time PCR panel, however, the presence of a single PCR workstation to set up the PCR reagents for all the PCR diagnostic assays performed in our laboratory limits our ability to expand our animal SARS-CoV-2 diagnostic and surveillance testing capacity. We propose to purchase a PCR workstation and laboratory refrigerator. This additional equipment will allow us to conduct large scale surveillance for detecting SARS-CoV- 2 infections among wild and domestic animals.

项目总结/摘要 COVID-19动物试验能力 严重急性呼吸道综合征冠状病毒2（SARS-CoV-2）是引起 冠状病毒病19（COVID-19）是一个持续的全球健康问题。的 这种人畜共患病的传染性和某些动物物种的易感性 包括伴侣动物（猫和狗），动物园动物，养殖水貂和野生动物， 感染强调了扩大SARS-CoV-2动物试验的必要性。了解 SARS-CoV-2感染家畜和野生动物的程度将提供必要的 更好地评估广泛的人类SARS-CoV-2感染对 动物健康和福利。我们的实验室已经有了一套测试动物样本的既定规程 然而，对于使用实时PCR面板的SARS-CoV-2， 工作站设置PCR试剂，用于在我们的 实验室限制了我们扩大动物SARS-CoV-2诊断和监测的能力 测试能力。我们建议购买PCR工作站和实验室冰箱。这 额外的设备将使我们能够进行大规模的监测，以检测SARS-CoV， 野生动物和家养动物中的2例感染。