Substance Use Scientific Working Group

药物使用科学工作组

• 批准号: 10609486
• 负责人: JOY Marie SCHMITZ
• 金额: $ 3.46万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-23 至 2026-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10609486
• 关键词: AIDS prevention; Acceleration; Acquired Immunodeficiency Syndrome; Affect; Alcohols; Area; Basic Science; Biomedical Research; Biostatistics Core; Clinical; Cocaine; Collaborations; Communities; Complex; Development; Emergency department visit; Ensure; Epidemic; Evaluation; Fostering; Funding; Funding Opportunities; Goals; Grant; HIV; Health; Health Sciences; Homeless Youth; Individual; Infrastructure; Institution; International; Lead; Leadership; Link; Marijuana; Medicine; Mental Health; Outcome; Persons; Pilot Projects; Policies; Procedures; Public Health; Research; Research Institute; Research Personnel; Research Priority; Research Project Grants; Research Support; Resources; Risk Factors; School Nursing; Services; Societies; Substance Addiction; Substance Use Disorder; Talents; Texas; Universities; Work; addiction; cofactor; college; high risk; improved; innovation; interest; medical schools; member; methamphetamine use; novel; opioid use; overdose death; programs; substance use; substance use treatment; success; transmission process; trend; viral transmission; working group; young adult

PROJECT SUMMARY - SUBSTANCE USE SCIENTIFIC WORKING GROUP The Texas Developmental Center for AIDS Research (D-CFAR) is based at Baylor College of Medicine (Baylor) and University of Texas Health Science Center at Houston (UTHealth) and the Texas Biomedical Research Institute (TxBiomed) in San Antonio. It will establish a Substance Use Scientific Working Group (SU- SWG). Substance use trends in the state of Texas are similar to the nation as a whole in showing an increase in opioid use and related emergency department visits and overdose deaths in recent years. Equally concerning are recent trends in the use of methamphetamine, marijuana, cocaine, and alcohol. Substance use and HIV are inextricably linked. Substance use is a well-established risk factor for transmission of the virus. For people living with HIV, substance use and addiction can hasten the progression of HIV and its consequences. Despite its significant impact on HIV, the intersection of substance use and HIV has been an underdeveloped research area, especially in areas of the US with weaker substance use treatment infrastructures like Texas. The proposed Texas D-CFAR SU-SWG will foster a robust research program in three areas that align with the proposed D-CFAR to fill this gap: 1) substance use as a co-factor for transmission of HIV; 2) impact of substance use on progression of HIV and its consequences; 3) novel treatment approaches for HIV prevention and treatment for individuals who use substances. The SU-SWG will support research in these areas by developing key resources, services, pilot funding opportunities, and by fostering discussions and collaborations between Texas D-CFAR members. To achieve its goals, the SU-SWG will: 1) Work with the proposed Cores and Core services to develop and support substance use as a critical area of research focus for ending HIV and optimizing HIV health in Texas. 2) Inform the Texas D-CFAR community about ongoing and future research on the intersection of substance use and HIV, both at our D-CFAR, nationally, and internationally. 3) Inform the D-CFAR community about external funding opportunities on substance use, provide pilot project funding opportunities through the Developmental Core, and catalyze collaborations. 4) Expand the SU-SWG by opening membership to substance use and HIV researchers and trainees at other Texas institutions. To achieve these aims, the D-CFAR has assembled a group of established and early stage investigators in both HIV and substance use to bring together in the SU-SWG to foster research in the intersection of these two epidemics. The SU-SWG includes persons with deep connections to the community and local public health officials as well as academicians who have developed and lead innovative programs to deliver substance use treatments. The SU-SWG leadership, in collaboration with the D-CFAR leadership, has identified a comprehensive 5-year action plan, set of activities, policies and procedures and evaluation metrics to ensure success. This activity organized by the SU-SWG will accelerate efforts to end HIV and improve the health of people with HIV in Texas and beyond.

项目摘要--物质使用科学工作组 得克萨斯州艾滋病研究发展中心(D-CFAR)设在贝勒医学院 (贝勒)和德克萨斯大学休斯顿健康科学中心(UTHealth)和德克萨斯生物医学 圣安东尼奥的研究机构(TxBimed)。它将建立一个物质使用科学工作组(SU- SWG)。德克萨斯州的药物使用趋势与全国总体相似，显示出增加的趋势 近年来，阿片类药物的使用和相关的急诊科就诊和过量死亡。同样 令人担忧的是最近甲基苯丙胺、大麻、可卡因和酒精的使用趋势。物质使用 和艾滋病毒有着千丝万缕的联系。使用药物是传播病毒的一个公认的风险因素。为 艾滋病毒携带者、药物使用和成瘾会加速艾滋病毒及其后果的发展。 尽管它对艾滋病毒有重大影响，但药物使用和艾滋病毒的交集一直是不发达的 研究领域，特别是在德克萨斯州等物质使用治疗基础设施较弱的美国地区。 拟议的德克萨斯州D-CFAR SU-SWG将在三个领域培养一个强有力的研究计划，这些领域与 拟议的D-CFAR以填补这一空白：1)使用物质作为艾滋病毒传播的辅助因素；2)影响 物质使用对艾滋病毒进展及其后果的影响；3)预防艾滋病毒的新治疗方法 以及对使用药物的个人的治疗。特别工作组将通过以下方式支持这些领域的研究 开发关键资源、服务、试点筹资机会，并通过促进讨论和合作 在德克萨斯州D-CFAR成员之间。为了实现其目标，特设局将：1)与拟议的核心合作 和核心服务，以开发和支持物质使用，将其作为结束艾滋病毒的关键研究重点领域 以及优化德克萨斯州的艾滋病毒健康。2)告知德克萨斯州D-CFAR社区正在进行的和未来的情况 在我们的D-CFAR上，在全国和国际上，研究药物使用和艾滋病毒的交叉点。3) 向D-CFAR社区通报物质使用方面的外部资金机会，提供试点项目 通过发展核心为机会提供资金，并促进合作。4)扩展SU-SWG 通过向物质使用和艾滋病毒研究人员以及德克萨斯州其他机构的实习生开放会员资格。至 为了实现这些目标，D-CFAR在两个地区召集了一批成熟的和早期的调查人员 艾滋病毒和物质使用在SU-SWG中汇聚在一起，以促进这两个方面的交叉研究 流行病。SU-SWG包括与社区和当地公共卫生有很深联系的人 开发和领导创新项目以提供物质使用的官员和院士 治疗。特遣部队领导层与民盟领导层合作，确定了一个 全面的五年行动计划、一套活动、政策和程序以及评估指标，以确保 成功。这项由苏-SWG组织的活动将加快努力，结束艾滋病毒，改善人民的健康 得克萨斯州和其他地方的艾滋病毒携带者。