Substance Use and HIV Prevention Research in Minority Communities Training Program

摘要 该申请旨在继续资助少数民族药物使用和艾滋病毒预防研究 社区计划（SUHPR）在加州大学旧金山弗朗西斯科（UCSF）。SUHPR指出， 迫切需要促进临床预防研究，减少边缘化社区的健康差距 在那里药物使用是一个至关重要的公共卫生问题。SUHPR还旨在增加科学家的数量 获得国家卫生研究院资助的不同背景的人具体而言，该委员会将： 1)提高客座教授（VP）学员进行跨学科临床研究的能力， 阐明并解决边缘化社区药物使用与艾滋病毒之间的联系， NIDA和NIH艾滋病研究办公室（OAR）的优先事项; 2)为试点研究提供资金，为赠款提案提供初步数据; 3)协助发展副总裁的研究事业和技能，以及概念化，写作，提交， 修订和重新提交NIH拨款，重点关注药物使用、艾滋病毒预防和艾滋病毒护理 通过指导会议、研讨会、网络研讨会和同行网络取得成果; 4)通过同行评审和写作来维持和扩大前副总裁的研究项目 务虚会，同时利用他们作为同行评审员，导师和合作者的经验。 目标1 - 3将通过参与加州大学旧金山分校为期三年的夏季密集计划的副总裁来实现。 每个副总裁将访问加州大学旧金山分校六个星期，每年夏天三个夏天，参加艾滋病研讨会， 物质使用的研究，方法，并授予写作。在第一个夏天，教师导师和同行副总裁将 协助每个副总裁将他们的研究想法转化为可行的研究应用（目标1），制定计划， 他们的试点研究（目标2），并开始起草一份NIH拨款申请（目标3）。副总裁随后将启动试点研究 在第一个夏天之后的学年。在第二个夏天，副总裁将完成并提交他们的 国家卫生研究院的拨款提案。在第二个夏天之后，副总裁将在科学大会上展示试点研究结果。 会议和出版提交的草稿。在第三个夏天，副总裁将修改和 重新提交提案以回应NIH评审员的反馈。如果VP在第三次之前获得NIH资助， 夏天，副总裁计划将指导他们在研究启动活动，以提高严谨性和可能的成功， 国家卫生研究院资助的研究在夏季之间（学年期间），教师导师将与 至少每月一次的副总裁，辅以网络研讨会和虚拟写作务虚会。为了加强这项深入的研究， 教育经验，SUHPR计划将提供科学的同行评审和咨询后，第三次 夏季，以帮助来自不同背景的副总裁留在研究管道，并扩大他们的创新 药物使用和艾滋病毒研究方案（目标4）。我们会邀请成功的前副总裁进行同行评审， 指导和与现任副总裁的合作活动。

ABSTRACT This application seeks continuation of funding for the Substance Use and HIV Prevention Research in Minority Communities program (SUHPR) at the University of California San Francisco (UCSF). SUHPR addresses the urgent need to promote clinical prevention research and reduce health disparities in marginalized communities where substance use is a crucial public health concern. SUHPR also aims to increase the number of scientists from diverse backgrounds who attain NIH funding. Specifically, SUHPR will: 1) Increase visiting professor (VP) trainees' capacity to conduct interdisciplinary clinical research that elucidates and addresses the links between substance use and HIV in marginalized communities in line with NIDA and the NIH Office of AIDS Research (OAR) priorities; 2) Fund pilot studies to provide preliminary data for grant proposals; 3) Assist in the development of VP research careers and skills and the conceptualization, writing, submission, revision, and resubmission of NIH grants that focus on substance use, HIV prevention, and HIV care outcomes, via mentoring meetings, seminars, webinars, and peer networking; and 4) Sustain and expand the research programs of former VPs by engaging them via peer reviews and writing retreats, while leveraging their experience as peer reviewers, mentors, and collaborators. Aims 1-3 will be accomplished through VPs participating in a three-year summer intensive program at UCSF. Each VP will visit UCSF for six weeks per summer for three summers, attending seminars on HIV and substance use research, methods, and grant writing. In the first summer, faculty mentors and peer VPs will assist each VP to develop their research ideas into feasible research applications (Aim 1), develop a plan for their pilot study (Aim 2), and begin drafting an NIH grant proposal (Aim 3). VPs will then initiate the pilot studies during the academic year following the first summer. In the second summer, VPs will complete and submit their NIH grant proposals. Following the second summer, VPs will present pilot study findings at scientific conferences and draft manuscripts for publication submission. During the third summer, VPs will revise and resubmit the proposal in response to NIH reviewer feedback. If VPs receive NIH funding prior to the third summer, the VP program will mentor them in study start-up activities to enhance the rigor and likely success of their NIH-funded studies. Between summers (during the academic year), faculty mentors will communicate with VPs at least monthly, supplemented by webinars and virtual writing retreats. To fortify this intensive research education experience, the SUHPR program will provide scientific peer reviews and consultations after the third summer to help VPs from diverse backgrounds remain in the research pipeline and extend their innovative programs of substance use and HIV research (Aim 4). We will involve successful former VPs for peer reviews, mentoring, and collaboration activities with current VPs.