Regulation and Physiological Roles of Translational Fidelity

翻译保真度的调节和生理作用

基本信息

  • 批准号:
    10617051
  • 负责人:
  • 金额:
    $ 6.48万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2020
  • 资助国家:
    美国
  • 起止时间:
    2020-06-01 至 2025-05-31
  • 项目状态:
    未结题

项目摘要

PROJECT SUMMARY The goal of this project is to enhance the diversity of the biomedical research workforce by training a Ph.D. student from an underrepresented minority group (African Americans) and facilitate her development towards an independent scientist in the field of microbiology and pathogen-host interactions. The student will receive rigorous training to study pathogen-host interactions, protein synthesis, bacterial genetics, and microbial stress responses. Translational fidelity is critically maintained throughout evolution to ensure accurate protein synthesis. However, the role of translational fidelity in pathogen-host interactions remains largely unknown. The proposed training aims at studying how translational fidelity affects Salmonella-macrophage interactions. During the training, the student will (a) develop important research skills covering bacterial genetics, single-cell analyses, cell culture, molecular biology, and biochemistry, (b) enhance her skills of critical reading, thinking, presentation, and writing, and (c) strengthen her ability of proper experimental design and development of hypothesis-driven research. In addition, the student will have the opportunities to further career development by engaging in presenting research at local/national/international meetings, mentoring students, and taking professional training courses. The outcomes of the proposed training will help elucidate the role of translational fidelity in pathogen-host interactions using Salmonella as a model, further the student’s development as an independent microbiologist, expand the student’s professional network, and promote diversity in the workforce of microbiology and infectious diseases.
项目总结

项目成果

期刊论文数量(0)
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专利数量(0)

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JIQIANG LING其他文献

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{{ truncateString('JIQIANG LING', 18)}}的其他基金

Regulation and Physiological Roles of Translational Fidelity
翻译保真度的调节和生理作用
  • 批准号:
    10619629
  • 财政年份:
    2020
  • 资助金额:
    $ 6.48万
  • 项目类别:
Regulation and Physiological Roles of Translational Fidelity
翻译保真度的调节和生理作用
  • 批准号:
    10725047
  • 财政年份:
    2020
  • 资助金额:
    $ 6.48万
  • 项目类别:
Regulation and Physiological Roles of Translational Fidelity
翻译保真度的调节和生理作用
  • 批准号:
    10406906
  • 财政年份:
    2020
  • 资助金额:
    $ 6.48万
  • 项目类别:
Regulation and Physiological Roles of Translational Fidelity
翻译保真度的调节和生理作用
  • 批准号:
    10166886
  • 财政年份:
    2020
  • 资助金额:
    $ 6.48万
  • 项目类别:
Studies of Aminoacyl-tRNA Synthetase Mutations Causing Progressive Microcephaly
氨酰基-tRNA 合成酶突变导致进行性小头畸形的研究
  • 批准号:
    9751423
  • 财政年份:
    2018
  • 资助金额:
    $ 6.48万
  • 项目类别:
Physiological impact of reduced fidelity in protein synthesis
蛋白质合成保真度降低的生理影响
  • 批准号:
    8932246
  • 财政年份:
    2015
  • 资助金额:
    $ 6.48万
  • 项目类别:

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Molecular and Genetic Signatures of Perturbed Diabetic Pathways with Hepatitis C Virus infection and Co-morbidity Risks in African American Population
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