Surveillance of SARS-CoV-2 Variants in Hawaii

夏威夷 SARS-CoV-2 变种的监测

• 批准号: 10612287
• 负责人: Robert Alan Nichols
• 金额: $ 6.5万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-30 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10612287
• 关键词: Advisory Committees; Applications Grants; Basic Science; Bioinformatics; Biomedical Research; Biometry; Career Mobility; Communication; Communities; Data; Data Analyses; Development; Education; Educational Curriculum; Educational process of instructing; Educational workshop; Faculty; Fellowship; Funding; Funding Mechanisms; Funding Opportunities; Genomics; Goals; Grant; Hawaii; Health; Health Benefit; Immersion; Individual; Infrastructure; Institution; Internships; Laboratories; Lead; Leadership; Learning; Mentors; Metagenomics; Molecular Medicine; National Institute of General Medical Sciences; Natural Products; Participant; Pathway interactions; Personal Satisfaction; Pilot Projects; Productivity; Program Development; Program Research Project Grants; Proteomics; Public Health; Research; Research Activity; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Resource Development; Resources; Role; Science; Scientist; Seasons; Solid; Structure; Students; Technical Expertise; Technology; Time; Training; Training Programs; Training and Education; Universities; Workforce Development; base; bioinformatics resource; career; career development; catalyst; college; community college; data management; epigenomics; experience; faculty mentor; health science research; improved; informatics tool; innovation; instrumentation; interest; laboratory experience; meetings; metabolomics; multidisciplinary; next generation; next generation sequencing; outreach; outreach program; programs; recruit; research and development; skills training; student participation; synergism; transcriptomics; undergraduate education; undergraduate research experience; undergraduate student; volunteer

PROJECT SUMMARY The Hawaii Statewide Research and Education Partnership (HiSREP) comprises a network of nearly all of the institutions of higher learning in the state of Hawaii, specifically 4 primarily undergraduate institutions (PUIs), 1 University of Hawaii (UH) college and 4 UH community colleges under the management of the lead R1 institution, the University of Hawaii at Manoa. In the previous grant cycle, INBRE III focused on strengthening the research community and infrastructure at the partner institutions outside of the lead institution. This was accomplished through a tightly coordinated leadership team overseeing an integrated program of support for new laboratory construction under Alterations & Renovation funding, acquisition of new instrumentation, funding for junior investigator research and undergraduate student research experiences paired with outreach and multi-level mentoring. This resulted in substantial expansion of the research base, stronger student engagement leading to a near doubling in student participants, and new initiatives in career advancement. In INBRE IV, HiSREP will continue the development of emerging investigators, but will widen the reach of the network to all levels of biomedical research scientists through a new array of competitive granting mechanisms including teaching-postdoctoral fellowships, pilot projects, new initiatives and team-based collaborative grants through a Developmental Research Project Program (DRPP). Research under HiSREP will be guided by two key themes, Natural Products and Molecular Medicine, which emphasize notable strengths in the biomedical research community in Hawaii. In addition, HiSREP will support a reorganized Bioinformatics Core as a centralized resource across the state to provide education on bioinformatics, aid with research design, technical expertise including development of new informatics tools, data management and analysis. The Bioinformatics Core will promote community synergy for researchers and students through one-on-one, group, workshop, course and online interactions, the latter through a real-time research community portal. The student research program under the PATHway to Biomedical Careers will look to embrace a wider range of undergraduates by emphasizing collaborative group projects through volunteer, intern, scholar and returning researcher opportunities, including partnerships with complementary undergraduate research programs, while maintaining focus on individual career development through skill training, practical mentoring sessions, extended resources and workforce development. In addition, PATHway will develop proactive advanced training for laboratory supervisors to increase research sophistication as well as opportunity statewide, leading to increased capacity. It will also ultimately enhance undergraduate education through incorporation of research activity into the basic science curriculum. Overall, HiSREP will serve as a catalyst for advancement of the research scientist pipeline with the ultimate goal of elevating the ability of the biomedical research community to make new and important discoveries for improving health and well-being in the state of Hawaii.

项目摘要 夏威夷全州研究和教育伙伴关系（HiSREP）包括一个几乎所有的网络， 夏威夷州的高等教育机构，特别是4所主要的本科院校（PUI），1所 夏威夷大学（UH）学院和4所UH社区学院，由领导R1管理 机构，马诺阿的夏威夷大学。在上一个赠款周期，机构间规划和研究所第三期的重点是加强 牵头机构以外的伙伴机构的研究界和基础设施。这是 通过一个密切协调的领导小组监督一个综合的支持方案， 在改建和翻新资金下建造新的实验室，购置新的仪器， 资助初级研究人员的研究和本科生的研究经验与推广配对 和多层次的指导。这导致了研究基础的大幅扩大，学生的能力更强， 参与导致学生参与者几乎翻了一番，以及职业发展的新举措。在 在INBRE IV中，HiSREP将继续发展新兴研究者，但将扩大 通过一系列新的竞争性拨款机制，与各级生物医学研究科学家建立网络 包括教学博士后奖学金、试点项目、新举措和以团队为基础的合作赠款 发展研究项目计划（DRPP）。HiSREP下的研究将由两个 关键主题，天然产物和分子医学，强调生物医学领域的显着优势， 夏威夷的研究社区。此外，HiSREP将支持重组的生物信息学核心， 在全州范围内集中资源，提供生物信息学教育，帮助研究设计， 技术专长，包括开发新的信息学工具、数据管理和分析。的 生物信息学核心将通过一对一，小组， 讲习班、课程和在线互动，后者通过实时研究社区门户网站进行。的 学生研究计划下的路径生物医学职业将期待拥抱更广泛的， 本科生通过志愿者、实习生、学者和归国人员强调协作小组项目 研究人员的机会，包括与互补的本科研究计划的伙伴关系，而 通过技能培训、实际指导课程， 扩展资源和劳动力发展。此外，PATHway还将积极开发先进的 培训实验室主管，以提高研究的复杂性，以及全州的机会，领先 提高能力。它还将通过纳入以下内容，最终加强本科教育： 研究活动纳入基础科学课程。总的来说，HiSREP将作为促进 研究科学家管道的最终目标是提高生物医学研究的能力 社区作出新的和重要的发现，以改善健康和福祉的夏威夷州。