课题基金 / 基金详情

Skeletal Disorders Training Program

Skeletal Disorders Training Program
骨骼疾病培训计划
批准号:
10615812
负责人:
Roberto Civitelli
金额:
$40.18万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
未结题
起止时间:
2011-05-01 至 2027-04-30

项目摘要

项目成果

Roberto Civitelli的其他基金

相关文献

中文摘要
翻译
华盛顿大学医学院及其附属巴恩斯犹太医院有40年的传统 在肌肉骨骼研究、病人护理、教育和培训方面的卓越成就。2011年,骨骼疾病 培训计划(SDTP)是在Roberto Civitelli博士的领导下建立的,目的是 培训下一代骨骼调查人员,并于2015年续签。此SDTP提供 吴氏肌肉骨骼研究中心的教育和指导基础设施, 医学系(骨和矿物病科)和整形外科,由 NIAMS资助的P30奖项,从而将这一T32和P30的互补目标整合为一个统一的 结构。SDTP提供3个博士后和3个博士后职位,迄今已招收27名实习生(12名 研究生和15名博士后研究员)。在这些人中,5人已晋升为教职员工,5人至 1个获得K99/R00奖励;5个获得F型奖励。 他们总共发表了104篇与该项目直接相关的文章,并获得了无数奖项和 认可。SDTP提供了5个主题领域的研究培训,反映了重点和共同兴趣 参与教师:1)肌肉骨骼生物力学;2)骨骼发育与再生;3) 骨骼和其他系统;4)骨骼免疫学;5)肿瘤-骨骼相互作用。选定的导师 本次SDTP是从吴的9个学术部门和项目中挑选出来的。该计划以4个培训为基础 领域:1)指导研究培训;2)课程设置;3)丰富活动;4)职业 发展。该培训计划建立在生物和生物科学系管理的研究生课程的基础上 生物医学科学和生物医学工程系,并利用翻译研究所 临床科学和其他机构资源。提出的具体创新包括:1)发展 非学术研究培训机会;2)扩大培训的严谨性和可重复性;3)增加 导师教育计划;4)加强以前受训人员的参与,并建立校友网络; 5)在增加城市管理人员参与方案方面作出新的努力;6)更加重视职业发展 训练。这些新的SDTP培训的研究人员将在遗传和分子方面做出未来的发现 骨骼疾病的基础,并最终改善骨质疏松症、炎性骨溶解、 骨关节炎、骨转移和其他骨骼疾病,困扰着很大一部分老年人口。
英文摘要
Washington University School of Medicine and the affiliated Barnes-Jewish Hospital have a 40-year tradition of excellence in musculoskeletal research, patient care, education and training. In 2011, the Skeletal Disorders Training Program (SDTP) was established under the leadership of Dr. Roberto Civitelli, with the purpose of training the next generation of skeletal investigators, and it was renewed in 2015. This SDTP provides the educational and mentoring infrastructure of the WU Musculoskeletal Research Center, a partnership between the Departments of Medicine (Division of Bone and Mineral Diseases) and Orthopaedic Surgery, supported by a NIAMS-funded P30 award, thus integrating the complementary aims of this T32 and the P30 into a unified structure. The SDTP offers 3 pre- and 3 post-doctoral positions and has so far enrolled 27 trainees (12 graduate students and 15 post-doctoral fellows). Of these, 5 have progressed to faculty appointments, 5 to permanent positions in industry; one has been awarded a K99/R00 grant; 5 have received an F-type award. Together, they have published 104 articles directly linked to this program and received numerous awards and recognitions. This SDTP offers research training in 5 thematic areas, reflecting the focus and common interests of the participating faculty: 1) Musculoskeletal Biomechanics; 2) Skeletal Development and Regeneration; 3) The Skeleton and Other Systems; 4) Skeletal Immunology; 5) Tumor-Skeleton Interactions. Mentors selected for this SDTP are drawn from 9 academic Departments and Programs at WU. The program is based on 4 training domains: 1) mentored research training; 2) curriculum coursework; 3) enrichment activities; 4) career development. The training program builds on the graduate programs administered by the Division of Biology and Biomedical Sciences and the Department of Biomedical Engineering and leverages the Institute for Translational and Clinical Sciences and other institutional resources. Specific innovations proposed include,1) development of non-academic research training opportunities; 2) expansion of training in rigor and reproducibility; 3) addition of a mentor education plan; 4) enhanced participation of previous trainees and creation of an Alumni Network; 5) new efforts in increasing participation of URM to the program; 6) increased emphasis on career development training. These new SDTP trained researchers will make the future discoveries in the genetic and molecular bases of skeletal disorders, and eventually improve the treatment of osteoporosis, inflammatory osteolysis, osteoarthritis, bone metastasis, and other skeletal disorders that afflict a large proportion of the elderly population.
期刊论文(4)
专著(0)
科研奖励(0)
会议论文
CORR Insights(®): Does Sclerostin Depletion Stimulate Fracture Healing in a Mouse Model?
CORR Insights(®):硬化蛋白消耗是否会刺激小鼠模型的骨折愈合?
DOI: 10.1007/s11999-016-4697-3
发表时间: 2016
期刊: Clinical orthopaedics and related research
影响因子: 4.2
作者: [Holguin,Nilsson]
通讯作者: Holguin,Nilsson
DOI: 10.1038/s42003-022-03467-w
发表时间: 2022-06-02
期刊: Communications biology
影响因子: 5.9
作者: []
通讯作者:
DOI: 10.1002/jor.24695
发表时间: 2020-11
期刊: Journal of orthopaedic research : official publication of the Orthopaedic Research Society
影响因子: --
作者: [Hill JR, Eekhoff JD, Brophy RH, Lake SP]
通讯作者: Lake SP
N-cadherin in Extraskeletal Osteolineage Cells Modulates Tumor Growth
  • 批准号:
    10442523
  • 项目类别:
  • 资助金额:
    $38.66万
  • 财政年份:
    2020
  • 负责人:
    Roberto Civitelli
  • 依托单位:
N-cadherin in Extraskeletal Osteolineage Cells Modulates Tumor Growth
  • 批准号:
    10204978
  • 项目类别:
  • 资助金额:
    $39.89万
  • 财政年份:
    2020
  • 负责人:
    Roberto Civitelli
  • 依托单位:
N-cadherin in Extraskeletal Osteolineage Cells Modulates Tumor Growth
  • 批准号:
    10654637
  • 项目类别:
  • 资助金额:
    $37.85万
  • 财政年份:
    2020
  • 负责人:
    Roberto Civitelli
  • 依托单位:
Skeletal Disorders Training Program
  • 批准号:
    10410232
  • 项目类别:
  • 资助金额:
    $39.53万
  • 财政年份:
    2011
  • 负责人:
    Roberto Civitelli
  • 依托单位: