Skeletal Disorders Training Program
Skeletal Disorders Training Program
批准号:
10615812
负责人:
Roberto Civitelli
金额:
$40.18万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
未结题
起止时间:
2011-05-01 至 2027-04-30
中文摘要
华盛顿大学医学院和附属的巴恩斯-犹太医院有着40年的传统
卓越的肌肉骨骼研究,病人护理,教育和培训。2011年,Skeleton Disorders
培训计划(SDTP)是在Roberto Civitelli博士的领导下建立的,其目的是
培训下一代骨骼研究人员,并于2015年更新。此SDTP提供
WU肌肉骨骼研究中心的教育和指导基础设施,
内科(骨和矿物疾病科)和矫形外科,由
一个NIAMS资助的P30奖,从而将这个T32和P30的互补目标整合到一个统一的
结构SDTP提供3个博士前和3个博士后职位,迄今已招收27名学员(12
研究生和15名博士后研究员)。其中,5人已晋升为教职员工,5人已晋升为
在工业界的长期职位; 1人获得K99/R 00补助金; 5人获得F类奖。
他们总共发表了104篇与该计划直接相关的文章,并获得了许多奖项,
你的名字。该SDTP在5个主题领域提供研究培训,反映了重点和共同利益
参与教师:1)肌肉骨骼生物力学; 2)骨骼发育和再生; 3)
骨骼和其他系统; 4)骨骼免疫学; 5)肿瘤-骨骼相互作用。选定的导师
这个SDTP是从9个学术部门和计划在WU绘制。该计划基于4个培训
领域:1)指导研究培训; 2)课程; 3)丰富活动; 4)职业生涯
发展该培训计划建立在生物学系管理的研究生课程的基础上,
生物医学科学和生物医学工程系,并利用翻译研究所
临床科学和其他机构资源。具体创新建议包括:(1)发展
非学术研究培训机会; 2)扩大严格性和可重复性培训; 3)增加
(4)加强前学员的参与,建立校友网络;
5)在提高URM对该计划的参与方面做出了新的努力; 6)更加重视职业发展
训练这些新的SDTP培训的研究人员将使未来的发现在遗传和分子
骨骼疾病的基础,并最终改善骨质疏松症,炎性骨质溶解,
骨关节炎、骨转移和其它折磨大部分老年人的骨骼疾病。
英文摘要
Washington University School of Medicine and the affiliated Barnes-Jewish Hospital have a 40-year tradition
of excellence in musculoskeletal research, patient care, education and training. In 2011, the Skeletal Disorders
Training Program (SDTP) was established under the leadership of Dr. Roberto Civitelli, with the purpose of
training the next generation of skeletal investigators, and it was renewed in 2015. This SDTP provides the
educational and mentoring infrastructure of the WU Musculoskeletal Research Center, a partnership between
the Departments of Medicine (Division of Bone and Mineral Diseases) and Orthopaedic Surgery, supported by
a NIAMS-funded P30 award, thus integrating the complementary aims of this T32 and the P30 into a unified
structure. The SDTP offers 3 pre- and 3 post-doctoral positions and has so far enrolled 27 trainees (12
graduate students and 15 post-doctoral fellows). Of these, 5 have progressed to faculty appointments, 5 to
permanent positions in industry; one has been awarded a K99/R00 grant; 5 have received an F-type award.
Together, they have published 104 articles directly linked to this program and received numerous awards and
recognitions. This SDTP offers research training in 5 thematic areas, reflecting the focus and common interests
of the participating faculty: 1) Musculoskeletal Biomechanics; 2) Skeletal Development and Regeneration; 3)
The Skeleton and Other Systems; 4) Skeletal Immunology; 5) Tumor-Skeleton Interactions. Mentors selected
for this SDTP are drawn from 9 academic Departments and Programs at WU. The program is based on 4 training
domains: 1) mentored research training; 2) curriculum coursework; 3) enrichment activities; 4) career
development. The training program builds on the graduate programs administered by the Division of Biology and
Biomedical Sciences and the Department of Biomedical Engineering and leverages the Institute for Translational
and Clinical Sciences and other institutional resources. Specific innovations proposed include,1) development
of non-academic research training opportunities; 2) expansion of training in rigor and reproducibility; 3) addition
of a mentor education plan; 4) enhanced participation of previous trainees and creation of an Alumni Network;
5) new efforts in increasing participation of URM to the program; 6) increased emphasis on career development
training. These new SDTP trained researchers will make the future discoveries in the genetic and molecular
bases of skeletal disorders, and eventually improve the treatment of osteoporosis, inflammatory osteolysis,
osteoarthritis, bone metastasis, and other skeletal disorders that afflict a large proportion of the elderly population.
期刊论文(4)
专著(0)
科研奖励(0)
会议论文
CORR Insights(®): Does Sclerostin Depletion Stimulate Fracture Healing in a Mouse Model?
CORR Insights(®):硬化蛋白消耗是否会刺激小鼠模型的骨折愈合?
DOI:
10.1007/s11999-016-4697-3
发表时间:
2016
期刊:
Clinical orthopaedics and related research
影响因子:
4.2
作者:
[Holguin,Nilsson]
通讯作者:
Holguin,Nilsson
DOI:
10.1002/jor.24695
发表时间:
2020-11
期刊:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
影响因子:
--
作者:
[Hill JR, Eekhoff JD, Brophy RH, Lake SP]
通讯作者:
Lake SP
DOI:
10.1038/s42003-022-03467-w
发表时间:
2022-06-02
期刊:
Communications biology
影响因子:
5.9
作者:
[]
通讯作者:
N-cadherin in Extraskeletal Osteolineage Cells Modulates Tumor Growth
-
批准号:10442523
-
项目类别:
-
资助金额:$38.66万
-
财政年份:2020
-
负责人:Roberto Civitelli
-
依托单位:
N-cadherin in Extraskeletal Osteolineage Cells Modulates Tumor Growth
-
批准号:10204978
-
项目类别:
-
资助金额:$39.89万
-
财政年份:2020
-
负责人:Roberto Civitelli
-
依托单位:
N-cadherin in Extraskeletal Osteolineage Cells Modulates Tumor Growth
-
批准号:10654637
-
项目类别:
-
资助金额:$37.85万
-
财政年份:2020
-
负责人:Roberto Civitelli
-
依托单位:
Skeletal Disorders Training Program
-
批准号:10410232
-
项目类别:
-
资助金额:$39.53万
-
财政年份:2011
-
负责人:Roberto Civitelli
-
依托单位:
Skeletal Disorders Training Program
-
批准号:9914220
-
项目类别:
-
资助金额:$36.59万
-
财政年份:2011
-
负责人:Roberto Civitelli
-
依托单位:
Metabolic Skeletal Disorders Training Program Grant
-
批准号:8077841
-
项目类别:
-
资助金额:$31.54万
-
财政年份:2011
-
负责人:Roberto Civitelli
-
依托单位:
Skeletal Disorders Training Program
-
批准号:9262153
-
项目类别:
-
资助金额:$27.13万
-
财政年份:2011
-
负责人:Roberto Civitelli
-
依托单位:
Metabolic Skeletal Disorders Training Program Grant
-
批准号:8465097
-
项目类别:
-
资助金额:$20.42万
-
财政年份:2011
-
负责人:Roberto Civitelli
-
依托单位:
Metabolic Skeletal Disorders Training Program Grant
-
批准号:8240979
-
项目类别:
-
资助金额:$30.18万
-
财政年份:2011
-
负责人:Roberto Civitelli
-
依托单位:
Metabolic Skeletal Disorders Training Program Grant
-
批准号:8660654
-
项目类别:
-
资助金额:$28.75万
-
财政年份:2011
-
负责人:Roberto Civitelli
-
依托单位:
Smad4/B-Catenin Signaling Cross-Talk for Osteoblastogenesis
-
批准号:8434952
-
项目类别:
-
资助金额:$31.19万
-
财政年份:2010
-
负责人:Roberto Civitelli
-
依托单位:
Smad4/B-Catenin Signaling Cross-Talk for Osteoblastogenesis
-
批准号:8608999
-
项目类别:
-
资助金额:$32.18万
-
财政年份:2010
-
负责人:Roberto Civitelli
-
依托单位:
Smad4/B-Catenin Signaling Cross-Talk for Osteoblastogenesis
-
批准号:8213516
-
项目类别:
-
资助金额:$32.83万
-
财政年份:2010
-
负责人:Roberto Civitelli
-
依托单位:
Smad4/B-Catenin Signaling Cross-Talk for Osteoblastogenesis
-
批准号:7789919
-
项目类别:
-
资助金额:$34.2万
-
财政年份:2010
-
负责人:Roberto Civitelli
-
依托单位:
Smad4/B-Catenin Signaling Cross-Talk for Osteoblastogenesis
-
批准号:8018090
-
项目类别:
-
资助金额:$32.83万
-
财政年份:2010
-
负责人:Roberto Civitelli
-
依托单位:
Cadherin Mediated Cell-Cell Interactions in the Bone Microenvironment
-
批准号:7890453
-
项目类别:
-
资助金额:$33.86万
-
财政年份:2009
-
负责人:Roberto Civitelli
-
依托单位:
Cadherin Mediated Cell-Cell Interactions in the Bone Microenvironment
-
批准号:8092787
-
项目类别:
-
资助金额:$32.5万
-
财政年份:2009
-
负责人:Roberto Civitelli
-
依托单位:
Cadherin Mediated Cell-Cell Interactions in the Bone Microenvironment
-
批准号:8291152
-
项目类别:
-
资助金额:$32.5万
-
财政年份:2009
-
负责人:Roberto Civitelli
-
依托单位:
Cadherin Mediated Cell-Cell Interactions in the Bone Microenvironment
-
批准号:8499014
-
项目类别:
-
资助金额:$30.88万
-
财政年份:2009
-
负责人:Roberto Civitelli
-
依托单位:
Cadherin Mediated Cell-Cell Interactions in the Bone Microenvironment
-
批准号:7729533
-
项目类别:
-
资助金额:$34.2万
-
财政年份:2009
-
负责人:Roberto Civitelli
-
依托单位: