Developing and testing an intervention to enhance recovery capital amid opioid use disorder pharmacotherapy: A pilot randomized trial of assertive linkage to recovery community centers
Developing and testing an intervention to enhance recovery capital amid opioid use disorder pharmacotherapy: A pilot randomized trial of assertive linkage to recovery community centers
批准号:
10590626
负责人:
Lauren A Hoffman
金额:
$18.5万
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
未结题
起止时间:
2022-03-15 至 2027-02-28
关键词:
AddressAdherenceAdoptedAftercareAmbulatory CareAphorismsAssertivenessAwardBuprenorphineCapitalChronicClinicClinicalClinical TreatmentCommunitiesCoping SkillsDataDevelopmentDisease remissionEnsureEvaluationExhibitsFeasibility StudiesFeedbackFoundationsFutureGoalsGuidelinesHappinessHousingImpairmentIndividualInterventionIntervention StudiesInterviewLinkMaintenanceManualsMeasuresMentorsMethodsNational Institute of Drug AbuseOutcomeOverdosePathway interactionsPatientsPersonal SatisfactionPersonsPharmaceutical PreparationsPharmacotherapyProceduresProtocols documentationPublic HealthPublishingQualitative MethodsRandomizedRandomized, Controlled TrialsRecoveryRecovery SupportResearchResourcesRiskServicesStressSubstance Use DisorderTelephoneTestingTrainingVisitWorkbiobehaviorbuprenorphine treatmentclinical practiceclinically relevantcommunity centerdesignexperiencefollow-uphealth determinantsimprovedinsightmeetingsmembernovelopioid epidemicopioid misuseopioid use disorderoptimismpatient retentionpeerpeer supportprogramsprotective effectprovider interventionpsychosocialrandomized trialrecovery servicesrecruitrelapse riskretention ratesafety netsatisfactionsecondary outcomesustained recoverytherapy developmenttreatment programvolunteer
中文摘要
点击翻译按钮获取中文摘要
英文摘要
(K.220) 7. Project Summary/Abstract
Opioid use disorder (OUD) is associated with disproportionate deficits in the psychosocial determinants of health,
with individuals exhibiting recovery capital (i.e. recovery resources) that is one standard deviation below that of
other substance use disorders (SUDs) in the first year of recovery. OUD medications (MOUDs) are first-line
treatments (Txs) that facilitate recovery by addressing the biophysiological disturbances caused by chronic
opioid misuse. Yet, high rates of MOUD discontinuation and associated risks are ongoing concerns and, even
when patients (Ps) are retained in Tx, psychosocial deficits often persist, increasing biobehavioral stress and
hindering Tx/recovery. Thus, without a foundation of resources for recovery support/maintenance, current and
former MOUD Ps are at ongoing risk for psychosocial impairment, which hinders recovery. The provision of
recovery support services (RSS) offers one way to address extra-Tx needs and enhance recovery capital to
ensure a safety net of resources and healthy coping skills to support MOUD Ps during and after Tx. Recovery
Community Centers (RCCs) are a free, newly emerging, and rapidly growing tier of RSS that serve as ‘one-stop-
shops’ for recovery capital, offering an array of services catered to the SUD community. RCCs seem to be
especially well suited for MOUD Ps, as they operate under the maxim “many pathways [to recovery], all should
be celebrated” (including MOUD), and the majority of RCC attendees have OUD and hold positive attitudes
toward MOUD. Though early evidence suggests that RCCs can aid SUD recovery, its potential benefit to MOUD
Ps has yet to be directly studied. Also, few MOUD Ps know of or use RCCs, and clinical linkage to them is
uncommon. Thus, this 5-year project seek to advance our understanding of the clinical and public health utility
of RCCs and help bridge the gap between clinical Tx and community-based RSS. As a first step in this work, we
will develop and test a new intervention for peer-facilitated assertive linkage of MOUD Ps to RCCs (RCCL),
relative to a matched control condition (CC). This study aims to: (1) develop, manualize, and refine RCCL/CC
protocols via stakeholder feedback; (2) determine feasibility, acceptability, and preliminary efficacy (RCC
attendance, service use, recovery capital) of RCCL vs. CC, via a pilot randomized controlled trial (RCT); (3) Gain
in-depth insight to RCCL via qualitative interviews. This study will be the first to test RCCL for MOUD Ps,
providing a foundation for larger-scale RCTs, with the potential to ultimately change clinical practice paradigms
to address Ps’ extra-Tx needs and inform our ability to expand RCCL provision nationally. The aims support
advanced training in: psychosocial determinants of health; RSS; intervention development/testing (via RCT);
qualitative methods; ongoing OUD training, with a new focus on intervention research. Training will be fulfilled
with expert guidance from Drs. John Kelly, Roger Weiss, Joanne Neale, David Best, Christine Timko, and Corrie
Vilsaint. The training and experience provided by this award will serve as a critical foundation from which to build
a an important and clinically relevant program of independent research.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Opioid use disorder, cognition, and recovery: An investigation of neuropsychological change and associated recovery outcomes in buprenorphine and methadone treated patients [SUPPLEMENT]
-
批准号:10405308
-
项目类别:
-
资助金额:$1.56万
-
财政年份:2022
-
负责人:Lauren A Hoffman
-
依托单位:
Developing and testing an intervention to enhance recovery capital amid opioid use disorder pharmacotherapy: A pilot randomized trial of assertive linkage to recovery community centers
-
批准号:10427936
-
项目类别:
-
资助金额:$18.52万
-
财政年份:2022
-
负责人:Lauren A Hoffman
-
依托单位:
Opioid use disorder, cognition, and recovery: An investigation of neuropsychological change and associated recovery outcomes in buprenorphine and methadone treated patients
-
批准号:10092146
-
项目类别:
-
资助金额:$7.31万
-
财政年份:2019
-
负责人:Lauren A Hoffman
-
依托单位:
海外基金