Physician-Scientist Training in Emerging Infectious Diseases

项目摘要/摘要 德克萨斯大学医学院分校(UTMB)的这项新的机构培训补助金(T32)申请将 为新发传染病的内科科学家提供多学科和跨专业的研究培训 疾病(EID)。目前面临埃博拉疫情暴发和流行的风险和可能性凸显 迫切需要培养具有临床医学跨学科技能的内科科学家， 流行病学、实地调查、实验室科学和生物控制。该计划利用了世界-- 一流的教师专业知识、长期的机构承诺和独特的研究资源。它包括 有针对性地在地方、区域和国家各级招聘候选人。候选人将是符合以下条件的医生 完成或已经完成ACGME认证的居留或奖学金。每年将有一名实习生进入 在5年制课程期间完成2-3年的培训。培训包括1)中的指导和指导 团队科学；2)研究设计、流行病学方法和生物统计学(临床科学硕士)； EID和暴发调查；4)临床和研究生物控制/生物安全；5)负责任地进行 研究；6)现场流行病学；7)科学写作。每个学员将通过以下方式应用其培训 在通过小说接受密集的科学和职业指导的同时进行翻译研究 团队科学框架称为个性化多学科、跨专业导师团队(IMIMT)。 每个iMIMT将包括受训者、一名初级和二级导师(一名博士科学家和一名医学博士科学家)，以及 2到3名同行或专业知识导师。IMIMTS将接受定期的团队科学培训和 教练。助学金编写的指导最终将在#年提交一份NIH职业发展申请 最后一年的训练。定期但有限的临床责任将使学员能够保持临床技能 并学习如何管理双重的临床研究生涯。我们的29名项目教员拥有富有成效的翻译 EID中的研究计划和成功指导的记录。他们通过合作来补充 来自秘鲁、哥伦比亚、墨西哥、多米尼加共和国和巴西的调查人员。额外的计划支持教师 拥有方案/业务支持方面的专门知识。学员的个性化发展 计划包括明确定义的培训活动、预期能力、成功指标和 完成了。联合计划主任和3名副计划主任将在指导下领导该计划 委员会治理。小组委员会将监督学员的招募和遴选、指导和 科学进步。一个外部咨询委员会将每年对该计划的进展情况进行评估。在… 完成后，我们的学员将对EID有很强的跨学科理解，并将以研究为基础 方法和疫情调查，将拥有协作解决问题的工具和关键技能 手稿和赠款写作。所有这些都将有助于他们向独立的内科科学家过渡。

PROJECT SUMMARY/ABSTRACT This new Institutional Training Grant (T32) application from the University of Texas Medical Branch (UTMB) will provide multidisciplinary and interprofessional research training for physician-scientists in emerging infectious diseases (EIDs). The ongoing risk and likelihood of facing outbreaks and epidemics caused by EIDs highlights a critical need for developing physician-scientists with trans-disciplinary skills in clinical medicine, epidemiology, field investigation, laboratory science, and biocontainment. The program capitalizes on world- class faculty expertise, longstanding institutional commitments, and unique research resources. It includes targeted recruitment of candidates at local, regional and national levels. Candidates will be physicians who are completing or have completed, an ACGME-certified residency or fellowship. One trainee per year will enter and complete 2-3 years of training during the 5-year program. Training includes instruction and mentorship in 1) team science; 2) research design, epidemiological methods, and biostatistics (MSc in Clinical Science); 3) EIDs and outbreak investigation; 4) clinical and research biocontainment/biosafety; 5) responsible conduct of research; 6) field epidemiology; and 7) scientific writing. Each of the trainees will apply their training by conducting translational research while receiving intensive scientific and career mentorship through a novel Team Science framework called individualized Multidisciplinary, Interprofessional Mentorship Team (iMIMT). Each iMIMT will include the trainee, a primary and secondary mentor (a PhD scientist and a MD scientist), and 2 or 3 peer or specialized knowledge mentors. iMIMTs will receive regular Team Science training and coaching. Instruction in grant writing will culminate in submission of an NIH career development application in the last year of training. Regular, but limited clinical responsibility will enable trainees to maintain clinical skills and learn how to manage a dual clinical-research career. Our 29 program faculty have productive translational research programs in EIDs and a record of successful mentoring. They are complemented by collaborating investigators from Peru, Colombia, Mexico, Dominican Republic, and Brazil. Additional program support faculty have specialized expertise for programmatic/operational support. The trainees' individualized development plan includes well-defined training activities, expected competencies, indicators of success, and a timeline for completion. Co-Program Directors and 3 Associate Program Directors will lead the program under Steering Committee governance. Sub-committees will oversee trainees' recruitment and selection, mentorship, and scientific progress. An External Advisory Committee will evaluate the program's progress annually. At completion, our trainees will have strong trans-disciplinary understanding of EIDs, will be grounded in research methods and outbreak investigation, will have tools for collaborative problem-solving, and critical skills in manuscript and grant writing. All of these will facilitate their transition to an independent physician-scientist.