Novel Nanotechnology for the Delivery of Amyloid and Tau aggregation Targeting siRNA for a potential Alzheimer’s Disease Therapy
Novel Nanotechnology for the Delivery of Amyloid and Tau aggregation Targeting siRNA for a potential Alzheimer’s Disease Therapy
用于输送淀粉样蛋白和 Tau 聚集的新型纳米技术 靶向 siRNA 的潜在阿尔茨海默病治疗方法
批准号：
nhmrc : GNT1166024
负责人：
金额：
$47.26万
依托单位：
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2019
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2019-01-01 至 --
中文摘要
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英文摘要
A key challenge for treating neurodegenerative diseases is delivery of drugs across the blood–brain barrier (BBB). This project will develop advanced BBB “nanoshuttles” based on the role of the GLUT family of transporters to facilitate BBB delivery and specific neuronal uptake to transport nanotherapeutics into brain and target the key protein towards future AD clinical therapy.
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