权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Reducing Lung Cancer Risk among Appalachian Women Using Community‐Engaged Intervention Research

利用社区参与干预研究降低阿巴拉契亚女性患肺癌的风险

基本信息

批准号：
10579417
负责人：
Jessica Ruth Thompson
金额：
$ 10.43万
依托单位：
UNIVERSITY OF KENTUCKY
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-02-01 至 2025-01-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10579417
关键词：
18 year old Active Learning Address Affect Appalachian Region Area Attitude Awareness Behavior Behavior Therapy Behavioral Cancer Center Cancer Etiology Cancer Intervention Cessation of life Chronic Disease Chronic stress Clinical Sciences Collaborations Communities Coping Behavior Country County Development Development Plans Diagnosis Economically Deprived Population Effectiveness of Interventions Enrollment Environment Environmental Exposure Environmental Risk Factor Equity Evidence based intervention Farm Funding Future Gender Goals Health Health Technology High Risk Woman Incidence Individual Insurance Intervention Intervention Studies Intervention Trial Kentucky Knowledge Literature Malignant Neoplasms Malignant neoplasm of lung Mentors Mentorship Methods Mining Modeling NCI-Designated Cancer Center Needs Assessment Participant Passive Smoking Perception Persons Phase Population Postdoctoral Fellow Poverty Preventive Preventive screening Preventive service Process Protocols documentation Psychosocial Factor Quality of life Radon Randomized, Controlled Trials Research Research Methodology Research Personnel Risk Risk Factors Risk Reduction Rural Rural Appalachia Sample Size Science Scientist Self Efficacy Series Smoking Source Specificity Surveys System Targeted Research Training Translational Research Trust United States National Institutes of Health Universities Water Woman cancer health disparity cancer risk care giving burden career development clinical center community center community-level factor disorder prevention experience falls geographic disparity health care availability health disparity health disparity populations health economics health equity human centered design implementation cost implementation science improved intervention mapping intervention refinement lung cancer prevention men model building mortality non-smoker pilot test primary care provider public policy on tobacco satisfaction service providers sex skills social socioeconomic disadvantage socioeconomic disparity therapy development training opportunity

项目摘要

PROJECT SUMMARY Appalachian women are at high risk for lung cancer. Lung cancer is the leading cause of cancer-related death for women in the US, including the Appalachian region. Although lung cancer rates have declined steadily among men since the 1990s, such decreases have not been seen among women, including alarming mortality rates in Central Appalachia. Interventions to reduce lung cancer risk among Appalachian women need to consider social and environmental contexts. Research: This project, titled Reducing Lung Cancer Risk among Appalachian Women Using Community-Engaged Intervention Research, relies on community perspectives to guide the selection, adaptation, and pilot testing of a culturally-targeted intervention to reduce lung cancer risk among Appalachian women. We will employ the NIH model for creating behavioral intervention trials to inform the refinement of an intervention through direct community input (Phase 1a; Aim 1; K99) and to pilot test the selected and adapted intervention protocol using a 2-armed randomized controlled trial (Phase 1b; Aim 2; R00). In the pilot with Central Appalachian KY women, we will demonstrate the feasibility of the adapted intervention protocol, including demand, acceptability, and implementation. The selected intervention will seek to increase knowledge, self-efficacy, and targeted behaviors among Appalachian women thereby reducing their future lung cancer risk and, ultimately, lung cancer disparities among women in the Appalachian region. Candidate: Dr. Jessica Thompson is a postdoctoral scholar in an NCI-designated cancer center at the University of Kentucky (UK) with extensive previous training in community-engaged mixed methods research and chronic disease prevention among Appalachian women. Three training goals will enhance her trajectory toward becoming an independent investigator, including developing expertise in: 1) the use of participatory systems science and community- engaged approaches to select and adapt an intervention; 2) lung cancer prevention and risk reduction interventions; and 3) intervention development and implementation science. Mentors/Environment: Dr. Thompson’s career development plan includes substantial mentorship, didactic training, and experiential learning at the UK Markey Cancer Center (MCC) with additional support from the UK Center for Health Equity Transformation (CHET) and the UK Center for Clinical and Translational Science (CCTS). She will receive direct mentorship from MCC Community Impact Office director Dr. Pamela Hull (Primary Mentor) and CHET director Dr. Nancy Schoenberg (Co-Primary Mentor) with additional mentorship from Dr. Ellen Hahn (Mentor) in lung cancer prevention and risk reduction, Dr. Teresa Waters (Mentor) in assessments of intervention effectiveness and health economics, and Dr. Jessica Burke (Mentor; University of Pittsburgh) in systems science and participatory methods. Overall, the objectives of this K99/R00 application will advance lung cancer intervention research for Appalachian women by providing evidence for a future R01 submission and support Dr. Thompson’s training as an independent scientist in implementing interventions to improve the health of Appalachian women.

项目总结