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Novel Therapies to Enhance Immunity to Cancer

Novel Therapies to Enhance Immunity to Cancer
增强癌症免疫力的新疗法
批准号：
nhmrc : GNT1122311
负责人：
Dr Conor Kearney
金额：
$31.88万
依托单位：
依托单位国家：
澳大利亚
项目类别：
Early Career Fellowships
财政年份：
2017
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2017-01-01 至 --
来源：
https://researchdata.edu.au/novel-therapies-enhance-immunity-cancer/1347264
关键词：
NovelTherapiesEnhanceImmunityCancer

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中文摘要
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英文摘要
This project will investigate a new class of targeted drugs called Smac-mimetics. These drugs are proving extremely effective in promoting the death of cancer cells. Here, we aim to better understand how Smac-mimetics work as a cancer therapeutic and how they promote immune responses to cancer. This will enable us to identify combination therapies that elicit both death of the cancer cell and stimulate the immune system to promote tumour clearance.
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会议论文
Exploring the Inflammatory Signature of the anti-cancer Smac-mimetic, Birinapant, and the contribution of this signature to Birinapant anti-Tumour activity
  • 批准号：
    nhmrc : GNT1101244
  • 项目类别：
    Project Grants
  • 资助金额：
    $19.23万
  • 财政年份：
    2016
  • 负责人：
    Dr Conor Kearney
  • 依托单位：
国内基金
海外基金
Autoimmune diseases therapies: variations on the microbiome in rheumatoid arthritis
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data