Cancer Prevention and Control Program

癌症预防和控制程序：摘要 癌症预防和控制(CPC)计划的总体目标是了解和解决高 影响俄克拉荷马州(SCC集水区)癌症和癌症相关差异，重点关注差异 在该州的美国印第安人(AI)、黑人/非裔美国人(Black/AA)、农村和其他社会经济领域 弱势群体。该计划的具体目标集中在：1)确定遗传、环境、 导致俄克拉荷马州癌症高发病率和差异的行为和社会风险因素；2) 制定、评估和实施干预措施，以降低癌症发病率和死亡率；以及3) 通过加强护理机会、接生和存活率来改善癌症预后。与……密切互动 社区外联和参与(COE)副主任(Mark Doescher，MD)和核心帮助 促进以流域为重点的研究和社区伙伴关系。CPC计划的目标已经演变 自上届CCSG以来，在中心和计划规划的推动下，新的战略机遇，成熟的 方案活动，以及应对集水区新出现的癌症问题。修订后的计划 AIMS现在反映了更广泛的范围以及更大的整合和协同作用，以应对 集水区。 CPC项目有43名成员(25名正式成员和18名助理成员)，代表18个学术部门和一个 一系列跨学科的专业知识，包括：癌症健康差异、社区参与性 研究；烟草预防和戒烟的新干预措施；新兴烟草产品；基础 成瘾机制；护理协调、提供和生存；以及治疗的基本机制-- 相关副作用。在过去五年中，CPC计划在以下各项指标方面取得了重大进展 程序性活动。CPC计划的净资产净值大幅增加(264万美元365万美元) 和自上次CCSG以来的同行评审研究资金总额(558万美元727万美元)，反映了战略 计划、有针对性的招聘、发展资金的分配以及SCC的增值支持。钥匙 自上次CCSG以来，出版指标也大幅增加，包括：方案内(36% 40%)、计划间(6%29%)、多机构(82%)和高影响力(1%8%) [影响因子≥10]。方案间合作出版物直接增加了近五倍 解决了先前CCSG中的一项计划批评。CPC项目提供了大量的培训和指导 面向本科生和研究生、博士后研究员和初级教员的课程。CPC项目由以下人员领导 Paul Spicer博士、Darla Kendzor博士和C.V.Rao博士，他们拥有多样化和互补性 跨学科的专业知识，以推进项目目标。

CANCER PREVENTION AND CONTROL PROGRAM: ABSTRACT The overall goal of the Cancer Prevention and Control (CPC) program is to understand and address high- impact cancers and cancer-related disparities in Oklahoma (SCC catchment area), with a focus on disparities in the state's American Indian (AI), Black / African American (Black/AA), rural, and other socioeconomically disadvantaged populations. Specific aims of the program focus on: 1) identifying genetic, environmental, behavioral, and social risk factors that contribute to high cancer incidence and disparities in Oklahoma; 2) developing, evaluating and implementing interventions to reduce to cancer incidence and mortality; and 3) improving cancer outcomes through enhancing care access, delivery and survivorship. Close interactions with the Community Outreach and Engagement (COE) Associate Director (Mark Doescher, MD) and Core help facilitate catchment area-focused research and community partnerships. CPC program aims have evolved since the last CCSG, driven by center and program planning, new strategic opportunities, maturation of program activities, and in response to emerging cancer problems in the catchment area. Revised program aims now reflect a broader scope as well as greater integration and synergy of activity to address cancer in the catchment area. The CPC program has 43 members (25 full and 18 associate), representing 18 academic departments and a range of transdisciplinary expertise, including: cancer health disparities, community-based participatory research; novel interventions for tobacco prevention and cessation; emerging tobacco products; basic mechanisms of addiction; care coordination, delivery and survivorship; and basic mechanisms of treatment- related side effects. The CPC program made significant progress during past five years on all metrics for programmatic activities. The CPC program has experienced significant increases in NCI ($2.64M  $3.65M) and total peer-reviewed research funding ($5.58M  $7.27M) since the last CCSG, reflecting strategic planning, targeted recruitment, allocation of developmental funds, and value-added support from the SCC. Key publication metrics have also significantly increased since the last CCSG, including: intra-programmatic (36%  40%), inter-programmatic (6%  29%), multi-institutional (64%  82%), and high impact (1%  8%) [impact factor ≥10]. The nearly five-fold increase in inter-programmatic collaborative publications directly addresses a program critique in the prior CCSG. The CPC program hosts numerous training and mentorship programs for under- and graduate students, postdoctoral fellows and junior faculty. The CPC program is led by Paul Spicer, PhD, Darla Kendzor, PhD, and C.V. Rao, PhD, who have diverse and complementary transdisciplinary expertise to advance program aims.