Cancer Prevention and Control Program

癌症预防和控制计划

• 批准号: 10627032
• 负责人: Darla Elizabeth Kendzor
• 金额: $ 7.83万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627032
• 关键词: Address; African American; American Indians; Area; Basic Science; Behavioral; Behavioral Sciences; Black race; Cancer Center; Cancer Center Support Grant; Cancer Control; Catchment Area; Chemopreventive Agent; Clinical Sciences; Collaborations; Community Outreach; Complex; Continuance of life; Continuity of Patient Care; Critiques; DNA Damage; Development; Disease; Disparity; Doctor of Philosophy; Economically Deprived Population; Emerging Tobacco Products; Evaluation; Faculty; Financial Hardship; Funding; Future; Genetic; Genomics; Goals; Growth; Health Services Accessibility; Health behavior; Incentives; Incidence; Inflammatory; Institution; Intervention; Intervention Trial; Laboratories; Life Style Modification; Malignant Neoplasms; Menthol; Mentors; Mentorship; Monitor; NCI-Designated Cancer Center; Not Hispanic or Latino; Oklahoma; Outcome; Pain management; Pathway interactions; Peer Review; Play; Population; Population Sciences; Positioning Attribute; Postdoctoral Fellow; Poverty; Publications; Quality of life; Race; Research; Research Peer Review; Research Personnel; Resource Sharing; Risk; Risk Factors; Role; Rural; Strategic Planning; Symptoms; Tobacco Use Cessation; Tobacco use; Training; Treatment Side Effects; Underserved Population; Work; abuse liability; addiction; cancer care; cancer health disparity; cancer prevention; cancer risk; care coordination; chemobrain; community based participatory research; community engagement; community partnership; epidemiologic discoveries; experience; graduate student; improved; innovation; interdisciplinary collaboration; lung cancer screening; mHealth; member; metabolomics; mortality; novel; prevent; programs; racial population; recruit; response; rural area; rural cancer care; rural poverty; rural residence; screening; social; socioeconomic disadvantage; survivorship; synergism; tobacco prevention; tribal Nation; tumor progression; uptake

CANCER PREVENTION AND CONTROL PROGRAM: ABSTRACT The overall goal of the Cancer Prevention and Control (CPC) program is to understand and address high- impact cancers and cancer-related disparities in Oklahoma (SCC catchment area), with a focus on disparities in the state's American Indian (AI), Black / African American (Black/AA), rural, and other socioeconomically disadvantaged populations. Specific aims of the program focus on: 1) identifying genetic, environmental, behavioral, and social risk factors that contribute to high cancer incidence and disparities in Oklahoma; 2) developing, evaluating and implementing interventions to reduce to cancer incidence and mortality; and 3) improving cancer outcomes through enhancing care access, delivery and survivorship. Close interactions with the Community Outreach and Engagement (COE) Associate Director (Mark Doescher, MD) and Core help facilitate catchment area-focused research and community partnerships. CPC program aims have evolved since the last CCSG, driven by center and program planning, new strategic opportunities, maturation of program activities, and in response to emerging cancer problems in the catchment area. Revised program aims now reflect a broader scope as well as greater integration and synergy of activity to address cancer in the catchment area. The CPC program has 43 members (25 full and 18 associate), representing 18 academic departments and a range of transdisciplinary expertise, including: cancer health disparities, community-based participatory research; novel interventions for tobacco prevention and cessation; emerging tobacco products; basic mechanisms of addiction; care coordination, delivery and survivorship; and basic mechanisms of treatment- related side effects. The CPC program made significant progress during past five years on all metrics for programmatic activities. The CPC program has experienced significant increases in NCI ($2.64M  $3.65M) and total peer-reviewed research funding ($5.58M  $7.27M) since the last CCSG, reflecting strategic planning, targeted recruitment, allocation of developmental funds, and value-added support from the SCC. Key publication metrics have also significantly increased since the last CCSG, including: intra-programmatic (36%  40%), inter-programmatic (6%  29%), multi-institutional (64%  82%), and high impact (1%  8%) [impact factor ≥10]. The nearly five-fold increase in inter-programmatic collaborative publications directly addresses a program critique in the prior CCSG. The CPC program hosts numerous training and mentorship programs for under- and graduate students, postdoctoral fellows and junior faculty. The CPC program is led by Paul Spicer, PhD, Darla Kendzor, PhD, and C.V. Rao, PhD, who have diverse and complementary transdisciplinary expertise to advance program aims.

癌症预防和控制计划：摘要 癌症预防和控制（CPC）计划的总体目标是了解和解决高 俄克拉荷马州（SCC集水区）​​的影响癌症和与癌症相关的差异，重点是差异 在该州的美洲印第安人（AI），黑人 /非裔美国人（黑人 / AA），粗糙和其他社会经济上 弱势群体。该计划的具体目的重点是：1）确定遗传，环境， 行为和社会风险因素导致俄克拉荷马州的癌症发病率和差异高； 2） 开发，评估和实施干预措施，以降低癌症的发病率和死亡率； 3） 通过增强护理访问，分娩和生存来改善癌症结果。与 社区宣传与参与（COE）副主任（Mark Docher，MD）和核心帮助 促进以集水区为重点的研究和社区伙伴关系。 CPC计划的目标已经发展 自上次CCSG以来，由中心和计划计划，新的战略机会，成熟 计划活动，以及回应集水区的癌症问题。修订程序 目的现在反映了更广泛的范围以及活动的更大整合和协同作用，以解决癌症 集水区。 CPC计划有43名成员（25名完整和18个同事），代表18个学术部门和一个 跨学科专业知识范围，包括：癌症健康差异，基于社区的参与 研究;预防烟草的新干预措施；新兴的烟草产品；基本的 成瘾的机制；护理协调，分娩和生存；和治疗的基本机制 - 相关的副作用。 CPC计划在过去五年中在所有指标上取得了重大进展 编程活动。 CPC计划的NCI大幅增加（264万美元365万美元） 自上次CCSG以来，经过同行评审的研究资金（558万美元727万美元），反映了策略 计划，有针对性的招聘，发展基金的分配以及SCC的增值支持。钥匙 自上次CCSG以来，出版指标也已大大增加，包括：概括（36％） 40％），程序间（6％29％），多机构（64％82％）和高影响力（1％8％） [影响因子≥10]。直接的程序间协作出版物的近五倍 解决了先前CCSG中至关重要的程序。 CPC计划主持众多培训和精神训练 针对未成年人和研究生，博士后研究员和初级教师的课程。 CPC程序由 Paul Spicer博士，Darla Kendzor博士和C.V. Rao，PhD，拥有潜水员和完整性的 跨学科的专业知识促进计划的目标。