Training in Mechanisms and Clinical Presentation of Pain

疼痛机制和临床表现培训

• 批准号: 10627083
• 负责人: MICHAEL S GOLD
• 金额: $ 28.75万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627083
• 关键词: Clinical; Pain; Training

The overarching goal of this training program is to train the next generation of pain researchers. We will continue to train both pre- (two per year) and post-doctoral (two per year) fellows in the fundamental principles of pain, as nociceptive signals arise and are modulated throughout the body and ultimately integrated in the brain to produce the sensory and emotional experience. We will continue to build on the training program developed through the first two funding periods of this grant around a combination of more formal coursework and less formal training experiences designed to provide not only a solid background in pain mechanisms and management, and a greater appreciation of the burden of pain, but in a variety of skills critical for career development including the use of cutting edge and rigorous and statistically sound methodology, literacy in quantitative approaches to pain research, networking, and oral and written communication. We are committed to an integrated approach to the study of pain which is based on our belief that major breakthroughs in this field can only be achieved through multidisciplinary approaches. This is most clearly manifest in practice through interactions between [1] laboratories (horizontal integration) and [2] researchers and clinicians (vertical integration). Accordingly, horizontal and vertical integration are essential components of this training program, which consists of three core elements: 1) Research - Multidisciplinary research projects are not only encouraged, but expected, as is exposure to clinical management of pain/pain-related problems. Horizontal and vertical integration will be achieved both through the choice of project, shaped by a primary mentor with input from the executive committee, and through the formation of multidisciplinary mentoring committees which will include at least one clinical faculty member among a three to four-member committee. 2) Theory - Trainees participate in four required for-credit courses: Mechanisms and Clinical Presentation of Pain, Pain Journal Club, bi-weekly Current Research on Pain presentations, and Pain Models – Rationale, Testing and Interpretation, as well as the monthly Pain Seminar Series, where trainees interact with prominent pain researchers. These courses serve as a primary venue to address issues of scientific rigor, proper use of statistics in experimental design and analysis, quantitative literacy, as well as reinforce issues associated with the responsible conduct of research. 3) Practice - Trainees will be exposed to the assessment, diagnosis and treatment of chronic pain patients through three primary venues: 1) the Mechanisms of Clinical Presentation of Pain course includes a series of lectures directed at assessment diagnosis and treatment of specific subpopulations/aspects of pain patients (visceral, headache, geriatric, etc); 2) One-on-one interactions with a clinician as a member of the training committee, that is often associated with opportunities for trainees to shadow pain physicians as they interview, diagnose and manage pain patients; and 3) Participation in activities organized by the Challenges in Managing and Preventing Pain (CHAMPP) Clinical Pain Research Center that involves exposure to clinical pain research, pain clinicians, and pain patients.

该培训计划的总体目标是培训下一代疼痛研究人员。我们将 继续对博士前研究员（每年两名）和博士后研究员（每年两名）进行基本原则培训 当伤害性信号出现并在整个身体中进行调节并最终整合到身体中时，疼痛就会消失 大脑产生感官和情感体验。我们将继续加强培训计划 通过该赠款的前两个资助期围绕更正式的课程作业进行开发 以及不太正式的培训经验，旨在不仅提供疼痛机制的坚实背景， 管理，并更加认识到痛苦的负担，但在对职业生涯至关重要的各种技能中 发展，包括使用尖端、严格和统计上合理的方法、扫盲 疼痛研究、网络以及口头和书面交流的定量方法。我们承诺 一种研究疼痛的综合方法，这是基于我们的信念，即在这方面取得重大突破 领域只能通过多学科方法来实现。这在实践中表现得最为明显 通过[1]实验室（横向整合）和[2]研究人员和临床医生（纵向整合）之间的互动 一体化）。因此，横向和纵向整合是该培训计划的重要组成部分， 它由三个核心要素组成： 1）研究——多学科研究项目不仅是 鼓励但预期，就像接触疼痛/疼痛相关问题的临床管理一样。水平的 垂直整合将通过项目选择来实现，该项目由主要导师塑造 执行委员会的投入，并通过成立多学科指导委员会， 由三到四人组成的委员会中至少包括一名临床教职人员。 2) 理论-学员 参加四门必修学分课程：疼痛的机制和临床表现、疼痛杂志 俱乐部，每两周一次的当前疼痛研究演示和疼痛模型 – 基本原理、测试和 解释，以及每月举行的疼痛研讨会系列，学员可以与突出的疼痛进行互动 研究人员。这些课程是解决科学严谨性、正确使用 实验设计和分析中的统计、定量素养，以及强化与相关问题 负责任的研究行为。 3) 实践——学员将接受评估、诊断和 通过三个主要途径治疗慢性疼痛患者：1）临床表现的机制 疼痛课程包括一系列针对特定疼痛的评估诊断和治疗的讲座 疼痛患者的亚群/方面（内脏疼痛、头痛、老年疼痛等）； 2）与人进行一对一的互动 临床医生作为培训委员会的成员，这通常与受训者有机会 影子疼痛医生会见、诊断和管理疼痛患者； 3) 参与活动 由管理和预防疼痛挑战 (CHAMPP) 临床疼痛研究中心组织 涉及接触临床疼痛研究、疼痛临床医生和疼痛患者。