Research Training in the Epidemiology of Aging

老龄化流行病学研究培训

• 批准号: 10627454
• 负责人: ANN L GRUBER-BALDINI
• 金额: $ 55.1万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-05-01 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627454
• 关键词: Aging; Epidemiology; Research Training

Abstract As the number of older people increases worldwide, the need for scientists and clinicians in aging research is greater than ever with a critical need for interdisciplinary research on diseases and disabilities that affect a more diverse older population. The objective of years 26-30 of this successful training program is to continue training 5 pre- and 4 post-doctoral fellows to conduct independent and innovative original research in the epidemiology of aging, with an emphasis on the prevention of late life disability and functional decline and the maximization of function in those with existing disabilities and disabling conditions. The program emphasizes four broad substantive areas in which program faculty have gerontologic research experience and are conducting ongoing projects: musculoskeletal epidemiology; neuroepidemiology; genetic epidemiology and genomics; and pharmacoepidemiology. The program prepares trainees to: 1) participate in an interdisciplinary research team under supervision of a primary mentor expert in the epidemiology of aging and secondary mentors expert in epidemiology methods and/or biostatistics, gerontology, and content areas relevant to trainee research; 2) develop a research question, articulate hypotheses, and design and perform an epidemiologic study; 3) become expert in one substantive area relevant to the prevention of disability and functional decline; 4) demonstrate excellence in the conduct of independent, innovative research; 5) gain experience in the presentation of research results, using written, visual, and oral formats; 6) integrate a core curriculum in epidemiology, gerontology, and biostatistics; 7) master the principles of responsible conduct of research and scientific rigor and reproducibility; 8) apply epidemiology of aging methods within clinical contexts; and 9) be prepared for the transition to a research career in academia, government, industry, or non-profit sector using capabilities in the epidemiology of aging. The program is located within the Department of Epidemiology and Public Health (EPH) of the University of Maryland School of Medicine. Major program strengths include: 1) expert faculty in epidemiology of aging, gerontology, biostatistics, and other substantive areas; 2) interdisciplinary training and research opportunities in aging and related areas; 3) graduate training opportunities including advanced coursework through the four supporting doctoral programs; 4) increased training of clinician scientists; 5) commitment to fostering inclusive training; and 6) ability to capitalize on Baltimore/Washington corridor to leverage resources across multiple domains (academia, government, industry, and non-profit). The highly qualified faculty and rich training environment of our program are uniquely suited to provide this interdisciplinary approach needed to train the next generation of scholars with a commitment to epidemiology of aging to find the solutions required to improve the quality of life for older persons. The MPIs bring complementary expertise essential to the success of the program; each has over 20 years of experience in interdisciplinary research, education, and mentorship.

摘要 随着世界范围内老年人数量的增加，对科学家和临床医生进行老龄化研究的需求正在增加。 比以往任何时候都更需要对影响健康的疾病和残疾进行跨学科研究。 更多样化的老年人口。这个成功的培训计划的26-30年的目标是继续 培养5名博士前研究员和4名博士后研究员，以开展独立和创新的原创性研究 老龄化流行病学，重点是预防晚年残疾和功能衰退， 最大限度地发挥现有残疾人和残疾人的功能。该计划强调 四个广泛的实质性领域，其中程序教师有老年学研究经验， 正在进行的项目：肌肉骨骼流行病学;神经流行病学;遗传流行病学和 基因组学和药物流行病学。 该项目为学员做好准备：1）在一名研究人员的监督下参加跨学科研究团队 一级导师是老龄化流行病学专家，二级导师是流行病学方法专家 和/或生物统计学，老年学和与实习生研究相关的内容领域; 2）开发研究 问题，阐明假设，设计和执行流行病学研究; 3）成为一个专家 与预防残疾和功能衰退有关的实质性领域; 4）在 进行独立的，创新的研究; 5）获得研究成果的介绍经验，使用 6）整合流行病学、老年学和生物统计学的核心课程; 7)掌握负责任的研究行为和科学严谨性和可重复性的原则; 8）应用 在临床背景下老化方法的流行病学;和9）准备过渡到研究 在学术界，政府，工业或非营利部门的职业生涯中使用老化流行病学的能力。 该计划是设在流行病学和公共卫生（EPH）的大学的部门， 马里兰州医学院。主要的计划优势包括：1）专家教师在流行病学的老龄化， 老年学、生物统计学和其他实质性领域; 2）跨学科培训和研究机会 在老龄化和相关领域; 3）研究生培训机会，包括通过四个高级课程 支持博士课程; 4）增加临床科学家的培训; 5）致力于促进包容性 培训;以及6）利用巴尔的摩/华盛顿走廊在多个领域利用资源的能力 领域（学术界，政府，工业和非营利组织）。高素质的教师队伍和丰富的培训 我们计划的环境是独特的适合提供这种跨学科的方法需要培养 下一代学者致力于老龄化流行病学，以找到所需的解决方案， 提高老年人的生活质量。MPI带来了成功所必需的补充专业知识 每个人都有超过20年的跨学科研究，教育和指导经验。

项目成果

Whole genome sequence analyses of brain imaging measures in the Framingham Study.

在弗雷明汉研究中，整个基因组序列分析了大脑成像测量。

• DOI: 10.1212/wnl.0000000000004820
• 发表时间: 2018-01-16
• 期刊: Neurology
• 影响因子: 9.9
• 作者: Sarnowski C;Satizabal CL;DeCarli C;Pitsillides AN;Cupples LA;Vasan RS;Wilson JG;Bis JC;Fornage M;Beiser AS;DeStefano AL;Dupuis J;Seshadri S;NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium;TOPMed Neurocognitive Working Group
• 通讯作者: TOPMed Neurocognitive Working Group

A Systematic Review of the Benefits and Risks of Anticoagulation Following Traumatic Brain Injury.

创伤性脑损伤后抗凝治疗的益处和风险的系统评价。

• DOI: 10.1097/htr.0000000000000077
• 发表时间: 2015
• 期刊: The Journal of head trauma rehabilitation
• 作者: Shen,Xian;Dutcher,SarahK;Palmer,Jacqueline;Liu,Xinggang;Kiptanui,Zippora;Khokhar,Bilal;Al-Jawadi,MohammadH;Zhu,Yue;Zuckerman,IleneH
• 通讯作者: Zuckerman,IleneH

Which older adults receive sleep medicine specialty care? Predictors of being seen by a board-certified sleep medicine provider.

哪些老年人接受睡眠医学专业护理？

• DOI: 10.5664/jcsm.8722
• 发表时间: 2020
• 期刊: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
• 作者: Wickwire,EmersonM;Jobe,SophiaL;Parthasarathy,Sairam;Collen,Jacob;Capaldi2nd,VincentF;Johnson,Abree;Vadlamani,Aparna;Levri,JohnM;Scharf,StevenM;Albrecht,JenniferS
• 通讯作者: Albrecht,JenniferS

A cross-sectional pilot study of birth mode and vaginal microbiota in reproductive-age women.

育龄妇女分娩方式和阴道微生物群的横断面试点研究。

• DOI: 10.1371/journal.pone.0228574
• 发表时间: 2020
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Stennett,ChristinaA;Dyer,TyphanyeV;He,Xin;Robinson,CourtneyK;Ravel,Jacques;Ghanem,KhalilG;Brotman,RebeccaM
• 通讯作者: Brotman,RebeccaM

Benefits and risks of anticoagulation resumption following traumatic brain injury.

• DOI: 10.1001/jamainternmed.2014.2534
• 发表时间: 2014-08
• 期刊: JAMA internal medicine
• 影响因子: 39
• 作者: Albrecht JS;Liu X;Baumgarten M;Langenberg P;Rattinger GB;Smith GS;Gambert SR;Gottlieb SS;Zuckerman IH
• 通讯作者: Zuckerman IH