Multi-Component Behavioral Activation, Nutrition, and Activity Intervention for Persons Aging with HIV

摘要 本行政副刊将测试简短(12周)个人化的可行性和可接受性， 行为激活计划专注于减少孤独和增加社交参与度，这将 加强一项计划，增加家庭锻炼，解决老年人营养不良问题 爱滋病毒。它将由远程教练提供。招募对象将包括来自密歇根大学的50岁以上艾滋病毒携带者 如有必要，在巴尔的摩开展Thrive计划和其他艾滋病毒中心。这项工作将在三年内完成 阶段：阶段1：我们将从社区参与战略开始，例如与人员组成的焦点小组 与艾滋病病毒诊断和临床提供者一起，量身定做干预措施。一个社区参与团队将 提供有关交付模式(电话、平板电脑、家庭和/或社区中心)首选项的反馈， 招募战略和小册子、措施、其他学习材料、列入体力活动和 营养模块。第二阶段：我们将与艾滋病毒临床和研究专家在运动、营养和 心理功能，为远程教练量身定做材料和资源的内容 满足PAWH的需求。阶段3：跟踪社区参与并为其量身定做干预措施 PAWH，我们将试点测试10名50岁以上艾滋病毒确诊患者的可行性和可接受性。这 研究将测试急需的干预措施的可行性，以改善以下人群的功能和健康结果 一群老年人中的弱势群体。这是一项探索新干预措施的单组非盲法可行性研究 以支持老年艾滋病毒携带者。如果这种干预看起来是可行的、可接受的，并表明 疗效的初步证据，我们将期待在第三阶段疗效试验中进行评估。它符合以下范围： UM-OAIC，旨在对导致功能障碍的机制进行研究 与老年人普遍存在的慢性病有关；设计新颖、有效的康复 干预措施；并将干预措施转化为在诊所外实施和严格评估(例如， 家、老年中心、健身房)。

Summary This administrative supplement will test the feasibility and acceptability of a brief (12 week) individualized, Behavioral Activation program focused on decreasing loneliness and increasing social engagement, that will be augmented with a program to increase home exercise and address poor nutrition among persons aging with HIV. It will be delivered by remote coaches. Recruitment will include those ages 50+ with HIV from the UM THRIVE program and other HIV centers in Baltimore as necessary. This work will be accomplished in three stages: Stage 1: We will start with community engagement strategies, such as focus groups with persons aging with a HIV diagnosis and clinical providers, to tailor the intervention. A community engagement team will provide feedback on preferences for delivery mode (telephone, tablet, home, and/or at a community center), recruitment strategies and brochures, measures, other study materials, inclusion of the physical activity and nutrition modules. Stage 2: We will work with HIV clinical and research experts in exercise, nutrition, and psychological functioning to tailor the content of the material and resources for the remote coaches in order to meet the needs of PAWH. Stage 3: Following the community engagement and tailoring the intervention for PAWH, we will pilot test feasibility acceptability with 10 persons ages 50+ living with a HIV diagnosis. This study will test the feasibility of a much-needed intervention to improve functioning and health outcomes among a vulnerable group of older adults. It is a single-group unblinded feasibility study to explore a new intervention to support older people aging with HIV. If this intervention appears to be feasible, acceptable, and to show preliminary evidence of efficacy, we will look be to evaluate it in a phase III efficacy trial. It fits into the scope of the UM-OAIC, which aims to conduct research on the mechanisms that underly the functional impairments associated with prevalent chronic diseases in older people; design novel, efficacious rehabilitation interventions; and translate interventions for implementation and rigorous evaluation outside the clinic (e.g., home, senior center, gym).