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Novel Therapies to Enhance Immunity to Cancer

Novel Therapies to Enhance Immunity to Cancer
增强癌症免疫力的新疗法
批准号：
nhmrc : 1122311
负责人：
金额：
$21.75万
依托单位：
The University of Melbourne
依托单位国家：
澳大利亚
项目类别：
Early Career Fellowships
财政年份：
2017
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2017-01-01 至 2020-12-31
来源：
https://researchdata.edu.au/novel-therapies-enhance-immunity-cancer/946921
关键词：
NovelTherapiesEnhanceImmunityCancer

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This project will investigate a new class of targeted drugs called Smac-mimetics. These drugs are proving extremely effective in promoting the death of cancer cells. Here, we aim to better understand how Smac-mimetics work as a cancer therapeutic and how they promote immune responses to cancer. This will enable us to identify combination therapies that elicit both death of the cancer cell and stimulate the immune system to promote tumour clearance.
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