Shared Resource Management

抽象共享资源管理 COHCCC共享资源在支持所有五个项目的癌症研究方面发挥着至关重要的作用 在CC内，从发现的最早阶段到新产品的制造， 用于临床前和1期研究的生物制剂、细胞治疗剂和小分子。 SRM的具体目标： 目标1。提供集中的SR领导和监督，以满足COHCCC的科学需求 成员 目标2.实施有效、标准化的政策和做法，管理使用和评价 SRS. 目标3。响应COHCCC成员当前和未来的科学需求， 增强SR基础设施、服务和运营。 共享资源管理结构监督所有业务方面，包括设备采购 和维护，计费，人员配备，信息研讨会，以及对服务质量的持续监控， 运营效率这是通过SR控制器、其 各自的咨询委员会（SRAC）、共享资源指导委员会（SRSC）、 资源管理（SRA）和共享资源AD。用户反馈来自多个 通过正式和非正式机制提供投入，并为持续调查 COHCCC SR操作。服务项目、工作人员代表领导层的变化和增加新的工作人员代表的工作已在 COHCCC主任和COHCCC EC与AD、SRSC和SRM一起工作的指导 以不断改进为目标。自上次审查以来，重大变化包括 COH和TGen之间SR的整合，高通量筛选和数字成像的增强 服务，将数学肿瘤学纳入生物统计学（BMOC），以及服务的重大升级 和领导结构的综合质谱（IMS）和研究病理学（RP）。临床 微生物组（CMB）SR被提议作为一种新的CCSG资源，以加强 COH和TGen CCC教师，并补充现有的SR，以支持癌症中心的战略目标。 所有CCSG核心的聚合： 2017-21年按收入百分比计算的会员利用率：总计92.7（14.5 MCBC，13 DCT，26.5 CI，32.1 HM，6.6 CCPS，） 会员出版物：637，180，影响因子>10 支持的赠款：共303项（7项ACS，17项CIRM，19项DoD，7项LLS，226项NIH的139项NCI（1项P01，145项R 01，12项U 01））

Abstract Shared Resource Management The COHCCC Shared Resources play a vital role in support of the cancer-focused research of all five programs within the CC, spanning the translational pipeline from the earliest phase of discovery to the manufacture of new biologics, cell therapeutics, and small molecules for preclinical and Phase 1 studies. Specific Aims for SRM: Aim 1. Provide centralized SR leadership and oversight to meet the scientific needs of COHCCC Members. Aim 2. Implement effective, standardized policies and practices that govern the use and evaluation of SRs. Aim 3. Respond to the current and future scientific needs of COHCCC Members via targeted enhancements to SR infrastructure, services, and operations. The Shared Resources management structure oversees all operational aspects including equipment acquisition and maintenance, billing, staffing, informational seminars, and consistent monitoring of service quality and operational efficiency. This is accomplished via cooperative interactions between the SR Directors, their respective Advisory Committees (SRAC), the Shared Resources Steering Committee (SRSC), Shared Resources Administration (SRA), and the AD for Shared Resources. User feedback is provided from multiple inputs, through formal and informal mechanisms, and provides the basis for continual surveying of all aspects of COHCCC SR operations. Changes in service lines, SR leadership, and addition of new SRs are finalized under the direction of the COHCCC Director and COHCCC EC working in conjunction with the AD, SRSC, and SRM with the goal of constant improvement. Since the last review, significant changes have included complete integration of SRs between COH and TGen, enhancement of high throughput screening and digital imaging services, inclusion of mathematical oncology under biostatistics (BMOC), and significant upgrades in services and leadership structure for both Integrated Mass Spectrometry (IMS) and Research Pathology (RP). A Clinical Microbiome (CMB) SR is proposed as a new CCSG resource to enhance collaborative interactions between COH and TGen CCC faculty, and complement existing SRs in support of the strategic goals of the cancer center. Aggregate of all CCSG Cores: Members Utilization by %Revenue 2017–21: 92.7 Total (14.5 MCBC, 13 DCT, 26.5 CI, 32.1 HM, 6.6 CCPS,) Publications by Members: 637, 180 with Impact Factor >10 Grants Supported: 303 Total (7 ACS, 17 CIRM, 19 DoD, 7 LLS, 139 NCI of 226 NIH (1 P01, 145 R01, 12 U01))