Cancer Prevention and Control Research Program

癌症预防与控制研究计划

基本信息

  • 批准号:
    10628433
  • 负责人:
  • 金额:
    $ 4.09万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    1995
  • 资助国家:
    美国
  • 起止时间:
    1995-12-01 至 2028-04-30
  • 项目状态:
    未结题

项目摘要

CANCER PREVENTION AND CONTROL PROGRAM: PROJECT SUMMARY The Virginia Commonwealth University (VCU) Massey Cancer Center (MCC) first introduced its Cancer Prevention and Control (CPC) Program within the Cancer Center Support Grant (CCSG) in 1991. The CPC Program has matured into a highly multidisciplinary nexus of investigators, including population health as well as clinical and basic scientists, and the program continues its emphasis on identifying and mitigating cancer risks. However, since the last CCSG renewal, the CPC Program has recruited multiple new experts in survivorship research, further expanding its impact across the cancer care continuum. The Program is highly focused on addressing MCC’s and the community’s priority disease concerns – lung, gastrointestinal, breast, and prostate cancers – as well as two lifestyles or behaviors significantly driving the cancer burden (tobacco control and obesity prevention). CPC research aligns well with the MCC’s Community-to-Bench framework and its mission, goals, and strategic plans, and the program leads Center efforts actively engaging the community in research. Furthermore, the Center-wide emphasis on reducing disparities is exemplified by many CPC members’ efforts to understand and address inequities among racial/ethnic as well as rural/urban communities, and notably where the two intersect. For instance, within MCC’s catchment area, it is the rural Virginia communities with majority-minority populations of Blacks/African Americans being reported among the nation’s cancer hot spots. Led by Oxana G. Palesh, PhD and Victoria J. Findley PhD, the CPC Program comprises 44 scientists representing 12 departments across the Schools of Medicine, Pharmacy, and the College of Humanities and Science. The program has $6.8M in annual, direct, peer-reviewed funding ($2.5M from NCI, $3.1M from other NIH institutes; and $1.2 from other agencies). In the current project period, CPC members authored 337 cancer- focused research publications reflecting the highly collaborative nature of these scientists; 125 (37%) were intra- programmatic, 46 (14%) were inter-programmatic, 233 (69%) were inter-institutional with 161 (48%) being collaborations with other NCI-designated cancer centers. In addition, the CPC Program has tripled the number of multi-Principal Investigator (MPI) and multi-project awards during the current project period. Their portfolio now includes 16 MPI R01/R21s, two U01s, one UG1, one U54, two P20s, and a Stand Up to Cancer award. The CPC Program also has a growing portfolio of clinic- and community-based interventional studies addressing disparities, supportive care needs, and survivorship, and investigators and since 2016 have enrolled 1,663 individuals to interventional studies and over 18,000 to non-interventional studies. During the next CCSG project period, the CPC Program will continue to anchor its efforts around community-based and community-engaged research to identify and decrease cancer risks, increase cancer screening, and reduce disparate cancer outcomes and inequities for all patients.
癌症预防和控制计划:项目摘要 弗吉尼亚联邦大学(VCU)梅西癌症中心(MCC)首次引入了癌症 1991年癌症中心支持补助金(CCSG)内的预防与控制(CPC)计划。 计划已经成长为研究人员的高度多学科联系,包括人口健康 作为临床和基础科学家,该计划继续强调识别和减轻癌症 风险。但是,自上次CCSG续订以来,CPC计划已招募了多位新专家 生存研究,进一步扩大了其在癌症护理连续体中的影响。该程序高度 专注于解决MCC和社区的优先疾病问题 - 肺,胃肠道,乳房, 和前列腺癌 - 以及两种生活方式或行为,显着推动了癌症伯恩(烟草) 控制和肥胖预防)。 CPC研究与MCC的社区到基础框架非常吻合, 它的使命,目标和战略计划,该计划领导中心努力,积极参与社区 研究。此外,许多CPC成员的核心重点是减少分布的重点 努力了解和解决种族/种族以及粗糙/城市社区之间的不平等,特别是 两个相交的地方。例如,在MCC的集水区内,这是弗吉尼亚州的粗糙社区 在美国癌症热点中,大多数黑人/非洲裔美国人的大多数人口被报道。 由Oxana G. Palesh,博士和Victoria J. Findley博士领导,CPC计划包括44位科学家 代表医学,药房和人文学院的12个部门以及 科学。该计划有680万美元的年度直接,同行评审的资金(NCI的250万美元,来自其他的310万美元 NIH机构;和其他机构的$ 1.2)。在当前的项目期间,CPC成员撰写了337个癌症 - 重点研究出版物反映了这些科学家的高度协作性质; 125(37%)是内部 程序化,46(14%)是截面间的,233(69%)是机构间,161(48%)为 与其他NCI指定的癌症中心的合作。此外,CPC计划增加了两倍 在当前项目期间,多校长研究者(MPI)和多项目奖项的颁奖典礼。他们的投资组合 现在包括16个MPI R01/R21,两个U01,一个UG1,1个U54,两个P20和一个抗癌奖。这 CPC计划还越来越多地针对诊所和社区的介入研究。 差异,支持护理需求和生存以及调查人员,自2016年以来已注册1,663 个人进行介入研究,超过18,000次进行非介入研究。在下一个CCSG项目中 时期,CPC计划将继续扎根于社区和社区参与的努力 研究以识别和降低癌症风险,增加癌症筛查并减少不同的癌症 所有患者的结果和不平等。

项目成果

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Victoria Jane Findlay其他文献

Victoria Jane Findlay的其他文献

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{{ truncateString('Victoria Jane Findlay', 18)}}的其他基金

Lifestyle associated reactive metabolites and their negative impact on breast cancer risk
生活方式相关的反应性代谢物及其对乳腺癌风险的负面影响
  • 批准号:
    10625616
  • 财政年份:
    2022
  • 资助金额:
    $ 4.09万
  • 项目类别:
Lifestyle associated reactive metabolites and their negative impact on breast cancer risk
生活方式相关的反应性代谢物及其对乳腺癌风险的负面影响
  • 批准号:
    10442513
  • 财政年份:
    2022
  • 资助金额:
    $ 4.09万
  • 项目类别:
The effects of time restricted feeding on AGE-RAGE signaling in women at high risk for breast cancer
限时喂养对乳腺癌高危女性 AGE-RAGE 信号的影响
  • 批准号:
    10625580
  • 财政年份:
    2021
  • 资助金额:
    $ 4.09万
  • 项目类别:
The effects of time restricted feeding on AGE-RAGE signaling in women at high risk for breast cancer
限时喂养对乳腺癌高危女性 AGE-RAGE 信号的影响
  • 批准号:
    10304658
  • 财政年份:
    2021
  • 资助金额:
    $ 4.09万
  • 项目类别:

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用于改善前列腺代谢 MR 成像的新硬件和软件开发
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社区采用分子方法进行早期筛查和诊断,通过对非洲裔人群癌症的持续护理来促进公平结果
  • 批准号:
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项目 3:认证 CDK 4/6 抑制剂与放射结合使用作为局部晚期 ER 和 TNBC 的有效治疗策略
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