Balanced and Empowered EaTing (BEET) in Diabetes: A feasibility trial

平衡与增强饮食（BEET）治疗糖尿病：可行性试验

• 批准号: 10738030
• 负责人: Phoutdavone Phimphasone-Brady
• 金额: $ 16.98万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10738030
• 关键词: Acceleration; Address; Adherence; Adoption; Adult; Affect; Attitude; Behavior; Behavioral; Behavioral Research; Biological; Blood Glucose; Body mass index; Caring; Chronic Disease; Clinic; Clinical; Clinical Trials Design; Cognitive Therapy; Colorado; Data; Data Analyses; Data Collection; Diabetes Mellitus; Disease; Disease Management; Eating; Eating Behavior; Eating Disorders; Education; Educational Intervention; Effectiveness; Endocrine; Evaluation; Evidence based intervention; Evidence based practice; Evidence based program; Exercise; Fasting; Future; Glycosylated hemoglobin A; Goals; Health; Health Personnel; Hyperphagia; Hypertriglyceridemia; Individual; Intake; Intervention; Interview; K-Series Research Career Programs; Laboratories; Learning Skill; Maintenance; Measures; Mediating; Medical; Mental Health; Mentors; Mentorship; Metabolic; Metabolic Control; Methods; Neuroendocrinology; Non-Insulin-Dependent Diabetes Mellitus; Outcome; Participant; Patient Outcomes Assessments; Patients; Persons; Pharmacology; Prevention approach; Procedures; Protocols documentation; Provider; Psyche structure; Psychiatry; Psychologist; Randomized; Reach, Effectiveness, Adoption, Implementation, and Maintenance; Readiness; Recommendation; Replicating Effective Programs; Reporting; Research; Research Training; Risk; Risk Factors; Sample Size; Self Efficacy; Services; Structure; Surveys; Training; Translations; Universities; analytical method; arm; behavioral health; behavioral health intervention; biobehavior; career; comparative; design; diabetes distress; diabetes self-management; diet and exercise; dissemination science; effectiveness/implementation trial; empowerment; evidence base; experience; feasibility testing; feasibility trial; fruits and vegetables; glucose monitor; glycemic control; high body mass index; implementation evaluation; implementation framework; implementation science; implementation strategy; improved; interest; intervention effect; member; novel; participant enrollment; pilot test; primary care clinic; primary outcome; professor; programs; recruit; resilience; screening; self help; skills; treatment strategy

PROJECT SUMMARY Up to 20% - or nearly 7,000,000 – adults with diabetes (T2DM) concurrently experience disordered eating behaviors (DEBs, e.g., significant overeating with loss of control), resulting in higher body mass index and lower adherence to diet and exercise recommendations. DEBs are often disregarded by medical providers and patients, and therefore undertreated in clinical settings. Research is limited on whether treatment for DEBs impacts diabetes self-management and glycemic functioning. To address this, we developed the Balanced and Empowered EaTing (BEET) in Diabetes, or the BEET Diabetes Program, a novel cognitive-behavioral therapy- based program to designed to specifically treat DEBs in T2DM and improve diabetes self-management. By designing with implementation science methods and engaging integrated behavioral health providers (BHPs) in real clinical settings, we aim to 1) address an important treatment need for people with T2DM and concurrent DEBs, and 2) improve the integration of BHPs in collaborative diabetes care in clinical settings. Candidate and Mentors: I am an Assistant Professor in the Department of Psychiatry at the University of Colorado. As a clinical health psychologist with training in implementation science methods, my program of research aims to implement and evaluate evidence-based programs for mental health conditions that could worsen diabetes and other endocrinopathies. I have built a strong mentorship team to guide my training including primary mentor, Dr. C. Neill Epperson (neuroendocrinology of risk and resilience), and co-mentor, Dr. Bethany Kwan (dissemination & implementation science). Research and Training: I propose short term scientific, educational, and training goals that will build upon my prior research training through three research aims: 1) engage BHPs to refine the BEET Diabetes Program for implementation in clinical settings, 2) evaluate the feasibility of the BEET Diabetes Program, and 3) determine the reach and estimate the effectiveness of the BEET Diabetes Program on patient-reported and clinical outcomes. The complementary training goals to establish scientific independence through training in: 1) advanced mixed-methods analytical skills by learning configurational comparative methods for implementation science, 2) clinical trial design for behavioral research and longitudinal data analysis, and 3) methods for biological data collection, analysis, and interpretation in T2DM. Summary: DEBs in T2DM are a serious yet under-recognized clinical problem. There is a significant dearth of research examining associated risk factors and treatments of DEBs in T2DM. My ultimate career goal is to transform our approach to the prevention of endocrine- and metabolic-conditions by developing and implementing evidence-based mental/behavioral programs in clinical settings. Completion of this career development award will accelerate my path towards becoming a national expert in the biobehavioral management of endocrinopathies.

项目总结 多达20%--即近700万--患有糖尿病(T2 DM)的成年人同时患有进食障碍 行为(Debs，例如，严重暴饮暴食并失去控制)，导致较高的身体质量指数和较低的 坚持饮食和锻炼的建议。Debs经常被医疗提供者忽视，而且 患者，因此在临床环境中未得到充分治疗。关于Debs的治疗方法的研究很有限 影响糖尿病自我管理和血糖调节功能。为了解决这个问题，我们开发了平衡和 糖尿病的强化进食(甜菜)，或甜菜糖尿病计划，一种新的认知-行为疗法- 基于专门治疗T2 DM患者Debs和改善糖尿病自我管理的计划。通过 使用实施科学方法进行设计，并与综合行为健康提供者(BHP)接洽 真实的临床环境，我们的目标是1)满足T2 DM患者和并发患者的重要治疗需求 Debs，以及2)改善BHP在临床环境下协作式糖尿病护理中的整合。 候选人和导师：我是加州大学精神病学系的助理教授 科罗拉多州。作为一名接受过实施科学方法培训的临床健康心理学家，我的计划 研究旨在实施和评估针对精神健康状况的循证计划，这些计划可能 加重糖尿病和其他内分泌疾病。我建立了一支强大的指导团队来指导我的培训，包括 主要导师C·尼尔·埃普森博士(风险和复原力的神经内分泌学)和共同导师贝瑟尼博士 传播与实施学。 研究和培训：我提出短期的科学、教育和培训目标，这些目标将建立在我的 通过三个研究目标进行前期研究培训：1)聘请BHPS完善甜菜糖尿病计划 在临床环境中的实施，2)评估甜菜糖尿病计划的可行性，以及3)确定 甜菜糖尿病计划对患者报告和临床的可达性和有效性评估 结果。通过培训建立科学独立性的补充培训目标：1) 通过学习用于实现的构型比较方法的高级混合方法分析技能 科学，2)行为研究和纵向数据分析的临床试验设计，以及3)方法 2型糖尿病患者生物学数据的收集、分析和解释。 摘要：T2 DM的Debs是一个严重但未被充分认识的临床问题。有一个严重的匮乏 2型糖尿病合并糖尿病相关危险因素及治疗的研究。我的最终职业目标是 改变我们预防内分泌和代谢疾病的方法 在临床环境中实施循证心理/行为计划。完成这一职业生涯 发展奖将加速我成为国家生物行为专家的道路 内分泌疾病的管理。