Balanced and Empowered EaTing (BEET) in Diabetes: A feasibility trial

项目摘要 高达20% -或近7，000，000-成人糖尿病（T2 DM）同时经历饮食失调 行为（DEB，例如，显著暴饮暴食，失去控制），导致体重指数较高， 坚持饮食和锻炼建议。DEB经常被医疗提供者忽视， 患者，因此在临床环境中治疗不足。关于DEB的治疗是否 影响糖尿病自我管理和血糖功能。为了解决这个问题，我们开发了平衡和 授权饮食（BEET）糖尿病，或BEET糖尿病计划，一种新的认知行为疗法- 该计划旨在专门治疗T2 DM中的DEB并改善糖尿病自我管理。通过 采用实施科学方法进行设计，并让综合行为健康提供者（BHP）参与， 在真实的临床环境中，我们的目标是：1）满足T2 DM患者的重要治疗需求， DEB，和2）改善BHP在临床环境中协作糖尿病护理中的整合。 候选人和导师：我是明尼苏达大学精神病学系的助理教授， 科罗拉多。作为一名接受过实施科学方法培训的临床健康心理学家， 研究旨在实施和评估基于证据的精神健康状况计划， 使糖尿病和其他内分泌疾病恶化。我已经建立了一个强大的导师团队来指导我的培训，包括 主要导师C博士Neill Epperson（风险和恢复力的神经内分泌学）和共同导师Bethany博士 传播与实施科学（Dissemination & Implementation Science） 研究和培训：我提出了短期的科学，教育和培训目标，这些目标将建立在我的 通过三个研究目标进行事先的研究培训：1）让BHP完善BEET糖尿病计划， 在临床环境中的实施，2）评估BEET糖尿病计划的可行性，以及3）确定 BEET糖尿病计划对患者报告和临床的影响 结果。通过以下方面的培训建立科学独立性的补充培训目标：1） 通过学习实施的配置比较方法，提高混合方法分析技能 科学，2）行为研究和纵向数据分析的临床试验设计，以及3） 2型糖尿病的生物学数据收集、分析和解释。 总结：T2 DM中的DEB是一个严重但未被认识到的临床问题。有一个显着缺乏 研究检查T2 DM中DEB的相关风险因素和治疗。我职业生涯的终极目标是 改变我们的方法来预防内分泌和代谢条件， 在临床环境中实施循证心理/行为方案。完成这一职业生涯 发展奖将加速我的道路，成为一个国家的专家，在生物行为 内分泌疾病的管理。

PROJECT SUMMARY Up to 20% - or nearly 7,000,000 – adults with diabetes (T2DM) concurrently experience disordered eating behaviors (DEBs, e.g., significant overeating with loss of control), resulting in higher body mass index and lower adherence to diet and exercise recommendations. DEBs are often disregarded by medical providers and patients, and therefore undertreated in clinical settings. Research is limited on whether treatment for DEBs impacts diabetes self-management and glycemic functioning. To address this, we developed the Balanced and Empowered EaTing (BEET) in Diabetes, or the BEET Diabetes Program, a novel cognitive-behavioral therapy- based program to designed to specifically treat DEBs in T2DM and improve diabetes self-management. By designing with implementation science methods and engaging integrated behavioral health providers (BHPs) in real clinical settings, we aim to 1) address an important treatment need for people with T2DM and concurrent DEBs, and 2) improve the integration of BHPs in collaborative diabetes care in clinical settings. Candidate and Mentors: I am an Assistant Professor in the Department of Psychiatry at the University of Colorado. As a clinical health psychologist with training in implementation science methods, my program of research aims to implement and evaluate evidence-based programs for mental health conditions that could worsen diabetes and other endocrinopathies. I have built a strong mentorship team to guide my training including primary mentor, Dr. C. Neill Epperson (neuroendocrinology of risk and resilience), and co-mentor, Dr. Bethany Kwan (dissemination & implementation science). Research and Training: I propose short term scientific, educational, and training goals that will build upon my prior research training through three research aims: 1) engage BHPs to refine the BEET Diabetes Program for implementation in clinical settings, 2) evaluate the feasibility of the BEET Diabetes Program, and 3) determine the reach and estimate the effectiveness of the BEET Diabetes Program on patient-reported and clinical outcomes. The complementary training goals to establish scientific independence through training in: 1) advanced mixed-methods analytical skills by learning configurational comparative methods for implementation science, 2) clinical trial design for behavioral research and longitudinal data analysis, and 3) methods for biological data collection, analysis, and interpretation in T2DM. Summary: DEBs in T2DM are a serious yet under-recognized clinical problem. There is a significant dearth of research examining associated risk factors and treatments of DEBs in T2DM. My ultimate career goal is to transform our approach to the prevention of endocrine- and metabolic-conditions by developing and implementing evidence-based mental/behavioral programs in clinical settings. Completion of this career development award will accelerate my path towards becoming a national expert in the biobehavioral management of endocrinopathies.