2023 Cell Growth and Proliferation Gordon Research Conference and Seminar

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SUMMARY This proposal is a request for support from the NCI for partial support of the Gordon Research Conference (GRC) “Cell Growth and Proliferation: Cell Cycle and Proliferation in Development and Cancer.” The conference will gather 150-200 graduate students, postdoctoral fellows, staff scientists, junior and senior faculty, lab leaders in industry and government for discussions of their most recent unpublished discoveries. The Conference will focus on mechanisms of normal cell proliferation control, the many cell cycle variations required for normal growth, and the variety of abnormal cell cycle perturbations in cancer and other proliferative diseases. The program format is an approximately equal mix of invited speakers with speakers selected from abstract submitted in the spring of 2023 with an emphasis on broad representation of speakers from multiple disciplines, career stages, demographic and geographic backgrounds. The Chair and Vice Chair are specifically committed to creating a diverse and inclusive conference that reflects the breadth of cell cycle control and fundamental cancer cell biology research and that showcases the contributions of both junior and senior members of the field; 44% of the confirmed invited speakers are women and all discussants are women. Topics of formal research sessions planned include an opening session focused on Protein Degradation in Development and Cancer and additional sessions including 1) Cell Cycle Machinery and Cell Division, 2) Proliferation and Genome Stability, 3) Mechanisms of Cell Cycle Progression and Quiescence, 4) Driving the Cell Cycle, 4) Targeting CDKs in Cancer, 5) Signaling Pathways in Development and Cancer, 6) Genome Integrity and Immunity, and 7) System biology and Genomics. In addition, there will be four poster sessions and ample unstructured time for informal networking. We will also use funding to partially support the affiliated Gordon Research Seminar (GRS). The GRS is a 1.5day event that immediately precedes the GRC organized by and for postdocs and students to present their work and engage in career development. Both events will be held at Mount Snow Resort, West Dover, Vermont from July 9-14, 2023, and the GRC is a major conference relatively unique in its breadth because it brings together researchers focused on basic and translational biology from academic and industry settings.