Resilient HIV Implementation Science with Sexual and Gender Minority Youths using Evidence (RISE) Clinical Research Center

项目总结 性少数和性别少数(与男性发生性关系的年轻男子[基督教青年会]和年轻的变性妇女 [YTW])有艾滋病毒风险和艾滋病毒携带者的青少年(15-24岁)在国际社会中的代表性很低 实施科学(IS)研究。有弹性的艾滋病毒实施科学的首要目标是 SGM青少年使用证据(RISE)临床研究中心正在为 开发和开展信息系统研究，以改进艾滋病毒预防和护理连续体(PHCC)。具有战略意义的 规划过程，包括全面审查我们的启联在加速和最大限度地利用 将数字健康融入实践，提高与SGM青年进行IS研究的科学能力， 翻译研究结果，以便为国家和全球关于SGM青年临床治疗的指南提供信息 为告知这项建议而进行的。一份包含四个主题的愿景声明-伙伴关系中的平等 对于访问、针对青年量身定做的干预、严谨的研究和协作能力 可持续发展塑造了我们的工作。瑞星临床研究中心是一个多学科的研究小组 由马里兰大学巴尔的摩分校的行政核心和五项临床研究组成 代表实施伙伴和社区艾滋病毒网络的实施地点(CRPS) 西非、东部和南部非洲的服务提供者(CBSP)：(1)人口健康倡议中心， 尼日利亚(CPhI)；(2)尼日利亚人类病毒学研究所(IHVN)；(3)#年卫生与发展伙伴 非洲，肯尼亚(PHDA)；(4)人民发展中心(CEDEP)；和(5)国际中心 卫生教育生物安全，赞比亚(Ciheb赞比亚)。加起来，我们有超过15年的领导力 在设计、实施和开展与SSA和SGM青年的卫生服务研究方面的经验 美国(US)。在多位PI的领导下，Man Charurat博士，Lisa Hightow-Weidman 医学博士，Sylvia Adebajo，博士，青年和SGM服务提供和政策制定多学科调查 团队与AHISA在每个国家的代表一起，包括Kate Muessig博士，-行为 科学家，Nadia Sam-Agudu医学博士-AHISA尼日利亚，宽戈·阿戈特博士，M.P.H-AHISA肯尼亚，Nora Rosenberg博士-AHISA马拉维，和Maurice Musheke博士-AHISA赞比亚，我们将参加 适应和定制数字健康平台，并进行其实施，以支持 在SGM青年中的PCC。用于法规遵从性、数据管理、数据质量、 整个CRPS的数据分析促进了CRC的效率和质量的提高。协作能力 AHISA、卫生部和青年咨询委员会在社区参与方面的能力 发展和可持续发展将促进儿童权利委员会在当地和全球的影响。

PROJECT SUMMARY Sexual and gender minority (young men who have sex with men [YMSM] and young transgender women [YTW]) youths (ages 15-24 years) at risk of and living with HIV are poorly represented in international implementation science (IS) research. The overarching goal of Resilient HIV Implementation Science with SGM Youths using Evidence (RISE) Clinical Research Center is to make significant contributions to the development and conduct of IS studies to improve HIV prevention and care continuum (PHCC). A strategic planning process including a comprehensive review of our CRC's role in accelerating and maximizing the integration of digital health into practice, increasing the scientific capacity for IS research with SGM youths, translating findings to inform national and global guidelines on clinical management of SGM youths was conducted to inform this proposal. A vision statement encompassing four Themes – Equity in Partnerships for Access, Youth-tailored Intervention, Rigor IS Research, and Collaboration Capacity for Sustainability shapes our work. The RISE Clinical Research Center is a multidisciplinary research group composed of an administrative core at the University of Maryland Baltimore and five clinical research performing sites (CRPSs) that represent a network of implementing partners and community-based HIV service providers (CBSPs) in West, East, and Southern Africa: (1) Centre for Population Health Initiatives, Nigeria (CPHI); (2) Institute of Human Virology, Nigeria (IHVN); (3) Partners for Health & Development in Africa, Kenya (PHDA); (4) Centre for the Development of People (CEDEP); and (5) Center for International Health Education Biosecurity, Zambia (Ciheb Zambia). Together, we have over fifteen years of leadership experience in the design, implementation, and conduct of health service studies with SGM youths in SSA and the United States (US). Under the leadership of the multiple PIs, Man Charurat Ph.D, Lisa Hightow-Weidman M.D., Sylvia Adebajo, PhD, a youth and SGM service delivery and policy-making multidisciplinary investigative team together with representatives from AHISA in each country including Kate Muessig, Ph.D, – a behavioral scientist, Nadia Sam-Agudu M.D. – AHISA Nigeria, Kwango Agot Ph.D, M.P.H – AHISA Kenya, Nora Rosenberg, Ph.D. – AHISA Malawi, and Maurice Musheke, Ph.D. M.P.H – AHISA Zambia, we will participate in the adaptation and customization of a digital health platform and conduct its implementation to support PHCC among SGM youths. Centralized resources for regulatory compliance, data management, data quality, and data analysis across the CRPSs promote RISE CRC's efficiency and quality. Collaboration capacity with AHISA, health ministries, and youth advisory boards for community engagement, IS capacity development, and sustainability will promote RISE CRC's impact locally and globally.