Establishing Readiness of Dental Professionals in Practice-Based Research and Inter-Professional Care

使牙科专业人员做好基于实践的研究和跨专业护理的准备

基本信息

批准号：
10755140
负责人：
ANGELA BRUZZANITI
金额：
$ 69.44万
依托单位：
INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-13 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10755140
关键词：
Address Affect Arthralgia Autoantibodies Award Awareness Basic Science Behavior Biological Markers Biopsy Career Mobility Caring Characteristics Clinical Clinical Research Clinical Research Protocols Clinical Sciences Collaborations Communication Community Practice Competence Consent Consultations Critical Thinking Dental Dental Clinics Dental General Practice Dental Research Dental Schools Dental Students Diagnosis Disease Disease Management Disease Progression Disease susceptibility Dryness Early Diagnosis Educational Curriculum Effectiveness Electronic Health Record Faculty Fatigue Fellowship Fibromyalgia Foundations Funding Opportunities Goals Health Health Personnel Health Professional Healthcare Immunoglobulin G Indiana Individual Informatics Knowledge Lead Longitudinal Studies Managed Care Measurable Measures Medical Medical Research Medicine Mentors Mentorship Minor salivary gland structure National Institute of Dental and Craniofacial Research Nursing Faculty Oral Oral Characters Oral Examination Oral health Outcome Outcome Measure Participant Patient-Focused Outcomes Patients Persons Pharmacists Pharmacy facility Play Postdoctoral Fellow Practice based research Predisposition Readiness Research Research Activity Research Personnel Research Project Grants Research Training Role Saliva Salivary Schedule School Dentistry Serum Shapes Sjogren&apos s Syndrome Standardization Students Teacher Professional Development Testing Tissues Training Training and Education Translating Translational Research Universities Woman Writing Xerostomia biomarker identification biomarker selection biomarker validation care coordination career development clinical practice college design disorder risk early detection biomarkers education research evidence base experience follow-up implementation protocol improved indexing inter-institutional medical schools multidisciplinary next generation patient oriented research peer practice setting practice-based research network pre-doctoral predictive marker programs protein biomarkers randomized, controlled study recruit research study rheumatologist saliva diagnostic shared decision making skill acquisition skills telehealth treatment planning virtual health willingness

项目摘要

Project Summary Practice-based research (PBR) has demonstrated effectiveness to integrate evidence-based care into clinical practice, enhance the generalizability of research findings and conduct longitudinal studies not possible through traditional randomized controlled studies. The PBR Networks (PBRN) in medicine began in 1970 and have played a crucial role in advancing medical research findings and translating research evidence to practice settings to enhance patient outcomes. The National Institute of Dental and Craniofacial Research (NIDCR) established the Dental Practice-Based Research Network in 2005 and it is now considered to be the largest dental PBRN in the world. However, PBR experiences have yet to become part of the dental predoctoral/postdoctoral curriculum. According to NIDCR, it is essential to ‘engage dental students in research activities and incorporate evidence-based principles into the dental curriculum to enhance their critical thinking skills to evaluate and incorporate new knowledge into practice.’ In this application, the Indiana University (IU) School of Dentistry (IUSD) investigators with expertise in basic science, PBR, informatics, and salivary diagnostics have established collaborations with the Indiana Clinical and Translational Science Institute (CTSI), IU School of Medicine (IUSM), Purdue College of Pharmacy, Regenstrief Institute, Inc. and Indiana Health Information Exchange to advance clinical research training of dental clinical faculty and trainees, and strengthen research mentoring partnership amongst students, clinical faculty and researchers. We will advance knowledge of salivary and serum biomarkers in identifying dental patients susceptible to Sjögren’s Disease (SD), thus improving patient outcomes and management of patients at risk for SD and manage through interprofessional communication and collaboration of dental clinicians (DC), pharmacists, rheumatologists, and patients. This application is significant because it seeks to 1) advance the knowledge and skills of next-generation DCs to conduct and lead PBR, 2) facilitate interprofessional communication and care via virtual health platforms to address dental patients’ conditions such as SD that require multidisciplinary expertise for timely diagnosis and management and 3) develop a salivary hypofunction index in combination with salivary biomarkers to detect patients susceptible to SD thus improving shared decision making and management of patients at risk for SD. The outcomes include measurable increases in DC students and faculty completing clinical research and mentoring training and participation in the proposed PBR study, validation of biomarkers for early detection of SD in PBR settings, and improvement in coordinating care with other health care providers. The proposed research is significant because it lays the foundation for multidisciplinary teams to diagnose and manage individuals affected with SD in community practice settings and reduce current delays in diagnosis due to fragmented and siloed dental-medical care.

项目摘要基于实践的研究（PBR）证明了将基于证据的护理整合到临床上的有效性实践，提高研究结果的普遍性，并通过传统的随机对照研究。医学中的PBR网络（PBRN）始于1970年，已有在推进医学研究发现并将研究证据转化为实践中起着至关重要的作用设置以增强患者的预后。国家牙科与颅面研究所（NIDCR）在2005年建立了基于牙科实践的研究网络，现在被认为是最大的世界上的牙齿PBRN。但是，PBR经验尚未成为牙科的一部分前/博士后课程。根据NIDCR的说法，“让牙科学生参与研究至关重要活动并将基于证据的原则纳入牙科课程，以增强他们的批判性思维评估并将新知识纳入实践的技能。’在本应用程序中，印第安纳大学（IU）牙科学院（IUSD）研究人员具有基础科学专业知识，PBR，信息信息和唾液的专业知识诊断已经与印第安纳州临床和转化科学研究所（CTSI）建立了合作 IU医学院（IUSM），普渡大学药学院，雷金特里夫研究所和印第安纳州健康信息交流以推进牙科临床教师和学员的临床研究培训，以及力量研究指导学生，临床教师和研究人员之间的伙伴关系。我们将提高知识唾液和血清生物标志物在识别易感Sjögren病（SD）的牙科患者时改善患有SD风险的患者的患者预后和管理，并通过跨专业管理牙科临床医生（DC），药剂师，风湿病学家和患者的沟通与协作。这应用很重要，因为它试图1）提高下一代DC的知识和技能进行和铅PBR，2）通过虚拟健康平台促进跨专业的沟通和护理解决牙科患者的状况，例如SD，需要及时诊断和管理和3）与唾液生物标志物结合使用唾液功能低下指数来检测患者容易受到SD的影响，从而改善了有SD风险的患者的共同决策和管理。结果包括DC学生的可测量增加以及完成临床研究的教职员工指导培训和参与拟议的PBR研究，验证生物标志物以及早发现 SD在PBR环境中，以及与其他医疗保健提供者的协调护理改进。提议研究很重要，因为它为多学科团队奠定了诊断和管理的基础在社区实践环境中受到SD影响的个人，并减少由于分散和孤立的牙科医疗护理。