Core A - Administrative Core

核心A--摘要 核心A(行政)的作用是提供领导，促进凝聚力，并确保对 AD和ADRD中靶向反应性星形胶质细胞的P01策略在激励和培养的道路上 P01团队之间的互动，核心A将提供共同的资源，管理预算问题，并履行 对大学和NIH/NIA的行政义务。这些服务将允许项目和核心 将重点放在科学上，重新定义反应性星形胶质细胞在病理生理学中的作用 阿尔茨海默病(AD)和相关痴呆症(ADRD)。核心A的目标是：(1)提供协调的 和连贯的基础设施，以加强科学活动。(2)监管动物栖息地和 AAV试剂的生产/表征。(3)提供财政管理和行政支持。 行政核心将促进及时和一致的监督，以便项目和核心能够运作 一起作为一个单元来研究ADRDS中的反应性星形胶质细胞信号。

CORE A – ABSTRACT SUMMARY The role of Core A (Administrative) is to provide leadership, promote cohesion, and ensure fiscal oversight for the P01 Strategies for Targeting Reactive Astrocytes in AD and ADRD. En route to stimulating and fostering interactions among the P01 team, Core A will provide common resources, manage budgetary issues, and fulfill administrative obligations to the University and to the NIH/NIA. These services will allow the Projects and Cores of the P01 to focus on the Science and reconceptualize the role of reactive astrocytes in the pathophysiology of Alzheimer’s disease (AD) and related dementias (ADRDs). The Aims of Core A are: (1) Provide coordinated and coherent infrastructure that enhances scientific activities. (2) Oversee animal colonies and production/characterization of AAV reagents. And (3) provide fiscal management and administrative support. The Administrative Core will facilitate timely and consistent oversight so that Projects and Cores can work together as a unit to study reactive astrocyte signaling in ADRDs.