Developing a Dyadic Survivorship Intervention for Black Women with Breast Cancer and Their Informal Caregivers

为患有乳腺癌的黑人女性及其非正式护理人员制定二元生存干预措施

• 批准号: 10901074
• 负责人: Tess Thompson
• 金额: $ 9.05万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-25 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10901074
• 关键词: Address; Adherence; Black race; Breast Cancer Patient; Breast Cancer survivor; Cancer Center; Cancer Patient; Cancer Survivorship; Caregiver support; Caregivers; Caring; Characteristics; Clinical; Consolidated Framework for Implementation Research; Data; Family; Family member; Feasibility Studies; Feedback; Female; Focus Groups; Foundations; Friends; Goals; Health; Individual; Intervention; Interview; Long Term Survivorship; Malignant Neoplasms; Measures; Methods; Outcome; Patient-Focused Outcomes; Patients; Persons; Positioning Attribute; Psychology; Quality of life; Randomized, Controlled Trials; Reduce health disparities; Reporting; Research; Sampling; Services; Spouse Caregiver; Spouses; Teleconferences; Testing; Time; Work; acceptability and feasibility; active method; black patient; black women; brief intervention; caregiving; clinical care; design; experience; health care service utilization; improved; improved outcome; informal caregiver; malignant breast neoplasm; member; novel; physical conditioning; pilot test; programs; psychosocial; recruit; remote delivery; satisfaction; survivorship; therapy design; therapy development

1 Breast cancer patients and their informal caregivers often report unmet psychosocial, relational, and physical 2 health needs that persist into long-term survivorship. Although dyadic interventions have shown promise in 3 improving outcomes for patients and caregivers, few existing interventions are designed for Black patients and 4 the female family members and friends who provide the majority of unpaid care and support. This study will 5 develop a novel dyadic intervention delivered via video teleconferencing (VTC) to Black breast cancer patients 6 and their female informal caregivers to improve quality of life and relationship outcomes during the transition to 7 long-term survivorship. This proposal is directly responsive to NCI’s priorities about caregiving and cancer 8 survivorship and will lay the foundation for a randomized controlled trial of a first-of-its-kind dyadic intervention. 9 First, we will build on our previous and current work with Black breast cancer patients and their informal 10 caregivers by asking dyads to evaluate potential intervention content. Next, we will design for dissemination by 11 interviewing stakeholders to identify facilitators and barriers to implementing dyadic survivorship interventions 12 in clinical care. Finally, we will develop a brief intervention and evaluate its acceptability and feasibility. The 13 aims of this proposal are as follows: Aim 1: Evaluate the potential domains and characteristics of a brief 14 VTC intervention to improve quality of life for Black breast cancer patients and female informal 15 caregivers during the transition to long-term survivorship. We will solicit qualitative and quantitative 16 feedback from both members of dyads individually and together (N = 20 dyads) about themes, domains, and 17 characteristics of a culturally appropriate patient- and caregiver-centered VTC survivorship intervention. Aim 2. 18 Identify facilitators and barriers to implementing dyadic survivorship interventions in clinical care. We 19 will design for dissemination by conducting interviews (N = 15) with stakeholders the cancer center based on 20 the Consolidated Framework for Implementation Research. A directed thematic analysis will allow us to 21 understand barriers and facilitators to delivering dyadic interventions in clinical care. Aim 3. Evaluate a brief 22 VTC intervention in a pilot feasibility study (N = 20 dyads). Based on the formative research in Aims 1 and 23 2, we will develop a 4-session intervention delivered remotely by psychology service staff at the cancer center 24 around the time patients complete active treatment and transition to long-term survivorship. We will collect 25 quantitative and qualitative feasibility data from patients and their female caregivers about satisfaction and 26 intervention acceptability. We will also pilot test the assessment battery, including validated measures of 27 relationship outcomes, health care utilization, and quality of life for both dyad members. Upon completion of 28 this project, our team will be well-positioned to test the intervention in a larger trial. The ultimate goal of this 29 research program is to reduce health disparities by improving outcomes for Black breast cancer patients and 30 their female caregivers.

1乳腺癌患者和他们的非正式照顾者经常报告未得到满足的心理社会，关系和身体 2健康需求持续到长期生存。尽管二元干预在以下方面显示出了希望： 3改善患者和护理人员的结局，很少有现有的干预措施是为黑人患者设计的， 4.提供大部分无偿照顾和支持的女性家庭成员和朋友。本研究将 5开发一种通过视频电话会议（VTC）向黑人乳腺癌患者提供的新型二元干预 6和她们的女性非正式照顾者，以改善生活质量和关系的结果，在过渡到 7长期生存这一建议是直接响应NCI的优先事项有关乳腺癌和癌症 8生存率，并将奠定基础的随机对照试验的第一个同类的二元干预。 9首先，我们将建立在我们以前和目前的工作与黑人乳腺癌患者和他们的非正式 10照顾者通过要求二对评估潜在的干预内容。接下来，我们将通过 11次访谈利益相关者，以确定实施二元生存干预措施的促进因素和障碍 12临床护理最后，我们将制定一个简短的干预措施，并评估其可接受性和可行性。的 本提案的目标如下：目标1：评估简报的潜在领域和特征 14 VTC干预改善黑人乳腺癌患者和女性非正式生活质量 在向长期生存过渡期间的15名护理人员。我们将征求定性和定量 16个反馈，分别来自二人组的两个成员，以及一起（N = 20二人组）关于主题，领域， 文化上适当的以患者和患者为中心的VTC生存干预的17个特征。目标2. 18确定在临床护理中实施二元生存干预的促进者和障碍。我们 19人将通过与癌症中心的利益相关者进行访谈（N = 15）进行传播设计， 20执行情况研究综合框架。有针对性的主题分析将使我们能够 21了解在临床护理中提供二元干预的障碍和促进因素。目标3.评估一份简报 22 VTC干预试点可行性研究（N = 20对）。基于目标1和 232，我们将开发一个由癌症中心的心理服务人员远程提供的4次干预 大约24个患者完成积极治疗并过渡到长期生存。我们将收集 来自患者及其女性护理人员的25个定量和定性可行性数据， 26篇可接受性我们还将对评估组合进行试点测试，包括 27关系的结果，医疗保健利用，和生活质量的两个二元组成员。完成后 28这个项目，我们的团队将有能力在更大的试验中测试干预措施。这个项目的最终目标 29项研究计划旨在通过改善黑人乳腺癌患者的预后来减少健康差距， 30、女性护理员