Implementation of PrEP Care Among Women in Family Planning Clinics

项目总结/摘要 在艾滋病毒预防工作中，黑人妇女经常被忽视，尽管她们有一种 艾滋病毒感染率在所有亚群中最高，仅次于男男性行为者。暴露前 预防性治疗（PrEP）是一种安全有效的日常药物，适用于有感染艾滋病毒风险的人。但数据 这表明，与妇女的需求相比，PrEP的使用存在很大的不平等。这项拟议的研究将 评估实施战略，以解决多层次的障碍，并增加 伊利诺伊州计划生育诊所的黑人顺性别妇女。 我们团队的初步工作已经确定了女性PrEP优化的成功策略， 增强保留和吸收（POWER UP）。POWER Up实施战略解决了 PrEP吸收和包括：1）常规PrEP教育2）标准化提供者培训，3）电子健康记录 (EHR)工具;和4）PrEP导航。这些策略尚未在计划生育诊所进行研究， 大量的黑人cisgender妇女。因此，我们利用实施科学的研究方法， 建议在计划生育范围内实施和评估POWER UP战略的影响， 伊利诺伊州（PPIL）健康中心设置，以改善黑人顺性别妇女的PrEP护理连续成果。通过 在PPIL健康中心实施POWER Up战略，我们寻求解决以下方面的知识差距差距： 确定有效的战略，以增加黑人cisgender妇女之间的PrEP吸收。 这项拟议的研究旨在： 1.调整POWER UP实施战略，使黑人妇女参与PrEP护理连续体， 芝加哥的八家计划生育诊所 2.确定POWER Up在芝加哥艾滋病高发区的八个PPIL站点的有效性 地区;以及， 3.评估和记录实施成果，并报告与成功实施有关的主要障碍和促进因素 干预措施的实施 这项研究的结果将提供深入了解实施战略，可以支持有效的复制 在800个计划生育健康中心和其他提供计划生育服务的健康中心， 在全国范围内向更多的高危妇女提供服务。

PROJECT SUMMARY/ABSTRACT Cisgender Black women are frequently overlooked in HIV prevention efforts even though they have one of the highest incidences of HIV among all subpopulations, second only to men who have sex with men. Pre-exposure prophylaxis (PrEP) is a safe and effective daily medication for those at risk for HIV infection. However, data indicates a substantial inequity in PrEP use among women compared to their need. This proposed study will evaluate implementation strategies to address multi-level barriers and increase uptake of PrEP among Black cisgender women in Planned Parenthood clinics in Illinois. Our team’s preliminary work has identified successful strategies for PrEP Optimization among Women to Enhance Retention and Uptake (POWER Up). POWER Up implementation strategies address key barriers to PrEP uptake and include: 1) routine PrEP education 2) standardized provider training, 3) electronic health record (EHR) tools; and 4) PrEP navigation. These strategies have not been studied in family planning clinics with a large population of Black cisgender women. Therefore, using implementation science research methods, we propose to implement and evaluate the impact of the POWER Up strategies within the Planned Parenthood of Illinois (PPIL) health center setting to improve PrEP care continuum outcomes for Black cisgender women. By implementing POWER Up strategies in PPIL health centers we seek to address the gap in knowledge in identifying effective strategies to increase uptake of PrEP among Black cisgender women. This proposed study aims to: 1. Adapt POWER Up implementation strategies for engaging Black women in the PrEP care continuum in eight Planned Parenthood clinics in Chicago 2. Determine the effectiveness of POWER Up across eight PPIL sites within Chicago’s high prevalence HIV areas; and, 3. Assess and document implementation outcomes and report on key barriers and facilitators related to successful implementation of the intervention Findings from this study will provide insight into implementation strategies that can support effective replication across the 800 Planned Parenthood health centers and other health centers providing family planning services nationwide to reach a greater number of women at risk.