Evaluating the effectiveness of a mobile HIV prevention app to increase HIV and STI testing and PrEP initiation among rural men who have sex with men
评估移动艾滋病毒预防应用程序在农村男男性行为者中增加艾滋病毒和性传播感染检测以及 PrEP 启动的有效性
基本信息
- 批准号:10743669
- 负责人:
- 金额:$ 78.57万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-08-01 至 2028-04-30
- 项目状态:未结题
- 来源:
- 关键词:AIDS preventionAddressAffectArkansasAwarenessBehavioralBeliefBisexualCaringCellular PhoneCenters for Disease Control and Prevention (U.S.)CommunitiesConsensusCoupledDataDiagnosisDiagnostic Reagent KitsDiscriminationEffectivenessEffectiveness of InterventionsEnvironmentEpidemicEthnic OriginFaceFocus GroupsFrequenciesFundingFutureGaysHIVHIV diagnosisHIV/STDHealthHealth PersonnelHealth Services AccessibilityHomeHuman immunodeficiency virus testHybridsIncidenceInterventionInterviewKnowledgeLeadershipMaintenanceMeasuresMethodsMinorityOutcomeOwnershipParticipantPolicy MakerPopulationPrevalencePrevention programPreventive serviceProviderRaceRandomized, Controlled TrialsReach, Effectiveness, Adoption, Implementation, and MaintenanceReportingRisk AssessmentRuralSTI preventionSelf AdministrationSelf EfficacySocial EnvironmentStigmatizationSurveysTestingTransportationUnited StatesUrban PopulationWorkarmcommunity organizationscultural competencedata accessdesigneffective interventioneffectiveness evaluationeffectiveness outcomeeffectiveness-implementation RCTeffectiveness/implementation hybrideffectiveness/implementation trialefficacy testingexperiencefollow-upfuture implementationhealth care settingsimplementation evaluationimplementation outcomesimplementation strategyimplementation/effectivenessimprovedimproved outcomeinterestmHealthmenmen of colormen who have sex with menmobile applicationmotivational enhancement therapypre-exposure prophylaxispreventprevention servicepreventive interventionrural Americansrural areaself testingsexual identitysocial health determinantssocial stigmastandard of caretelehealthtesting uptaketransmission processtrial designuptakewillingness
项目摘要
Abstract
Uptake of HIV and STI testing among gay and bisexual men who have sex with men (GBMSM) in the rural
southern US is low. However, HIV and STI testing is a fundamental gateway to preventive services, such as
pre-exposure prophylaxis (PrEP), and treatment provision. Thus, it is critical that we identify methods to
increase uptake of HIV and STI testing among this population that experiences disproportionate HIV and STI
incidence. We have developed an app, Combine, that is an adaptation of HealthMindr, an app that has
demonstrated efficacy in increasing uptake of HIV testing among urban GBMSM. Combine was adapted using
input from GBMSM in rural areas to address issues specific to this population such as increased experiences
of stigma and reduced access to culturally competent care. We propose to conduct a Type 2 Hybrid
Effectiveness-Implementation randomized controlled trial to test the efficacy of Combine to increase uptake of
HIV and STI testing over 24 months of follow-up and to examine the effect of different implementation
strategies among GBMSM in the rural South. Combine will include components for self-administered risk
assessments, developing and supporting a plan for frequent HIV and STI testing, information about PrEP, and
PrEP and HIV/STI testing provider locators. Previous trials of app-based HIV prevention have included the
ability to order free HIV and STI self-test kits. However, there is not a consensus among health officials around
whether at-home self-tests are an optimal solution for increasing HIV and STI testing. Additionally, despite the
availability of free HIV and STI self-test kits in previous studies, large proportions of men still do not complete
HIV tests and even fewer complete STI tests. Thus, we will evaluate the effect of two different intervention
components on HIV and STI uptake in a 2x2 factorial trial design: availability of HIV and STI self-test kits
ordered through the app and a motivational interview designed to enhance the existing app content, increase
self-efficacy to develop and follow through with a testing plan, and develop strategies to deal with experiences
of stigma. All participants will receive the Combine app, including a locator to identify nearby HIV and STI
testing centers. Men in the control arm (Arm 1) will not have the ability to order HIV and STI self-test kits and
will not receive a motivational interview; men in Arm 2 will not have the ability to order HIV and STI self-test kits
but will receive a motivational interview; men in Arm 3 will be able to order free HIV and STI self-test kits but
will not receive a motivational interview; and men in Arm 4 will have the ability to order HIV and STI self-test
kits and will receive a motivational interview. We will assess the main effects of the availability of HIV and STI
self-test kits and the motivational interview on HIV and STI testing uptake, PrEP initiation, and intervention
maintenance over 24 months of follow up. Our community-based partner, Engaging Arkansas Communities,
will work with us through all stages of the project to ensure that we are obtaining the necessary data to inform
future implementation.
摘要
农村男同性恋者和双性恋者接受艾滋病毒和性传播感染检测的情况
美国南部低。然而,艾滋病毒和性传播感染检测是获得预防服务的基本途径,
暴露前预防(PrEP)和提供治疗。因此,至关重要的是,我们要确定方法,
在艾滋病毒和性传播感染比例过高的人群中增加艾滋病毒和性传播感染检测
发病率。我们开发了一个应用程序,联合收割机,这是一个健康的应用程序,
在城市GBMSM中增加艾滋病毒检测的效果。联合收割机采用
农村地区GBMSM的投入,以解决这一人群的具体问题,如增加经验
耻辱和减少获得文化上合格的护理的机会。我们建议进行第二类混合行动,
灵活性-实施随机对照试验,以测试联合收割机增加
艾滋病毒和性传播感染检测24个月的随访,并检查不同实施方案的效果
在南方农村的GBMSM中实施战略。联合收割机将包括自我管理风险的组件
评估,制定和支持经常进行艾滋病毒和性传播感染检测的计划,关于PrEP的信息,
PrEP和HIV/STI检测提供者定位器。以前基于应用程序的艾滋病毒预防试验包括
能够订购免费的艾滋病毒和性传播感染自我检测试剂盒。然而,卫生官员之间并没有达成共识,
家庭自我检测是否是增加艾滋病毒和性传播感染检测的最佳解决方案。此外,尽管
尽管在以前的研究中提供了免费的艾滋病毒和性传播感染自我检测包,但大部分男子仍然没有完成
艾滋病毒检测和更少的完整性传播感染检测。因此,我们将评估两种不同干预措施的效果
2x2析因试验设计中关于艾滋病毒和性传播感染感染的组成部分:艾滋病毒和性传播感染自测试剂盒的可用性
通过应用程序订购,并进行旨在增强现有应用程序内容的激励性面试,
自我效能,以制定和贯彻测试计划,并制定策略来处理经验
的耻辱。所有参与者都将收到联合收割机应用程序,包括一个定位器,以识别附近的艾滋病毒和性传播感染
测试中心对照组(第1组)的男性将无法订购艾滋病毒和性传播感染自我检测试剂盒,
将不会接受动机性访谈;第2组中的男性将无法订购艾滋病毒和性传播感染自测试剂盒
但将接受一次激励性面试;第3组的男性将能够订购免费的艾滋病毒和性传播感染自我检测试剂盒,
将不会接受动机访谈;第4组的男性将能够进行艾滋病毒和性传播感染自我检测
并将接受一次激励性面试。我们将评估艾滋病毒和性传播感染的主要影响
自我检测试剂盒和关于艾滋病毒和性传播感染检测吸收、PrEP启动和干预的动机性访谈
24个月的随访。我们以社区为基础的合作伙伴,参与阿肯色州社区,
我将在项目的所有阶段与我们合作,以确保我们获得必要的数据,
未来的实施。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Jeb Jones其他文献
Jeb Jones的其他文献
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{{ truncateString('Jeb Jones', 18)}}的其他基金
Assessing Psychosocial Predictors of PrEP Adherence and Persistence Among Young Black MSM
评估年轻黑人 MSM 中 PrEP 依从性和持久性的社会心理预测因素
- 批准号:
10452231 - 财政年份:2021
- 资助金额:
$ 78.57万 - 项目类别:
Adapting a mobile HIV prevention app to increase uptake of HIV and STI testing among rural men who have sex with men
改造移动艾滋病毒预防应用程序,以提高农村男男性行为者对艾滋病毒和性传播感染检测的接受度
- 批准号:
10213963 - 财政年份:2020
- 资助金额:
$ 78.57万 - 项目类别:
Assessing Psychosocial Predictors of PrEP Adherence and Persistence Among Young Black MSM
评估年轻黑人 MSM 中 PrEP 依从性和持久性的社会心理预测因素
- 批准号:
10010287 - 财政年份:2020
- 资助金额:
$ 78.57万 - 项目类别:
Delay Discounting and HIV Sexual Risk Behavior in Men who Have Sex with Men
男男性行为者的延迟折扣和艾滋病毒性危险行为
- 批准号:
9138001 - 财政年份:2016
- 资助金额:
$ 78.57万 - 项目类别:
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