Advanced anti-cancer activities with therapeutic agents that induce tumor cell apoptosis and antitumor immune responses.

使用诱导肿瘤细胞凋亡和抗肿瘤免疫反应的治疗剂进行先进的抗癌活性。

• 批准号: nhmrc : 550303
• 负责人: Dr Alison West
• 金额: $ 5.71万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Postgraduate Scholarships
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/advanced-anti-cancer-immune-responses/115945
• 关键词: Advanced; anti; cancer; activities; therapeutic

The aim is to perform pre-clinical studies to identify new therapies for blood cancers. We will utilise three new anti-cancer agents that kill tumor cells and genetically engineered mice that develop cancer. We will determine if these three new agents kill the mouse tumor cells and activate anti-tumor immunity. The combined effect of killing blood cancer cells using new therapeutics, coupled with enhancing the anti-cancer immune response may hold the key to developing new treatments.

其目的是进行临床前研究，以确定血癌的新疗法。我们将使用三种新的抗癌药物来杀死肿瘤细胞和发展成癌症的基因工程小鼠。我们将确定这三种新药物是否会杀死小鼠肿瘤细胞并激活抗肿瘤免疫。使用新的治疗方法杀死血液癌细胞，再加上增强抗癌免疫反应的综合效果，可能是开发新疗法的关键。