NCI Research Specialist (Clinician Scientist) Award

NCI 研究专家（临床科学家）奖

• 批准号: 10566438
• 负责人: Jennifer Haunani Foster
• 金额: $ 13.72万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2028-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10566438
• 关键词: Award; Biology; Board Certification; Cancer Control; Cancer Patient; Childhood; Childhood Solid Neoplasm; Clinical; Clinical Pharmacology; Clinical Trials; Clinical Trials Network; Committee Members; Comprehensive Cancer Center; Consent; Dedications; Development; Developmental Therapeutics Program; Enrollment; Ensure; Funding; Funding Opportunities; Institution; Lead; Leadership; Malignant Childhood Neoplasm; Mentors; Mission; Monitor; Neuroblastoma; Oncologist; Oncology; Patients; Pediatric Hematologist; Pediatric Hematology; Pediatric Oncology; Pediatric Oncology Group; Performance; Productivity; Qualifying; Recurrent disease; Refractory Disease; Research; Research Personnel; Role; Scientist; Site; Solid Neoplasm; Specialist; Therapeutic Clinical Trial; Time; Toxic effect; career; clinical trial implementation; early phase clinical trial; experience; falls; high risk; innovation; interest; meetings; member; novel therapeutics; pediatric patients; phase I trial; programs

Project Abstract I am a Pediatric Hematologist-Oncologist at the Dan L. Duncan Comprehensive Cancer Center’s Pediatric Cancer Program (DLDCCC PCP), with dual board certifications in Pediatric Hematology- Oncology and Clinical Pharmacology. I have clinical and research expertise in developmental therapeutics, neuroblastoma, and other pediatric solid tumors. I am committed to a career as a clinician-scientist, serving as a national leader in the development of national clinical trials and the implementation of NCI clinical trials at my institution and contributing to NCI clinical trial networks through participation in both scientific review and monitoring committees. My clinical and research interests are focused on ushering novel therapies into early-phase clinical trials for patients with neuroblastoma and other pediatric solid tumors and mitigating toxicities associated with therapy. Within the PCP, I am the Clinical Director of the Neuroblastoma Program, Director of the Solid Tumor Program, and the Assistant Director of the Developmental Therapeutics (DVL) Program. In these roles, I lead and implement therapeutic clinical trials for pediatric patients with solid tumors and early-phase clinical trials for pediatric cancer patients with relapsed or refractory disease. In addition, I contribute to the national leadership of the NCI-funded Children’s Oncology Group (COG) and Pediatric Early Phase Clinical Trial Network (PEP-CTN) as a member of three steering committees (Cancer Control, Neuroblastoma Biology, and Neuroblastoma); a committee member for two clinical trials treating patients with high-risk neuroblastoma; Study Chair for an ongoing phase 1 trial; a member of the PEP-CTN Performance Monitoring Committee; and site PI for the PEP-CTN at my institution. Additionally, I mentor young investigators both at my institution and through the national COG mentoring program. I attend and present annually at the COGs Fall and Spring meetings. Greater than 50% of my effort is dedicated to PI responsibilities, patient consent and enrollment activities, and administrative responsibilities directly related to my COG and PEP-CTN activities.

项目摘要 我是Dan L. Duncan综合癌症中心的儿科血液学家 - 研究学家 小儿癌症计划（DLDCCC PCP），具有小儿血液学双板认证 - 肿瘤学和临床药理学。我有发展的临床和研究专家 治疗剂，神经母细胞瘤和其他儿科实体瘤。我致力于从事职业 临床科学家，担任国家临床试验发展的国家领导者 在我的机构实施NCI临床试验并为NCI临床试验做出贡献 通过参与科学审查和监测委员会的网络。我的临床 研究兴趣的重点是将新型疗法纳入早期临床试验 神经母细胞瘤和其他儿科实体瘤的患者以及与毒性相关的毒性 进行治疗。 在PCP中，我是神经母细胞瘤计划的临床主任，实体主任 肿瘤计划，以及发育治疗学（DVL）计划的助理主任。 在这些角色中，我领导并实施了针对患有固体患者的治疗临床试验 小儿癌症患者的肿瘤和早期临床试验 疾病。此外，我为NCI资助的儿童肿瘤学的国家领导层做出了贡献 组（COG）和小儿早期临床试验网络（PEP-CTN）作为三个成员 指导委员会（癌症控制，神经母细胞瘤生物学和神经母细胞瘤）；一个委员会 两项治疗高危神经母细胞瘤患者的临床试验的成员；学习椅 正在进行的第一阶段试验； PEP-CTN绩效监测委员会成员；和网站 我机构的PEP-CTN的PI。此外，我的心理年轻调查员都在我 机构和国家齿轮心理计划。我每年参加并参加 齿轮秋季和春季会议。我的努力超过50％致力于PI责任， 患者同意和入学活动以及与我的行政责任直接相关 COG和PEP-CTN活动。