LEIDOS FUNDING TO25, OPTION 2 OBSERVATIONAL STUDY

Leidos 资助 TO25，选项 2 观察性研究

• 批准号: 10935428
• 负责人: ETHAN DMITROVSKY
• 金额: $ 1308.83万
• 依托单位: LEIDOS BIOMEDICAL RESEARCH, INC.
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-28 至 2028-08-17
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10935428
• 关键词: Biology; Cause of Death; Cessation of life; Childhood; Communicable Diseases; Coronavirus; Data; Disease; Disease Progression; Emerging Communicable Diseases; Enrollment; Funding; Human; Incidence; Infectious Agent; Medical; Medical Research; Observational Study; Pathogenesis; Patient-Focused Outcomes; Protocols documentation; Publishing; Risk Factors; Therapeutic; acute infection; clinical investigation; follow-up; improved; innovation; pathogen; post-COVID-19; previous outbreak; respiratory virus; virology

Infectious diseases remain one of the leading causes of death worldwide despite innovations in medical research and the availability of new treatments. Emerging diseases include outbreaks of previously unknown diseases or known diseases where the incidence in humans has significantly increased in the past two decades. Detailed studies on emerging and re-emerging infectious agents to better understand pathogens’ biology and host pathogenesis are mostly lacking. The initial study protocol under this Task Order is to prepare for a rapid coordinated clinical investigation of acute infections of emerging and re-emerging infectious agents.

传染病仍然是全世界主要的死亡原因之一，尽管医学研究取得了创新，也出现了新的治疗方法。新出现的疾病包括以前未知的疾病或已知疾病的暴发，在过去20年中，这些疾病在人类中的发病率显著增加。关于新出现和再次出现的感染源的详细研究，以更好地了解病原体的生物学和宿主发病机制，大多缺乏。根据这一任务令，最初的研究方案是准备对新出现和再次出现的传染病病原体的急性感染进行快速协调的临床调查。