Hermanos de Luna y Sol: A community-based HIV prevention intervention

摘要 我们研究的总体目标是减少拉丁裔移民人口中与艾滋病毒相关的健康不平等现象。 我们建议确定一个以社区为基础的团体--赫尔马诺斯·德·露娜·y·索尔(HLS)的有效性 用西班牙语提供的干预措施，旨在降低拉丁裔移民中艾滋病毒的性风险，这些移民认为 男同性恋/双性恋男性或与男性发生性关系的男性(GBMSM)。这项研究被设计为一种准实验， 社区控制，以加利福尼亚州奥克兰为干预组，以伊利诺伊州芝加哥为对照。评估 将在-3个月和0个月进行，并在3个月、6个月和12个月进行随访。参与者(N=360人；每个城市n=180人) 将使用时间-地点抽样(以场地为基础的抽样，旨在减少样本偏差)进行征聘。 HLS，这项研究的核心干预，提供了几个新的特征：它专注于移民，西班牙人- 它解决了种族主义和同性恋恐惧症作为影响艾滋病毒风险的因素的问题；并使用了 以社区为中心的方法以社区参与(例如，公民参与、志愿服务)为中心 促进性健康和社区建设的手段。 这项研究将有助于确定在拉丁裔移民GBMSM中预防艾滋病毒的有效干预措施， 严重缺乏艾滋病毒预防干预措施的边缘化人群。这项研究充分利用了 为讲西班牙语的人群设计的现有干预措施；是此类干预中第一个严格测试 使用社区控制设计对拉丁裔移民GBMSM进行干预的有效性。这项研究 应用尽可能最佳的科学方法来获得干预效果的估计。如果成功，则 干预措施将相对容易通过社区组织和疾病中心传播 控制和预防。最终，这项研究将有助于推动减少种族/民族健康的努力 不平等，这是该国主要的公共卫生优先事项之一。 这项建议与解决健康差距的变革性研究直接相关 促进少数民族服务机构的卫生公平。该项目由西班牙裔服务生SFSU领导 机构--与两个拉丁裔社区组织合作：La Familia和Chicago Queer Latinx Collaborative。我们是一个多学科的研究团队，在以下方面拥有丰富的经验 与Latinx和GBMSM社区一起成功开展艾滋病毒预防研究。所有高级人员 他们都是拉丁美洲后裔，完全掌握双语(西班牙语和英语)，其中三人是女性。这个 拟议的研究与美国国立卫生研究院促进种族平等和包容的联合倡议非常一致 生物医学研究，响应多个NIH研究所和中心的优先领域，如NIMHD， NIMH和艾滋病研究办公室。

Abstract The overall goal of our research is to reduce HIV-related health inequities among Latinx immigrant populations. We propose to determine the effectiveness of Hermanos de Luna y Sol (HLS), a community-based, group intervention delivered in Spanish, designed to reduce HIV sexual risk among Latinx immigrants who identify as gay/bisexual men or men who have sex with men (GBMSM). The study is designed as a quasi-experimental, community control, with Oakland, CA as the intervention group and Chicago, IL as the control. Assessments will be conducted at -3 and 0 mos., and follow-ups at 3, 6, and 12 mos. Participants (N=360; n=180 per city) will be recruited using Time-location sampling (a venue-based sampling designed to reduce sample bias). HLS, the intervention at the heart of this study, offers several novel features: it focuses on immigrant, Spanish- speaking populations; it addresses racism and homophobia as factors shaping HIV risk; and uses a community-based approach centered on community involvement (e.g., civic participation, volunteering) as a means to foster sexual health and community building. The study will help identify effective interventions to prevent HIV among Latinx immigrant GBMSM, a marginalized population for which HIV preventive interventions are severely lacking. This study capitalizes on an existing intervention designed for Spanish speaking populations; is the first of its kind to rigorously test the intervention’s effectiveness among Latinx immigrant GBMSM using a community control design. The study applies the best possible scientific approach to obtain estimates of intervention effectiveness. If successful, the intervention would be relatively easy to disseminate via community organizations and the Centers for Disease Control and Prevention. Ultimately, the study will help move forward efforts to reduce racial/ethnic health inequities, one of the nation’s major public health priorities. This proposal is directly relevant to the RFA on Transformative Research to Address Health Disparities and Advance Health Equity at Minority serving Institutions. The project is led by SFSU – a Hispanic Serving Institution-- in collaboration with two Latinx community-based organizations: La Familia and Chicago Queer Latinx Collaborative. We are a multidisciplinary research team with the depth and breadth of experience on HIV prevention with Latinx and GBMSM communities to successfully conduct the study. All senior personnel are of Latin American descent, fully bilingual (Spanish and English), and three of them are women. The proposed study is strongly aligned with NIH UNITED Initiative of fostering racial equity and inclusion in biomedical research and is responsive to priority areas of multiple NIH institutes and centers, such NIMHD, NIMH, and the Office of AIDS Research.