Hermanos de Luna y Sol: A community-based HIV prevention intervention

摘要 我们研究的总体目标是减少拉丁裔移民人口中与艾滋病毒相关的健康不平等。 我们建议确定一个以社区为基础的团体“月亮和太阳兄弟”的有效性， 以西班牙语提供的干预措施，旨在降低拉丁裔移民中的艾滋病毒性风险， 男同性恋/双性恋或与男性发生性关系的男性（GBMSM）。这项研究被设计为准实验性的， 社区对照，以加利福尼亚州奥克兰市为干预组，以伊利诺伊州芝加哥市为对照组。评估 将在-3和0月进行，并在3、6和12个月进行随访。参与者（N=360; n=180/城市） 将使用时间-地点抽样（旨在减少样本偏倚的基于场地的抽样）招募。 HLS是这项研究的核心干预措施，它提供了几个新的特点：它侧重于移民，西班牙- 它将种族主义和仇视同性恋作为形成艾滋病毒风险的因素;并使用 以社区参与为中心的基于社区的方法（例如，公民参与，志愿服务）作为一个 促进性健康和社区建设的手段。 这项研究将有助于确定有效的干预措施，以防止艾滋病毒在拉丁裔移民GBMSM， 严重缺乏艾滋病毒预防干预措施的边缘化人口。这项研究利用了 为讲西班牙语的人群设计的现有干预措施;是第一个严格测试 使用社区控制设计在拉丁裔移民GBMSM中干预的有效性。研究 采用尽可能最好的科学方法来估计干预措施的有效性。如果成功， 通过社区组织和疾病中心， 控制和预防。最终，这项研究将有助于推动减少种族/民族健康的努力。 不公平，国家的主要公共卫生优先事项之一。 该提案与RFA关于解决健康差异的变革性研究直接相关， 促进少数民族服务机构的健康公平。该项目由SFSU领导-一个西班牙裔服务 机构-与两个拉丁裔社区组织：La Familia和芝加哥同性恋者组织合作 Latinx协作。我们是一个多学科的研究团队，拥有丰富的经验， 艾滋病毒预防与拉丁裔和GBMSM社区成功地进行了研究。所有高级人员 这些人是拉丁美洲后裔，完全双语（西班牙语和英语），其中三人是妇女。的 拟议的研究与促进种族平等和包容的NIH UNITED倡议密切一致， 生物医学研究，并响应多个NIH研究所和中心的优先领域，如NIMHD， NIMH和艾滋病研究办公室。

Abstract The overall goal of our research is to reduce HIV-related health inequities among Latinx immigrant populations. We propose to determine the effectiveness of Hermanos de Luna y Sol (HLS), a community-based, group intervention delivered in Spanish, designed to reduce HIV sexual risk among Latinx immigrants who identify as gay/bisexual men or men who have sex with men (GBMSM). The study is designed as a quasi-experimental, community control, with Oakland, CA as the intervention group and Chicago, IL as the control. Assessments will be conducted at -3 and 0 mos., and follow-ups at 3, 6, and 12 mos. Participants (N=360; n=180 per city) will be recruited using Time-location sampling (a venue-based sampling designed to reduce sample bias). HLS, the intervention at the heart of this study, offers several novel features: it focuses on immigrant, Spanish- speaking populations; it addresses racism and homophobia as factors shaping HIV risk; and uses a community-based approach centered on community involvement (e.g., civic participation, volunteering) as a means to foster sexual health and community building. The study will help identify effective interventions to prevent HIV among Latinx immigrant GBMSM, a marginalized population for which HIV preventive interventions are severely lacking. This study capitalizes on an existing intervention designed for Spanish speaking populations; is the first of its kind to rigorously test the intervention’s effectiveness among Latinx immigrant GBMSM using a community control design. The study applies the best possible scientific approach to obtain estimates of intervention effectiveness. If successful, the intervention would be relatively easy to disseminate via community organizations and the Centers for Disease Control and Prevention. Ultimately, the study will help move forward efforts to reduce racial/ethnic health inequities, one of the nation’s major public health priorities. This proposal is directly relevant to the RFA on Transformative Research to Address Health Disparities and Advance Health Equity at Minority serving Institutions. The project is led by SFSU – a Hispanic Serving Institution-- in collaboration with two Latinx community-based organizations: La Familia and Chicago Queer Latinx Collaborative. We are a multidisciplinary research team with the depth and breadth of experience on HIV prevention with Latinx and GBMSM communities to successfully conduct the study. All senior personnel are of Latin American descent, fully bilingual (Spanish and English), and three of them are women. The proposed study is strongly aligned with NIH UNITED Initiative of fostering racial equity and inclusion in biomedical research and is responsive to priority areas of multiple NIH institutes and centers, such NIMHD, NIMH, and the Office of AIDS Research.