Medical Scientist Training Program

医学科学家培训计划

• 批准号: 10625664
• 负责人: Myles H. Akabas
• 金额: $ 185.77万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10625664
• 关键词: Medical; Scientist; Training Programs

PROJECT SUMMARY The mission of the Albert Einstein College of Medicine Medical Scientist Training Program (MSTP) is to train physician-scientists who will become leaders in biomedical research to understand, detect, treat, and prevent human disease. To accomplish this mission, we have three goals, 1) to recruit a diverse group of students with outstanding potential to become research-active physician-scientists, 2) to provide training in an inclusive, safe, and stimulating learning environment where students can acquire the foundational knowledge and the technical, operational, and professional skills necessary to pursue a career as a research-active physician- scientist and a leader in academic medicine and/or biomedical research, and 3) to support/facilitate their professional development to transition to the next stage in the training continuum. Through a holistic admissions process, we seek to identify individuals with the intelligence, curiosity, creativity, resilience, perseverence, and enthusiam for science that is essential for a successful research career. We guide the students through a program tailored to meet their individual needs and interests. The program provides rigorous, integrated medical and research training through a flexible, continously evolving curriculum that includes 1) specialized MSTP courses, and 2) integration of graduate and medical school curriculum in the first 2 years and throughout the program. The training program has 3 phases. In the first 2 years students take a combination of medical, graduate, and MSTP-specific courses to gain the didactic foundation for their reseach and clinical training. Research rotations and guidance from program leadership assist them in thesis lab selection. In the program’s 2nd phase, students perform independent, original research under their mentor’s guidance. They publish their discoveries in high quality, peer-reviewed papers, and prepare and defend a PhD thesis. Participation in a PhD phase MSTP-run, outpatient clinic builds clinical skills. In the final phase, they complete their clinical training. A multifaceted approach trains students to perform rigorous and reproducible research in a responsible, ethical manner. Currently, the program has 113 trainees, 41% woman, 28% from groups underrepresented in medicine (twice percentage in the applicant pool), and 11% with disabilities. We will expand to ~120-130 trainees by increasing the entering class size to 16. Since its inception in 1964, as one of the first three NIH-funded MSTPs, 484 trainees have graduated. 413 have completed postgraduate training and published over 19,000 papers, an average of ~47 papers/graduate. 74% have jobs at academic medical centers, research institutes, NIH or pharmaceutical companies. By various measures, the graduates have achieved outstanding success and advanced biomedical research and academic medicine. We propose to further integrate graduate and medical training, and increase opportunities for involvement in clinical and translational research to prepare a future generation of physician-scientists who will be at the leading edge of biomedical research with the ultimate goal of improving human health and reducing the burden of disease.

项目摘要 阿尔伯特·爱因斯坦医学院医学科学家培训计划（MSTP）的使命是培训 医学科学家，他们将成为生物医学研究的领导者，以了解，检测，治疗和预防 人类疾病。为了完成这一使命，我们有三个目标，1）招募一个多样化的学生群体， 成为研究活跃的医生科学家的杰出潜力，2）提供包容性的培训， 安全，刺激的学习环境，学生可以获得基础知识和 技术，操作和专业技能，追求职业生涯作为一个研究活跃的医生- 科学家和学术医学和/或生物医学研究的领导者，以及3）支持/促进他们的 专业发展过渡到下一阶段的培训连续性。通过整体 招生过程中，我们寻求识别个人的智力，好奇心，创造力，弹性， 坚持不懈，对科学的热情，这是一个成功的研究生涯所必需的。我们引导 学生通过一个程序量身定制，以满足他们的个人需求和兴趣。该计划提供 通过灵活的，不断发展的课程，严格的，综合的医学和研究培训， 包括1）专门的MSTP课程，2）第一阶段研究生和医学院课程的整合 2年，贯穿整个计划。培训计划有三个阶段。在前两年，学生需要一个 医学，研究生和MSTP特定课程的组合，以获得他们的研究教学基础 临床培训。项目领导的研究轮换和指导帮助他们在论文实验室工作 选择.在该计划的第二阶段，学生在导师的指导下进行独立的原创性研究。 指导他们在高质量的同行评议论文中发表他们的发现，并准备和捍卫博士学位 论文参加博士阶段MSTP运行，门诊诊所建立临床技能。在最后阶段，他们 完成临床培训。一个多方面的方法训练学生执行严格和可重复的 以负责任、合乎道德的方式进行研究。目前，该方案有113名受训人员，41%为妇女，28%来自 在医学领域代表性不足的群体（在申请人中的比例是申请人的两倍）和11%的残疾人。我们 将扩大到约120-130名学员，增加入班人数至16人。自1964年成立以来，作为 在国家卫生研究所资助的前三个MSTPs中，有484名学员毕业。413人完成研究生培训 发表论文19,000余篇，平均每毕业生发表论文47篇。74%的人在学术医疗机构工作 中心、研究机构、NIH或制药公司。通过各种措施，毕业生 取得了杰出的成就和先进的生物医学研究和学术医学。我们建议 进一步整合研究生和医学培训，增加参与临床和 转化研究，以准备未来一代的医生，科学家谁将处于领先地位， 生物医学研究的最终目标是改善人类健康和减轻疾病负担。