National Pediatric Rehabilitation Resource Center: Pilot Studies

项目概要（试点研究） 我们建议赞助一项试点研究计划，作为对研究者参与的一个非常有吸引力的激励措施。 国家儿科康复资源中心（PedRehab Ctr）试点研究计划将把高 优先鼓励创新和资助试点研究， 治疗和促进其快速，高保真，有效地应用到临床和社区环境 （执行科学）。我们还将考虑在试点项目下进行方法和技术开发研究 研究计划，特别是当主题填补了一个关键的差距或寻求克服一个重大障碍， 对儿科人群进行高质量的医疗康复研究。我们将尽最大努力 允许的金额（每年$150，000 × 5年=$750，000）。我们提议与美国人合作 脑瘫和发育医学学院（AACPDM）协助宣布，审查， 根据其目前的战略计划，对试点研究进行评分，这是一个强有力的同行审查和跟踪试点研究的过程。 研究成果，以及它在与NIH密切合作，建立和促进新的共同 脑瘫的治疗方法最终的资金决定将由PedRehab Ctr团队根据输入做出 并获得独立的国家咨询委员会的批准。 我们的试点研究的具体目标是：1）协同工作，鼓励发展高度 有前途的想法和方法，将受益于急需的试点研究数据，以获得更大的 规模NIH资金; 2）为研究人员和跨学科研究团队提供直接援助，因为他们计划 三）及时拨款资助最有价值的申请;四） 提供获奖后的直接援助（包括我们PedRehab Ctr内的活动， 机会和技术开发），以最大限度地提高 成功完成并随后使用成果;以及5）监测试点项目产生的科学成果 研究以及如何在随后的研究活动中使用。与AACPDM合作，我们将收集 接受者关于试点研究计划影响的评估数据。总的来说，我们的试点项目 研究计划包括嵌入式辅导和协作-从提交前到获奖后。

Project Summary (Pilot Studies) We propose to sponsor a Pilot Studies program as a highly attractive incentive for investigators to engage with our National Pediatric Rehabilitation Resource Center (PedRehab Ctr). The Pilot Studies program will place high priority on encouraging innovation and funding pilot studies with high potential for discovering efficacious treatments and promoting their rapid, high-fidelity, and effective application into clinical and community settings (Implementation Science). We also will consider methods and techniques development research under the Pilot Studies program, particularly when the topic fills a critical gap or seeks to overcome a major obstacle to conducting high-quality medical rehabilitation research with pediatric populations. We will invest the maximum amount allowed ($150,000 per year X 5 years = $750,000). We have proposed a partnership with the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) to assist in announcing, reviewing, and scoring the Pilot Studies, based on its current strategic plan, a strong process of peer review and tracking of pilot study outcomes, and its role in working closely with NIH to establish and promote the use of the new Common Data Elements for Cerebral Palsy. Final funding decisions will be made by the PedRehab Ctr team with input and approval from the independent National Advisory Board. Our specific aims for Pilot Studies are: 1) to work collaboratively to encourage the development of highly promising ideas and methods that will benefit from critically needed Pilot Study data in order to obtain larger scale NIH funding; 2) to offer direct assistance to investigators and interdisciplinary research teams as they plan and finalize their proposals; 3) to provide timely funding for those applications judged the most meritorious; 4) to lend post-award direct assistance (including activities within our PedRehab Ctr for Mentored Collaborative Opportunities and Techniques Development) to those who receive funding with the goal of maximizing successful completion and later use of results; and 5) to monitor the scientific findings generated by the Pilot Studies and how these are used in subsequent research activities. In partnership with AACPDM, we will collect evaluative data from the recipients about the impact of the Pilot Studies program. Overall, our proposed Pilot Studies program includes embedded mentoring and collaboration – from pre-submission through post-award.