Integrative Training in the Neurobiology of Addictive Behaviors

项目总结/摘要 芝加哥大学成瘾行为神经生物学项目的综合训练 为博士前和博士后学员提供药物滥用相关研究方面的培训。我们的核心教师培训师 是有着成功培训证书的高效研究人员。他们的专长包括分子生物学， 电生理学、药理学和药物成瘾的动物模型，对社会、行为和 人类药物使用的精神药理学方面，包括病因学，治疗和药物政策。定量 强调方法和可重复性。我们的目标是培养下一代科学家， 采用综合方法探讨药物滥用的病因、预防和治疗。 我们提出了3个博士前和4个博士后实习生的计划。学员将得到 培训计划为1-3年（通常为2年）。学员在“家中”接受专门的强化培训 实验室，但他们也接触到自己领域以外的成瘾研究的全方位。到 确保学员之间以及学员与培训师之间有实质性的互动，我们 安排两周一次的会议，包括期刊俱乐部的演讲和邀请演讲者的研讨会。 教学课程范围从分子细胞神经科学到系统和行为神经科学， 从统计学到计算神经科学和生物信息学，从遗传学和流行病学到治疗和 政策我们的T32增强培训经验的另一个机制是“实习”计划， 我们的学员在实验室或与他们自己不同的环境中接受指导。的 组织结构包括一个执行委员会作出全面的培训决策， 委员会确保受训人员的良好流动和平衡，计划和审查委员会监督 学员的进步，以及一个外部咨询委员会，提供专家外部咨询。 芝加哥大学提供了一个独特的环境，既有悠久的跨学科历史， 合作，最近对神经科学研究的重大承诺。这提供了丰富的知识分子 在药物滥用相关研究中为受训人员提供背景。除了T32支持的学员外，我们还 增加了准会员，以便任何对成瘾研究感兴趣的学员都可以参加任何 T32赞助活动。这使我们能够汇集来自校园的其他学员和教师， 提高对成瘾研究及其与其他学科相关性的认识。它带来了新的专业知识 并大大丰富了培训机会。我们将投入资源招募 代表性不足的少数民族，我们将提供全面的研究道德行为培训。

PROJECT SUMMARY/ABSTRACT The Integrative Training in the Neurobiology of Addictive Behaviors Program at The University of Chicago offers training for both pre- and postdoctoral trainees in drug abuse-related research. Our core faculty trainers are productive researchers with successful training credentials. Their expertise ranges from molecular biology, electrophysiology, pharmacology and animal models of drug addiction, to the social, behavioral and psychopharmacological aspects of human drug use, including etiology, treatment and drug policy. Quantitative approaches and reproducibility are emphasized. Our goal is to prepare the next generation of scientists to investigate the etiology, prevention and treatment of drug abuse with integrative approaches. We propose a program for 3 predoctoral and 4 postdoctoral trainees. Trainees will be supported by the Training Program for 1-3 years (usually 2 years). Trainees obtain specialized intensive training in their ‘home’ laboratories, but they are also exposed to the full breadth of addictions research outside their own area. To ensure that there is substantial interaction among the trainees, and between trainees and trainers, we schedule bi-weekly meetings consisting of journal club presentations and seminars by invited speakers. Didactic courses range from molecular cellular neuroscience to systems and behavioral neuroscience, from statistics to computational neuroscience and bioinformatics, from genetics and epidemiology to treatment and policy. One other mechanism by which our T32 has enhanced training experience is the “externship” program, in which our trainees receive mentored experiences in laboratories or settings removed from their own. The organizational structure includes an Executive Committee making overall training decisions, a Selection Committee to ensure a good flow and balance of trainees, a Program and Review Committee to monitor trainees’ progress, and an External Advisory Committee to provide expert outside consultation. The University of Chicago provides a unique environment with both a long history of interdisciplinary collaboration and recently a significant commitment to neuroscience research. This provides a rich intellectual context for trainees in drug abuse related research. In addition to the trainees supported by the T32, we have added Associate Members so that any trainee who is interested in addiction research can participate in any of the T32 sponsored activities. This allows us to bring together other trainees and faculty from across campus to raise consciousness about addiction research and its relevance to other disciplines. It brings in new expertise to the group and significantly enriches training opportunities. We will devote resources to recruiting underrepresented minorities and we will provide comprehensive training in ethical conduct of research.