Obesity & Gastrointestinal Surgery Research Training Program

项目摘要 概述：肥胖和胃肠道疾病是最常见的手术适应症之一（例如， 减肥手术、胃食管反流、疝气、憩室炎等）。然而， 与其他临床领域相比研究这些主题的科学家（例如，肿瘤外科，血管外科， 移植），特别是外科医生科学家。这项T32补助金，“肥胖和胃肠外科” 科学家培训计划”将整合肥胖和胃肠道手术研究的各个方面， 密歇根大学-从“板凳旁边，实践政策”-使我们能够解决基本的 以多学科方式提出问题1 -7。该计划将通过整合这些不同的外科研究来改善外科研究。 在科学家、临床医生和卫生服务部门之间产生重大交叉影响的科学学科 调查人员对这一关键问题的看法。加强培训将增加使用的外科调查员数量 复杂的方法来解决这些大规模的问题与手术方法来治疗肥胖和 胃肠道疾病密歇根大学是在一个独特的位置进行博士后T32 肥胖和胃肠外科培训计划，包括基础机械科学和 临床结果研究。除了我们在肥胖、代谢和结果方面的现有优势之外 研究，这项工作的大部分领导兰迪塞利，博士，我们相信密歇根大学有一个 前所未有的科学家的临界质量集中在肥胖与胃肠手术的交叉点。 此外，密歇根大学是一个国家中心的卓越的手术结果和卫生服务 由NIH，AHRQ和PCORI资助的强大工作概况的研究。贾斯汀B。迪米克，医学博士，公共卫生硕士，主席 外科系，领导这一卓越领域，其中包括医疗保健成果中心和 政策，密歇根减肥手术协作（MBSC）和密歇根手术质量协作 （MSQC），全州临床数据登记和质量改进计划，重点是肥胖和胃肠道 手术，分别。有许多科学的培训计划，重点是研究肥胖和 胃肠道疾病然而，没有专门用于培养科学家和 外科医生-科学家，致力于研究肥胖手术和胃肠手术， 这两个重要疾病领域的交叉点。尽管这项提议将培养外科医生和科学家 和非外科医生科学家（即，博士和非外科临床科学家），迫切需要更多 科学家在这些领域。重要的是要有科学训练的外科医生谁可以问重要的 提出问题，进行有意义的研究。具体来说，更多的肥胖和胃肠外科科学家 需要：提供更多的智力马力和研究创造力;提供专业- 具体的临床专业知识，以指导研究;建立思想领袖谁可以最终影响改变内 手术

PROJECT SUMMARY ABSTRACT Overview: Obesity and gastrointestinal diseases are among the most common indications for surgery (e.g., bariatric surgery, gastroesophageal reflux, hernias, diverticulitis, etc…). However, there are considerably fewer scientists studying these topics compared to other clinical areas (e.g., surgical oncology, vascular surgery, transplantation), particularly among surgeon-scientists. This T32 grant, “Obesity & Gastrointestinal Surgery Scientist Training Program” will integrate all aspects of obesity and gastrointestinal surgery research at the University of Michigan – from “bench to beside, and practice to policy”— allowing us to address fundamental questions in a multidisciplinary way1–7. This program will improve surgical research by integrating these various scientific disciplines to produce significant cross-fertilization among scientists, clinicians, and health service investigators on this critical topic. Enhanced training will increase the number of surgical investigators using sophisticated approaches to these large-scale problems associated with surgical approaches to treat obesity and gastrointestinal diseases. The University of Michigan is in a unique position to conduct post-doctoral T32 training program in obesity & gastrointestinal surgery that includes both basic mechanistic science and clinical outcomes research. In additional to our existing strengths in obesity, metabolism, and outcomes research, much of this work led by Randy Seeley, PhD, we believe the University of Michigan has an unprecedented critical mass of scientists focusing on the intersection of obesity with gastrointestinal surgery. Moreover, the University of Michigan is a national center of excellence in surgical outcomes and health services research with a robust profile of work funded by NIH, AHRQ and PCORI. Justin B. Dimick, MD, MPH, the chair of the Department of Surgery, leads this area of excellence, which includes the Center for Healthcare Outcomes & Policy, the Michigan Bariatric Surgery Collaborative (MBSC), and the Michigan Surgical Quality Collaborative (MSQC), statewide clinical data registry and quality improvement programs focused on obesity and gastrointestinal surgery, respectively. There are numerous scientific training programs that focus on research on obesity and gastrointestinal diseases. However, there are no programs specifically dedicated to preparing scientists and surgeon-scientists for a career dedicated to studying surgery for obesity and gastrointestinal surgery, and the intersection of these two important disease areas. Although this proposal will train both surgeon- scientists and non-surgeon scientists (i.e., PhDs and non-surgery clinician scientists), there is an acute need for more surgeon scientists in these fields. It is important to have scientifically trained surgeons who can ask important questions and conduct meaningful research. Specifically, more obesity & gastrointestinal surgery scientists are needed for the following: Provide more intellectual horsepower and research creativity; Provide the specialty- specific clinical expertise to steer research; To establish thought leaders who can ultimately effect change within surgery.