Novel strategies to improve stroke outcome

改善中风结果的新策略

• 批准号: nhmrc : GNT1160693
• 负责人: Dr Connie Wong
• 金额: $ 48.34万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-strategies-improve-stroke-outcome/1349321
• 关键词: Novel; strategies; improve; stroke; outcome

Infection is a common and fatal complication of stroke. With the escalating problem of antibiotic-resistance, new therapeutic approaches are urgently needed. Research from my laboratory shows that stroke not only damages the brain, but also weakens host antibacterial defence. I will use innovative methods to identify signalling pathways that underlie immune dysfunction. The results will allow us to develop novel strategies for strengthening host immunity and improve stroke outcomes.

感染是中风的常见和致命的并发症。随着抗生素耐药性问题的日益严重，迫切需要新的治疗方法。我实验室的研究表明，中风不仅会损害大脑，还会削弱宿主的抗菌防御。我将使用创新的方法来识别免疫功能障碍的信号通路。这些结果将使我们能够开发新的策略来增强宿主免疫力和改善中风的结果。