Novel surgery-chemotherapy-immunotherapy approaches for lung malignancies

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Many patients undergo cancer surgery every year yet still die of cancer over the next few years because the surgeon couldnt remove all of the cancer cells, many of which were undetectable at the time of surgery. This grant will develop ways of combining chemotherapy drugs with immune therapy to 'mop up' hidden residual cancer cells after operations - the immune system, when stimulated appropriately, should be able to 'seek and destroy' those hidden deposits and thus cure these cancers.