Novel surgery-chemotherapy-immunotherapy approaches for lung malignancies

肺部恶性肿瘤的手术-化疗-免疫治疗新方法

• 批准号: nhmrc : 1050938
• 负责人: A/Pr John Alvarez
• 金额: $ 44.2万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-surgery-chemotherapy-lung-malignancies/112187
• 关键词: Novel; surgery; chemotherapy; immunotherapy; approaches

Many patients undergo cancer surgery every year yet still die of cancer over the next few years because the surgeon couldnt remove all of the cancer cells, many of which were undetectable at the time of surgery. This grant will develop ways of combining chemotherapy drugs with immune therapy to 'mop up' hidden residual cancer cells after operations - the immune system, when stimulated appropriately, should be able to 'seek and destroy' those hidden deposits and thus cure these cancers.

每年都有许多病人接受癌症手术，但在接下来的几年里仍然死于癌症，因为外科医生无法切除所有的癌细胞，其中许多在手术时是无法检测到的。这项拨款将开发将化疗药物与免疫治疗相结合的方法，以“扫荡”手术后隐藏的残留癌细胞-免疫系统，当受到适当刺激时，应该能够“寻找并摧毁”这些隐藏的沉积物，从而治愈这些癌症。