The scientific basis for the integration of surgery and immunotherapy for lung malignancies

肺恶性肿瘤手术与免疫治疗相结合的科学依据

• 批准号: nhmrc : 572669
• 负责人: A/Pr John Alvarez
• 金额: $ 34.43万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/scientific-basis-integration-lung-malignancies/99477
• 关键词: scientific; basis; integration; surgery; immunotherapy

The work in this grant focuses on the effects of cancer surgery (tumor resection and removal of lymph nodes) on the anti-cancer immune response. It also examines whether delivery of agents into the residual tumour bed following surgery can effectively boost the effects of surgery on the immune system. The results obtained will help guide the rational design of future combination surgery-immunotherapy treatment regimens.

这项资助的工作重点是癌症手术（肿瘤切除和淋巴结切除）对抗癌免疫反应的影响。它还检查了手术后将药物输送到残留的肿瘤床中是否可以有效地增强手术对免疫系统的影响。研究结果将有助于指导未来手术-免疫治疗联合治疗方案的合理设计。