Center for Population Health Research

项目摘要/摘要 众所周知，农村人口，特别是农村儿童，不成比例地遭受着几种 对生活质量产生不利影响的慢性病和风险因素。例如，乡村与 婴儿死亡率较高，婴儿下呼吸道感染住院率增加， 儿童早期接种可预防疾病的疫苗接种率较低。资源与研究 以农村卫生为目标的主要重点是解决获得医疗服务和 但改善农村儿童的整体健康和降低风险也需要 更全面地了解如何制定、适应和测试预防策略 在农村社区。我们的总体目标是建立一个可持续发展的预防研究中心(CPR)。这个 CPR旨在支持研究人员跨越预防研究连续体，从国家 最先进的流行病学和模型CPR项目到R01资助的干预研究，这是知情和 通过CPR支持开发。几个关键障碍限制了发展以农村为导向的中心的潜力 侧重于儿童健康的预防研究，包括(1)电子健康记录的有限获取； (2)主要面向城市环境的建模资源和方法；(3)基于证据的 主要为城市社区开发并在其中进行测试的干预策略，但很少 根据农村利益相关者的意见设计的解决方案；以及(4)建立 一大批具有科学竞争力的调查人员。CPR是专门为解决这些问题而设计的 并将通过三个具体目标实现其总体目标。首先，CPR将支持、发展和 扩大蒙大拿州解决农村儿童健康问题的研究人员的关键群体。行政部门 CORE将通过各种机制积极招募新的预防研究人员到CPR，包括 新的招聘、试点项目以及与蒙大拿州其他校区的合作。第二，心肺复苏将建立 为中心调查人员提供最先进的技术工具和专业知识的研究核心 预防干预战略的流行病学和模型化以及向制定和测试的过渡 儿童健康。数据和建模核心将为CPR研究人员提供集中的资源， 拥有最先进的数据采集和敏感数据管理；生物统计和建模 专业知识；以及高性能计算资源。利益相关者的参与和干预 Support Core将为CPR研究人员提供调查和定性方法支持，以向农村和 利益相关者知情干预第三，也是最终，CPR将创造一种可持续的以中心为基础的文化 这通过辅导促进了围绕农村儿童健康预防研究的多学科成功， 合作交流和支持学术生产力和成果。

Project Summary/Abstract It is well understood that rural populations, especially rural children, suffer disproportionately from several chronic diseases and risk factors that adversely impact quality of life. For example, rurality is associated with higher infant mortality, increased rates of lower respiratory tract infection hospitalization among infants and young children and lower rates of early childhood vaccinations for preventable disease. Resources and studies targeting rural heath have primarily focused on addressing problems of access to healthcare services and healthcare professionals, but improving overall health and reducing risks among rural children also requires a more comprehensive understanding of how prevention strategies can be developed for, adapted to, and tested in rural communities. Our overall goal is to build a sustainable Center for Prevention Research (CPR). The CPR is designed to support researchers in advancing across the prevention research continuum from state-of- the-art epidemiological and modeling CPR projects to R01-funded intervention research that is informed and developed through CPR support. Several key barriers limit the potential for developing a rural-oriented center focused on prevention research for children’s health, including (1) limited access to electronic health records; (2) modeling resources and methods that are primarily oriented to urban settings; (3) evidenced based intervention strategies that have been primarily developed for, and tested within, urban communities but few solutions that have been designed with input from rural-based stakeholders; and (4) challenges to establishing a critical mass of scientifically competitive investigators. The CPR is specifically designed to address these barriers and will achieve its overall goal through three specific aims. First, CPR will support, develop and expand a critical mass of researchers in Montana addressing rural children’s health issues. The Administrative Core will actively recruit new prevention researchers to the CPR through a variety of mechanisms including new hires, pilot projects and collaborations with other Montana campuses. Second, CPR will establish research cores that provide Center investigators with state-of-the-art technical tools and expertise to conduct epidemiological and modeling and transition to development and testing of intervention strategies to protect children’s health. The Data and Modeling Core will provide CPR researchers with a centralized resource that houses state-of-the-art data acquisition and management of sensitive data; biostatistics and modeling expertise; and high performance computational resources. The Stakeholder Engagement and Intervention Support Core will provide CPR researchers with survey and qualitative methods support to inform rural and stakeholder informed interventions Third, and ultimately, CPR will create a sustainable Center-based culture that fosters multidisciplinary success around prevention research for rural children’s health through mentoring, collaborative exchange and support for scholarly productivity and achievement.