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中文摘要
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描述(由申请人提供):第三届分枝杆菌年会将于2009年11月在路易斯安那州卡维尔一个历史悠久的前麻风病疗养院举行。这次会议是由米歇尔·拉森(阿尔伯特·爱因斯坦医学院)和雷·沃特斯(美国农业部国家动物疾病中心)与克里斯汀·西泽莫尔(NIAID)共同组织的。会议系列的目的是将研究分枝杆菌疾病/宿主的基础研究人员、临床医生和兽医研究人员聚集在一起。第一次会议于2007年9月在爱荷华州艾姆斯的国家动物疾病中心举行,第二次会议于2008年9月在宾夕法尼亚州葛底斯堡举行。这些会议规模较小(约70-80人),并开放注册。会议采用研讨会形式,以促进公开和互动的讨论。13个模型(小鼠、豚鼠、棉鼠、兔子、獾、负鼠、螳螂、鱼、鹿、牛、大象、猴子和人)以及实验和自然感染(牛分枝杆菌和结核分枝杆菌引起的结核病;麻风分枝杆菌引起的麻风病,副结核分枝杆菌引起的Johnes病,以及溃疡分枝杆菌和非结核分枝杆菌引起的一般分枝杆菌感染)都纳入了不同的观点。爱荷华州会议的重点是这些模型在理解肌肉细菌疾病、发病机制和疫苗开发方面的实用性和局限性。葛底斯堡会议的重点是免疫病理学,卡维尔会议的主题将是比较分枝杆菌学。我们的目标是让年轻的研究人员作为这些会议的演讲者和主持人,以促进对新想法的讨论,并允许发展通常不相互作用的研究小组之间的合作。
英文摘要
DESCRIPTION (provided by applicant): The 3rd annual Many Hosts of Mycobacteria meeting will be held at a historic former leprosy sanatorium in Carville, Louisiana in November 2009. This meeting is co-organized by Michelle Larsen (Albert Einstein College of Medicine) and Ray Waters (National Animal Disease Center, USDA) in consultation with Christine Sizemore (NIAID). The purpose of the meeting series is to bring together basic researchers, clinicians, and veterinary medicine researchers that study mycobacterial diseases/hosts. The first meeting in September 2007 was held at the National Animal Disease Center in Ames, Iowa and the second meeting was held in September 2008 in Gettysburg, Pennsylvania. These meetings are small (~70-80 attendees) and have open registration. A workshop format is used for the meetings to foster open and interactive discussion. The diverse perspectives are exemplified by inclusion of thirteen models (mouse, guinea pig, cotton rat, rabbit, badger, possum, armadillo, fish, deer, cattle, elephant, monkeys and humans) and both experimental and natural infections (Tuberculosis from M. bovis and M. tuberculosis; Leprosy from M. leprae, Johnes Disease from M. avium paratuberculosis, and general mycobacterial infections from M. ulcerans and non-tuberculous mycobacteria). The focus of the Iowa meeting was on the utility and limitations of these models in understanding myobacterial disease, pathogenesis, and vaccine development. The Gettysburg meeting focused on immunopathology, and the theme of the Carville meeting will be on comparative mycobacteriology. We target inclusion of young investigators as speakers and moderators for these meetings to foster discussion of new ideas and allow for development of collaboration between research groups that do not typically interact with each other.
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Advanced Genotypic and Phenotypic monitoring of Drug Resistant TB to Improve TB Treatment Outcomes
Advanced Genotypic and Phenotypic monitoring of Drug Resistant TB to Improve TB Treatment Outcomes
Many Hosts of Mycobacteria Meeting VI
Novel Reporter Phages to Detect Complex TB Drug Resistance and Persistence
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