2009 Bones and Teeth Gordon Research Conference and Graduate Research Seminar

描述（由申请人提供）：骨骼与牙齿戈登研究会议将于2009年7月12日至17日举行，在此之前，骨骼与牙齿研究生研究研讨会将于2009年7月11日至12日在缅因州比德福德的新英格兰大学举行。B&TGRC和GRS的目标是提供一个论坛，展示和讨论前沿的基础、转化和临床研究，以获得路径生理机制的见解，这对于开发恢复正常组织结构和功能的新治疗方法是必要的。骨骼的遗传性疾病（这里定义为骨、软骨、牙齿和相关软组织）目前在大多数情况下是无法治疗的，虽然相对罕见，但它们给医生在临床管理这些经常变形和使人衰弱的疾病患者时带来了主要困难。此外，由于预期寿命的延长，获得性骨骼疾病的发病率正在迅速增加。2009年B&T GRC的总体主题是“干细胞和骨建模和再生的调节”，该计划将包括软骨生物学和疾病，骨骼发育和重塑，牙齿发育和疾病，遗传学和骨病，成骨细胞和造血干细胞，骨免疫学：骨细胞，淋巴细胞和炎症，骨修复和再生，以及骨疾病的治疗性合成代谢靶点，所有这些都是与健康和疾病中骨骼稳态相关的新兴领域。会议将以会议主席对主题的简要概述开始，邀请演讲者进行演讲，然后进行讨论。会议还将在下午晚些时候举行海报会议，并在每次会议结束时从提交的摘要中选出一系列简短的演讲。戈登研究会议的形式和氛围将促进思想的自由交流，并讨论骨骼组织研究和治疗的未来方向。

DESCRIPTION (provided by applicant): The Bones and Teeth Gordon Research Conference will be held from July 12-17, 2009, which will be preceded by the Bones & Teeth Graduate Research Seminar from July 11- 12, 2009, at the University of New England in Biddeford, Maine. The goals of the B&TGRC & GRS is to provide a forum for presentation and discussion of cutting-edge basic, translational and clinical research in order to gain insights into path physiological mechanisms, which are necessary for the development of new therapeutic approaches for restoration of normal tissue structure and function. Genetic disorders of the skeleton (defined here as bone, cartilage, teeth and associated soft tissues) are currently untreatable for the most part, and while relatively rare, they present major difficulties to physicians in the clinical management of patients with these often deforming and debilitating diseases. Furthermore, the incidence of acquired skeletal disorders is increasing at a rapid rate due to an increase in life expectancy. The overall theme of the 2009 B&T GRC is 'Stem cells and regulation of bone modeling and regeneration' and the Program will include sessions on Cartilage Biology and disease, Skeletal development and remodeling, Dental development and disease, Genetics and bone diseases, Osteoblastic and hematopoietic stem cells, Osteoimmunology: bone cells, lymphocytes, and inflammation, Bone repair and regeneration, and Therapeutic anabolic targets in bone diseases, all of which are emerging areas of relevance to skeletal homeostasis in health and disease. Sessions will start with a brief overview of the topic by the session chairs, and presentations by invited speakers will be followed by discussion. The conference will also feature poster sessions in the late afternoons, and a series of short talks selected from submitted abstracts will be presented at the end of each session. The format and atmosphere that characterizes the Gordon Research Conferences will foster the free exchange of ideas and discussion of future directions in the study and treatment of skeletal tissues.